{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Arterial+Disease+of+Legs",
    "query": {
      "condition": "Arterial Disease of Legs"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 64,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Arterial+Disease+of+Legs&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T08:12:54.686Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00060892",
      "title": "Study of HGF Via Plasmid Vector to Improve Perfusion in Critical Limb Ischemia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Arterial Occlusive Disease",
        "Peripheral Vascular Disease",
        "Ischemia"
      ],
      "interventions": [
        {
          "name": "HGF plasmid",
          "type": "GENETIC"
        }
      ],
      "intervention_types": [
        "GENETIC"
      ],
      "sponsor": "AnGes USA, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 104,
      "start_date": "2003-04",
      "completion_date": "2007-01",
      "has_results": false,
      "last_update_posted_date": "2008-01-11",
      "last_synced_at": "2026-06-26T08:12:54.686Z",
      "location_count": 24,
      "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 19 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00060892"
    },
    {
      "nct_id": "NCT00311805",
      "title": "Autologous CD34+ Stem Cell Injection for Severe Intermittent Claudication (Leg Pain)",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Peripheral Artery Disease",
        "Severe Intermittent Claudication"
      ],
      "interventions": [
        {
          "name": "Autologous Stem Cells (CD34+)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Losordo, Douglas, M.D.",
      "sponsor_class": "INDIV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2006-04",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2015-03-31",
      "last_synced_at": "2026-06-26T08:12:54.686Z",
      "location_count": 2,
      "location_summary": "Birmingham, Alabama • Chicago, Illinois",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00311805"
    },
    {
      "nct_id": "NCT04337723",
      "title": "Implementation of ABI and WIfI in Rural Health Clinics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Peripheral Arterial Disease",
        "Diabetic Foot",
        "Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "ABI/WIFI scoring",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 135,
      "start_date": "2020-03-10",
      "completion_date": "2022-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-04-26",
      "last_synced_at": "2026-06-26T08:12:54.686Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04337723"
    },
    {
      "nct_id": "NCT03462472",
      "title": "Effect of Lower Leg Heating and Transcutaneous Electrical Nerve Stimulation on Exercise Capacity in Patients With PAD",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Peripheral Arterial Disease"
      ],
      "interventions": [
        {
          "name": "Lower leg heating",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Lower leg transcutaneous electrical nerve stimulation (TENS)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Salisbury University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "40 Years to 85 Years"
      },
      "enrollment_count": 10,
      "start_date": "2015-11-15",
      "completion_date": "2018-06",
      "has_results": false,
      "last_update_posted_date": "2018-03-12",
      "last_synced_at": "2026-06-26T08:12:54.686Z",
      "location_count": 1,
      "location_summary": "Salisbury, Maryland",
      "locations": [
        {
          "city": "Salisbury",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03462472"
    },
    {
      "nct_id": "NCT05007301",
      "title": "Geko™ Cross Therapy Registry - Wound",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Wound",
        "Venous Leg Ulcer",
        "Diabetic Foot Ulcer",
        "Arterial Leg Ulcer"
      ],
      "interventions": [
        {
          "name": "geko device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Firstkind Ltd",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2500,
      "start_date": "2022-04-04",
      "completion_date": "2028-03",
      "has_results": false,
      "last_update_posted_date": "2024-03-01",
      "last_synced_at": "2026-06-26T08:12:54.686Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05007301"
    },
    {
      "nct_id": "NCT00913900",
      "title": "Safety Study of Adult Stem Cells to Treat Patients With Severe Leg Artery Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Critical Limb Ischemia",
        "Arterial Occlusive Disease",
        "Vascular Diseases"
      ],
      "interventions": [
        {
          "name": "autologous CD133+ cells",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "21 Years to 90 Years"
      },
      "enrollment_count": 10,
      "start_date": "2009-05",
      "completion_date": "2013-12",
      "has_results": false,
      "last_update_posted_date": "2014-12-05",
      "last_synced_at": "2026-06-26T08:12:54.686Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00913900"
    },
    {
      "nct_id": "NCT03194776",
      "title": "Study of LLG783 in Patients With Peripheral Artery Disease (PAD) and Intermittent Claudication",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Peripheral Artery Disease (PAD); Intermittent Claudication"
      ],
      "interventions": [
        {
          "name": "LLG783",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "40 Years to 85 Years"
      },
      "enrollment_count": 46,
      "start_date": "2017-09-20",
      "completion_date": "2018-12-27",
      "has_results": true,
      "last_update_posted_date": "2021-01-05",
      "last_synced_at": "2026-06-26T08:12:54.686Z",
      "location_count": 2,
      "location_summary": "Jacksonville, Florida • Columbus, Ohio",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03194776"
    },
    {
      "nct_id": "NCT01378260",
      "title": "Comparative Effectiveness Research Study of Peripheral Arterial Disease (PAD)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Peripheral Arterial Disease",
        "Claudication"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 323,
      "start_date": "2011-07",
      "completion_date": "2015-08",
      "has_results": false,
      "last_update_posted_date": "2017-05-18",
      "last_synced_at": "2026-06-26T08:12:54.686Z",
      "location_count": 12,
      "location_summary": "Bellevue, Washington • Bellingham, Washington • Everett, Washington + 6 more",
      "locations": [
        {
          "city": "Bellevue",
          "state": "Washington"
        },
        {
          "city": "Bellingham",
          "state": "Washington"
        },
        {
          "city": "Everett",
          "state": "Washington"
        },
        {
          "city": "Federal Way",
          "state": "Washington"
        },
        {
          "city": "Puyallup",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01378260"
    },
    {
      "nct_id": "NCT01731990",
      "title": "Safety, Tolerability and Efficacy of ACZ885 on Leg Artery Structure in Patients With Peripheral Artery Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Peripheral Artery Disease"
      ],
      "interventions": [
        {
          "name": "Canakinumab (ACZ885)",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 38,
      "start_date": "2012-10-30",
      "completion_date": "2016-08-04",
      "has_results": true,
      "last_update_posted_date": "2025-04-29",
      "last_synced_at": "2026-06-26T08:12:54.686Z",
      "location_count": 8,
      "location_summary": "Phoenix, Arizona • Jacksonville, Florida • Chicago, Illinois + 4 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Lutherville",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01731990"
    },
    {
      "nct_id": "NCT00060996",
      "title": "Study of Remodulin in Patients With Critical Limb Ischemia With No Planned Revascularization Procedures",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Critical Limb Ischemia",
        "Peripheral Vascular Disease",
        "Foot Ulcers",
        "Rest Leg Pain"
      ],
      "interventions": [
        {
          "name": "Remodulin® (treprostinil sodium) Injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "United Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 30,
      "start_date": "2003-02",
      "completion_date": "2004-09",
      "has_results": false,
      "last_update_posted_date": "2013-03-07",
      "last_synced_at": "2026-06-26T08:12:54.686Z",
      "location_count": 7,
      "location_summary": "Tampa, Florida • Worcester, Massachusetts • Minneapolis, Minnesota + 4 more",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Worcester",
          "state": "Massachusetts"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00060996"
    }
  ]
}