{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Arterial+Dysfunction",
    "query": {
      "condition": "Arterial Dysfunction"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 190,
    "total_pages": 19,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Arterial+Dysfunction&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T13:40:00.219Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03184155",
      "title": "Prevention of Coronary Microvascular Dysfunction Post-PCI by Intracoronary Nicardipine",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "Nicardipine",
          "type": "DRUG"
        },
        {
          "name": "Sterile Saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2025-12",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2024-04-26",
      "last_synced_at": "2026-06-10T13:40:00.219Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03184155"
    },
    {
      "nct_id": "NCT04136288",
      "title": "Low Intensity Shock Wave Therapy in the Management of Erectile Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Erectile Dysfunction"
      ],
      "interventions": [
        {
          "name": "MoreNova",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "55 Years",
        "sex": "MALE",
        "summary": "40 Years to 55 Years · Male only"
      },
      "enrollment_count": 6,
      "start_date": "2019-12-01",
      "completion_date": "2023-07-01",
      "has_results": true,
      "last_update_posted_date": "2024-11-12",
      "last_synced_at": "2026-06-10T13:40:00.219Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04136288"
    },
    {
      "nct_id": "NCT01465360",
      "title": "Performance of AclarusDx™, a Blood-Based Transcriptomic Test for AD, in US Patients Newly Referred to a Memory Center",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer's Disease",
        "Mild Cognitive Impairment",
        "Vascular Dementia",
        "Fronto-temporal Dementia",
        "Primary Progressive Aphasia",
        "Parkinson' Disease Dementia",
        "Mixed Dementia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Exonhit",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 160,
      "start_date": "2011-11",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2012-07-06",
      "last_synced_at": "2026-06-10T13:40:00.219Z",
      "location_count": 3,
      "location_summary": "Las Vegas, Nevada • Cleveland, Ohio • Lakewood, Ohio",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Lakewood",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01465360"
    },
    {
      "nct_id": "NCT03334201",
      "title": "Age-associated Arterial Dysfunction, Western Diet, and Aerobic Exercise: Role of the Gut Microbiome",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging"
      ],
      "interventions": [
        {
          "name": "Western Diet",
          "type": "OTHER"
        },
        {
          "name": "Non-Western Diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Colorado, Boulder",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 120,
      "start_date": "2018-03-15",
      "completion_date": "2021-12-31",
      "has_results": false,
      "last_update_posted_date": "2021-10-28",
      "last_synced_at": "2026-06-10T13:40:00.219Z",
      "location_count": 1,
      "location_summary": "Boulder, Colorado",
      "locations": [
        {
          "city": "Boulder",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03334201"
    },
    {
      "nct_id": "NCT04224181",
      "title": "Inflammation and Cardiovascular Health in Women",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "HIV/AIDS",
        "Myocardial Infarction"
      ],
      "interventions": [
        {
          "name": "Cardiac PET",
          "type": "RADIATION"
        },
        {
          "name": "99mTc-tilmanocept SPECT/CT",
          "type": "RADIATION"
        },
        {
          "name": "Contrast Enhanced Coronary and Aortic Computed Tomography Angiography",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "RADIATION"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "79 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 79 Years · Female only"
      },
      "enrollment_count": 62,
      "start_date": "2020-02-03",
      "completion_date": "2023-11-09",
      "has_results": false,
      "last_update_posted_date": "2024-02-20",
      "last_synced_at": "2026-06-10T13:40:00.219Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04224181"
    },
    {
      "nct_id": "NCT00005671",
      "title": "Quality of Life in Patients With Chronic Ischemic Heart Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ischemic Heart Disease",
        "Myocardial Ischemia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institutes of Health Clinical Center (CC)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 105,
      "start_date": "2000-05",
      "completion_date": "2002-05",
      "has_results": false,
      "last_update_posted_date": "2008-03-04",
      "last_synced_at": "2026-06-10T13:40:00.219Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00005671"
    },
    {
      "nct_id": "NCT05634031",
      "title": "Imaging Coronary Microvascular Dysfunction (CMD) Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Angina",
        "Non-obstructive Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "PET imaging",
          "type": "RADIATION"
        },
        {
          "name": "Coronary CT angiogram",
          "type": "RADIATION"
        },
        {
          "name": "Functional Angiography",
          "type": "PROCEDURE"
        },
        {
          "name": "Treadmill exercise stress study",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "RADIATION",
        "PROCEDURE"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2023-04-26",
      "completion_date": "2027-03-01",
      "has_results": false,
      "last_update_posted_date": "2025-04-16",
      "last_synced_at": "2026-06-10T13:40:00.219Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05634031"
    },
    {
      "nct_id": "NCT00098072",
      "title": "Endothelial Cell Dysfunction in Pulmonary Hypertension",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Secondary Pulmonary Arterial Hypertension"
      ],
      "interventions": [
        {
          "name": "Heart Catheterization",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "National Institutes of Health Clinical Center (CC)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 27,
      "start_date": "2000-05-17",
      "completion_date": "2009-07-08",
      "has_results": false,
      "last_update_posted_date": "2026-05-22",
      "last_synced_at": "2026-06-10T13:40:00.219Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00098072"
    },
    {
      "nct_id": "NCT05741060",
      "title": "Effect of Equol Supplementation on Arterial Stiffness and Cognition in Healthy Volunteers",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Arterial Stiffness",
        "White Matter Lesions",
        "Cognitive Decline"
      ],
      "interventions": [
        {
          "name": "S-equol",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Akira Sekikawa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "65 Years to 85 Years"
      },
      "enrollment_count": 369,
      "start_date": "2023-06-29",
      "completion_date": "2027-01-30",
      "has_results": false,
      "last_update_posted_date": "2025-09-29",
      "last_synced_at": "2026-06-10T13:40:00.219Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia • Winston-Salem, North Carolina • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05741060"
    },
    {
      "nct_id": "NCT05860127",
      "title": "Cognitive Stimulation Therapy for Dementia: A Two-Armed Pragmatic Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dementia",
        "Cognitive Impairment, Mild",
        "Dementia, Vascular",
        "Dementia, Mixed",
        "Dementia With Lewy Bodies",
        "Dementia Frontal",
        "Dementia Moderate",
        "Dementia of Alzheimer Type",
        "Dementia, Mild"
      ],
      "interventions": [
        {
          "name": "Referral for Cognitive Stimulation Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "No change to Standard of Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Massachusetts, Amherst",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 133,
      "start_date": "2023-04-10",
      "completion_date": "2025-06-12",
      "has_results": true,
      "last_update_posted_date": "2026-03-23",
      "last_synced_at": "2026-06-10T13:40:00.219Z",
      "location_count": 2,
      "location_summary": "Farmington, Connecticut • New Haven, Connecticut",
      "locations": [
        {
          "city": "Farmington",
          "state": "Connecticut"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05860127"
    }
  ]
}