{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Arthritis+of+Ankle",
    "query": {
      "condition": "Arthritis of Ankle"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 42,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Arthritis+of+Ankle&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T01:03:59.836Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03674905",
      "title": "Peripheral Nerve Block Compared to Intra-articular Injection for TAA Post-operative Pain",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Arthritis",
        "Ankle Arthropathy"
      ],
      "interventions": [
        {
          "name": "Intra-articular injection",
          "type": "PROCEDURE"
        },
        {
          "name": "Peripheral nerve block",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Slocum Research & Education Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 50,
      "start_date": "2016-11-29",
      "completion_date": "2020-12",
      "has_results": false,
      "last_update_posted_date": "2018-09-18",
      "last_synced_at": "2026-07-23T01:03:59.836Z",
      "location_count": 1,
      "location_summary": "Eugene, Oregon",
      "locations": [
        {
          "city": "Eugene",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03674905"
    },
    {
      "nct_id": "NCT04238143",
      "title": "Adipose-Derived Biocellular Regenerative Therapy for Osteoarthritis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis",
        "Osteo Arthritis Knee",
        "Osteo Arthritis Shoulders",
        "Osteoarthritis of Multiple Joints",
        "Osteoarthritis, Hip",
        "Osteoarthritis - Ankle/Foot"
      ],
      "interventions": [
        {
          "name": "Tissue Stromal Vascular Fraction (tSVF) Arm 1",
          "type": "PROCEDURE"
        },
        {
          "name": "PRP Concentrate Arm 1",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Tissue Stromal Vascular Fraction (tSVF) Arm 2",
          "type": "PROCEDURE"
        },
        {
          "name": "PRP Concentrate Arm 2",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Cellular Stromal Vascular Fraction (cSVF) Arm 2",
          "type": "PROCEDURE"
        },
        {
          "name": "Cellular Stromal Vascular Fraction (cSVF) Arm 3",
          "type": "PROCEDURE"
        },
        {
          "name": "Sterile Normal Saline (IV Solution)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "Healeon Medical Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 100,
      "start_date": "2020-01-10",
      "completion_date": "2027-09-30",
      "has_results": false,
      "last_update_posted_date": "2024-10-01",
      "last_synced_at": "2026-07-23T01:03:59.836Z",
      "location_count": 2,
      "location_summary": "Valencia, California • Stevensville, Montana",
      "locations": [
        {
          "city": "Valencia",
          "state": "California"
        },
        {
          "city": "Stevensville",
          "state": "Montana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04238143"
    },
    {
      "nct_id": "NCT01117909",
      "title": "Effects of Talocrural Joint Mobilizations in the Treatment of Subacute Lateral Ankle Sprains",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Sprain"
      ],
      "interventions": [
        {
          "name": "Mobilization therapy in addition to standard therapy",
          "type": "OTHER"
        },
        {
          "name": "Sham intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 60,
      "start_date": "2010-04",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2011-05-30",
      "last_synced_at": "2026-07-23T01:03:59.836Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01117909"
    },
    {
      "nct_id": "NCT02038140",
      "title": "Zimmer Trabecular Metal Total Ankle PMCF",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Arthritis",
        "Rheumatoid Arthritis",
        "Post Traumatic Arthritis"
      ],
      "interventions": [
        {
          "name": "Zimmer Trabecular Metal Total Ankle System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2014-03",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-07-09",
      "last_synced_at": "2026-07-23T01:03:59.836Z",
      "location_count": 5,
      "location_summary": "Sacramento, California • Grand Rapids, Michigan • Charlotte, North Carolina + 2 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Grand Rapids",
          "state": "Michigan"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02038140"
    },
    {
      "nct_id": "NCT04118894",
      "title": "Wright Foot & Ankle Post-Market Observational Study",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Arthritis",
        "Rheumatoid Arthritis",
        "Fracture",
        "Trauma Injury",
        "Fusion of Joint"
      ],
      "interventions": [
        {
          "name": "Foot and Ankle Devices",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stryker Trauma and Extremities",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 119,
      "start_date": "2020-01-22",
      "completion_date": "2023-07-12",
      "has_results": true,
      "last_update_posted_date": "2025-01-14",
      "last_synced_at": "2026-07-23T01:03:59.836Z",
      "location_count": 2,
      "location_summary": "Hamilton, New Jersey • Charlotte, North Carolina",
      "locations": [
        {
          "city": "Hamilton",
          "state": "New Jersey"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04118894"
    },
    {
      "nct_id": "NCT02629731",
      "title": "Orthotic Dose Response Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Osteoarthritis",
        "Flat Foot or Pes Planus"
      ],
      "interventions": [
        {
          "name": "custom orthoses with varying degrees of hindfoot posting",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 35,
      "start_date": "2016-07-01",
      "completion_date": "2023-12-29",
      "has_results": false,
      "last_update_posted_date": "2024-06-21",
      "last_synced_at": "2026-07-23T01:03:59.836Z",
      "location_count": 2,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02629731"
    },
    {
      "nct_id": "NCT02664337",
      "title": "Conjoint Analysis of Patient Preferences in Joint Interventions",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthritis",
        "Femoroacetabular Impingement",
        "Osteochondritis Dissecans",
        "Hip Fractures",
        "Ankle Fractures",
        "Tibial Fractures"
      ],
      "interventions": [
        {
          "name": "Decision tool",
          "type": "OTHER"
        },
        {
          "name": "Standard treatment information",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 2310,
      "start_date": "2016-02",
      "completion_date": "2027-07",
      "has_results": false,
      "last_update_posted_date": "2026-02-04",
      "last_synced_at": "2026-07-23T01:03:59.836Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02664337"
    },
    {
      "nct_id": "NCT07118501",
      "title": "A Prospective, Post-Market, Clinical Follow-up Study of the Incompass™ Total Ankle System",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Post Traumatic Arthritis",
        "Osteoarthritis",
        "Total Ankle Replacement",
        "Total Ankle Prosthesis"
      ],
      "interventions": [
        {
          "name": "Total Ankle Replacement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stryker Trauma and Extremities",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2026-02-06",
      "completion_date": "2038-09-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-24",
      "last_synced_at": "2026-07-23T01:03:59.836Z",
      "location_count": 4,
      "location_summary": "Morton Grove, Illinois • Louisville, Kentucky • Eugene, Oregon + 1 more",
      "locations": [
        {
          "city": "Morton Grove",
          "state": "Illinois"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Eugene",
          "state": "Oregon"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07118501"
    },
    {
      "nct_id": "NCT06384651",
      "title": "Intraosseous vs. Intravenous Vancomycin Administration in Total Ankle Arthroplasty",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Infections",
        "Ankle Arthritis"
      ],
      "interventions": [
        {
          "name": "Intraosseous Vancomycin Injection",
          "type": "DRUG"
        },
        {
          "name": "Intravenous Vancomycin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The Methodist Hospital Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2024-12-03",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2025-01-24",
      "last_synced_at": "2026-07-23T01:03:59.836Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06384651"
    },
    {
      "nct_id": "NCT00391365",
      "title": "Treatment Outcomes for Ankle Arthritis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Gait analysis",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 368,
      "start_date": "2005-03-01",
      "completion_date": "2025-12-31",
      "has_results": true,
      "last_update_posted_date": "2026-01-26",
      "last_synced_at": "2026-07-23T01:03:59.836Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00391365"
    }
  ]
}