{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Arthritis+of+Ankle&page=2",
    "query": {
      "condition": "Arthritis of Ankle",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Arthritis+of+Ankle&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T06:24:11.068Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01117909",
      "title": "Effects of Talocrural Joint Mobilizations in the Treatment of Subacute Lateral Ankle Sprains",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Sprain"
      ],
      "interventions": [
        {
          "name": "Mobilization therapy in addition to standard therapy",
          "type": "OTHER"
        },
        {
          "name": "Sham intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 60,
      "start_date": "2010-04",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2011-05-30",
      "last_synced_at": "2026-07-24T06:24:11.068Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01117909"
    },
    {
      "nct_id": "NCT05456295",
      "title": "Comparative Effect of Carbon Fiber Orthosis Cuff Design on Preference, Comfort, and Mechanics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy",
        "Lower Limb Injury",
        "Post-Traumatic Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Carbon Fiber Custom Dynamic Orthosis (CDO)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 35,
      "start_date": "2023-05-17",
      "completion_date": "2025-09-29",
      "has_results": false,
      "last_update_posted_date": "2026-01-15",
      "last_synced_at": "2026-07-24T06:24:11.068Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05456295"
    },
    {
      "nct_id": "NCT04562896",
      "title": "Iterative Design of Custom Dynamic Orthoses to Reduce Articular Contact Stress",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ankle Fractures",
        "Post-traumatic Osteoarthritis",
        "Osteoarthritis Ankle"
      ],
      "interventions": [
        {
          "name": "Custom Carbon Fiber Dynamic Orthosis (CDO)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 22,
      "start_date": "2020-01-08",
      "completion_date": "2023-10-05",
      "has_results": true,
      "last_update_posted_date": "2026-01-30",
      "last_synced_at": "2026-07-24T06:24:11.068Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04562896"
    },
    {
      "nct_id": "NCT02879149",
      "title": "Long-term Safety and Effectiveness of AUGMENT® Bone Graft Compared to Autologous Bone Graft",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ankle and Hindfoot Arthrodesis"
      ],
      "interventions": [
        {
          "name": "AUGMENT® Bone Graft",
          "type": "DEVICE"
        },
        {
          "name": "Standard of Care",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "BioMimetic Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2016-08",
      "completion_date": "2018-12",
      "has_results": false,
      "last_update_posted_date": "2018-03-27",
      "last_synced_at": "2026-07-24T06:24:11.068Z",
      "location_count": 21,
      "location_summary": "Tucson, Arizona • Capitola, California • San Francisco, California + 18 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Capitola",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Royal Palm Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02879149"
    },
    {
      "nct_id": "NCT01243814",
      "title": "A Double-blind RCT of a Single Dose of Hyaluronan in the Treatment of Osteoarthritis of the Ankle",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "hyaluronate intra-articular injection",
          "type": "DEVICE"
        },
        {
          "name": "placebo injection",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Henry DeGroot, M.D.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 69,
      "start_date": "2009-10",
      "completion_date": "2010-09",
      "has_results": false,
      "last_update_posted_date": "2012-03-20",
      "last_synced_at": "2026-07-24T06:24:11.068Z",
      "location_count": 1,
      "location_summary": "Newton, Massachusetts",
      "locations": [
        {
          "city": "Newton",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01243814"
    },
    {
      "nct_id": "NCT03686241",
      "title": "The Use of a Dynamic Compression Intramedullary Nail for Tibiotalocalcaneal Arthrodesis",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ankle Arthritis",
        "Foot Arthritis"
      ],
      "interventions": [
        {
          "name": "Tibiotalocalcaneal (TTC) arthrodesis",
          "type": "PROCEDURE"
        },
        {
          "name": "DynaNail",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "MedShape, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2017-05-22",
      "completion_date": "2022-05",
      "has_results": false,
      "last_update_posted_date": "2021-03-05",
      "last_synced_at": "2026-07-24T06:24:11.068Z",
      "location_count": 1,
      "location_summary": "Boise, Idaho",
      "locations": [
        {
          "city": "Boise",
          "state": "Idaho"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03686241"
    },
    {
      "nct_id": "NCT02664337",
      "title": "Conjoint Analysis of Patient Preferences in Joint Interventions",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthritis",
        "Femoroacetabular Impingement",
        "Osteochondritis Dissecans",
        "Hip Fractures",
        "Ankle Fractures",
        "Tibial Fractures"
      ],
      "interventions": [
        {
          "name": "Decision tool",
          "type": "OTHER"
        },
        {
          "name": "Standard treatment information",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 2310,
      "start_date": "2016-02",
      "completion_date": "2027-07",
      "has_results": false,
      "last_update_posted_date": "2026-02-04",
      "last_synced_at": "2026-07-24T06:24:11.068Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02664337"
    },
    {
      "nct_id": "NCT03780452",
      "title": "Compression Nail for Tibiocalcaneal Arthrodesis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Subtalar Arthritis",
        "Ankle Arthritis"
      ],
      "interventions": [
        {
          "name": "novel dynamic compression intramedullary nail",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "110 Years",
        "sex": "ALL",
        "summary": "18 Years to 110 Years"
      },
      "enrollment_count": 13,
      "start_date": "2020-11-15",
      "completion_date": "2024-07-10",
      "has_results": true,
      "last_update_posted_date": "2025-05-31",
      "last_synced_at": "2026-07-24T06:24:11.068Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03780452"
    },
    {
      "nct_id": "NCT07231471",
      "title": "Platelet Rich Plasma for Musculoskeletal Conditions",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis (OA)",
        "Osteoarthritis (OA) of the Knee",
        "Osteoarthritis (OA) of the Hip",
        "Osteoarthritis (OA) of the Shoulder",
        "Osteoarthritis Ankle",
        "Elbow Osteoarthritis",
        "Epicondylitis of the Elbow",
        "Plantar Fasciitis of Both Feet",
        "Tendinopathy"
      ],
      "interventions": [
        {
          "name": "Platelet Rich Plasma Injection",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Platelet Rich Plasma Preparation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DEVICE"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10000,
      "start_date": "2025-12-29",
      "completion_date": "2035-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-06",
      "last_synced_at": "2026-07-24T06:24:11.068Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07231471"
    },
    {
      "nct_id": "NCT00642382",
      "title": "Safety and Effectiveness of Agilus (Hyaluronic Acid) for Ankle Osteoarthritis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "OSTEOARTHRITIS"
      ],
      "interventions": [
        {
          "name": "Agilus",
          "type": "DEVICE"
        },
        {
          "name": "Normal saline",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cartiva, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "18 Years to 95 Years"
      },
      "enrollment_count": 17,
      "start_date": "2008-04",
      "completion_date": "2008-12",
      "has_results": true,
      "last_update_posted_date": "2017-08-17",
      "last_synced_at": "2026-07-24T06:24:11.068Z",
      "location_count": 19,
      "location_summary": "Farmington, Connecticut • Royal Palm Beach, Florida • Chicago, Illinois + 14 more",
      "locations": [
        {
          "city": "Farmington",
          "state": "Connecticut"
        },
        {
          "city": "Royal Palm Beach",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00642382"
    }
  ]
}