{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Arthropathy+of+Knee+Joint&page=2",
    "query": {
      "condition": "Arthropathy of Knee Joint",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Arthropathy+of+Knee+Joint&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T14:15:38.318Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01415856",
      "title": "Use of Pulsed Electromagnetic Fields for Postoperative Knee Pain",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Active Device (Torino II)",
          "type": "DEVICE"
        },
        {
          "name": "Sham Device (Torino II)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Center for Joint Surgery and Sports Medicine, Maryland",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2010-10",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2011-08-12",
      "last_synced_at": "2026-06-26T14:15:38.318Z",
      "location_count": 1,
      "location_summary": "Hagerstown, Maryland",
      "locations": [
        {
          "city": "Hagerstown",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01415856"
    },
    {
      "nct_id": "NCT03326999",
      "title": "Does Adding an Additional Numbing Medication Injection in the Thigh Help With Pain Control After Knee Replacement Surgery?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Knee Osteoarthritis",
        "Knee Rheumatism"
      ],
      "interventions": [
        {
          "name": "Obturator nerve regional block",
          "type": "DRUG"
        },
        {
          "name": "Adductor canal regional block",
          "type": "DRUG"
        },
        {
          "name": "Saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 60,
      "start_date": "2017-12-11",
      "completion_date": "2018-12-18",
      "has_results": true,
      "last_update_posted_date": "2020-09-30",
      "last_synced_at": "2026-06-26T14:15:38.318Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03326999"
    },
    {
      "nct_id": "NCT05197036",
      "title": "A Global Clinical Study Investigating the Safety and Effectiveness of Smith and Nephew's Porous Knee System in Patients Who Need a Total Knee Replacement Due to Degenerative Arthritis, Post-traumatic Arthritis or Inflammatory Arthritis",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteoarthritis",
        "Post-traumatic Arthritis",
        "Rheumatoid Arthritis"
      ],
      "interventions": [
        {
          "name": "Total Knee Arthroplasty",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Smith & Nephew, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 299,
      "start_date": "2021-12-21",
      "completion_date": "2033-12-25",
      "has_results": false,
      "last_update_posted_date": "2026-06-25",
      "last_synced_at": "2026-06-26T14:15:38.318Z",
      "location_count": 12,
      "location_summary": "Atlanta, Georgia • Boston, Massachusetts • Novi, Michigan + 8 more",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Novi",
          "state": "Michigan"
        },
        {
          "city": "East Syracuse",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05197036"
    },
    {
      "nct_id": "NCT02034032",
      "title": "Regenexx™ SD Versus Exercise Therapy for Treatment of Knee Osteoarthritis With Historical Comparison to TKA",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Regenexx SD",
          "type": "PROCEDURE"
        },
        {
          "name": "Exercise Therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BEHAVIORAL"
      ],
      "sponsor": "Regenexx, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 48,
      "start_date": "2014-01",
      "completion_date": "2018-12",
      "has_results": false,
      "last_update_posted_date": "2019-01-04",
      "last_synced_at": "2026-06-26T14:15:38.318Z",
      "location_count": 1,
      "location_summary": "Des Plaines, Illinois",
      "locations": [
        {
          "city": "Des Plaines",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02034032"
    },
    {
      "nct_id": "NCT06715709",
      "title": "How Many Dexamethasone Doses Should Be Given Perioperatively?",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Arthropathy of Knee"
      ],
      "interventions": [
        {
          "name": "Dexamethasone IV",
          "type": "DRUG"
        },
        {
          "name": "Dexamethasone IV+Oral",
          "type": "DRUG"
        },
        {
          "name": "Dexamethasone IV+Oral 2 Day",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 339,
      "start_date": "2025-03-25",
      "completion_date": "2027-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-06",
      "last_synced_at": "2026-06-26T14:15:38.318Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06715709"
    },
    {
      "nct_id": "NCT03130335",
      "title": "Intra-articular Autologous Bone Marrow Aspirate Injection for Knee Osteoarthritis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis, Knee"
      ],
      "interventions": [
        {
          "name": "BMA Injection",
          "type": "PROCEDURE"
        },
        {
          "name": "BMA",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BIOLOGICAL"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 13,
      "start_date": "2017-04-28",
      "completion_date": "2019-10-01",
      "has_results": false,
      "last_update_posted_date": "2020-01-14",
      "last_synced_at": "2026-06-26T14:15:38.318Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03130335"
    },
    {
      "nct_id": "NCT04636190",
      "title": "Triathlon All-Polyethylene Tibia Outcomes Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthropathy of Knee",
        "Replacement",
        "Knee Arthritis"
      ],
      "interventions": [
        {
          "name": "Triathlon All-Polyethylene Tibia Knee",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stryker Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 204,
      "start_date": "2021-07-02",
      "completion_date": "2033-10",
      "has_results": false,
      "last_update_posted_date": "2026-02-27",
      "last_synced_at": "2026-06-26T14:15:38.318Z",
      "location_count": 6,
      "location_summary": "Lansing, Michigan • Buffalo, New York • Syracuse, New York + 3 more",
      "locations": [
        {
          "city": "Lansing",
          "state": "Michigan"
        },
        {
          "city": "Buffalo",
          "state": "New York"
        },
        {
          "city": "Syracuse",
          "state": "New York"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04636190"
    },
    {
      "nct_id": "NCT00108810",
      "title": "Transdermal Ketoprofen to Treat Mild to Moderate Osteoarthritis (OA) Pain of the Knee",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pain",
        "Osteoarthritis, Knee"
      ],
      "interventions": [
        {
          "name": "Transdermal Ketoprofen Patch with CHADD",
          "type": "DRUG"
        },
        {
          "name": "Placebo transdermal patch",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "ZARS Pharma Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "40 Years to 75 Years"
      },
      "enrollment_count": 118,
      "start_date": "2005-04",
      "completion_date": "2005-10",
      "has_results": false,
      "last_update_posted_date": "2012-06-05",
      "last_synced_at": "2026-06-26T14:15:38.318Z",
      "location_count": 5,
      "location_summary": "Buena Park, California • Washington D.C., District of Columbia • Daytona Beach, Florida + 2 more",
      "locations": [
        {
          "city": "Buena Park",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Daytona Beach",
          "state": "Florida"
        },
        {
          "city": "Pembroke Pines",
          "state": "Florida"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00108810"
    },
    {
      "nct_id": "NCT03661996",
      "title": "An Open-label, 8-week Safety, Efficacy, and Assessment of Cooling Methods for Administration of CNTX-4975-05 for Knee OA",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "CNTX-4975-05",
          "type": "DRUG"
        },
        {
          "name": "Lidocaine without epinephrine",
          "type": "DRUG"
        },
        {
          "name": "ElastoGel",
          "type": "DEVICE"
        },
        {
          "name": "Breg Ice Water Pump",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Centrexion Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "40 Years to 95 Years"
      },
      "enrollment_count": 854,
      "start_date": "2018-09-18",
      "completion_date": "2019-10-22",
      "has_results": true,
      "last_update_posted_date": "2022-03-09",
      "last_synced_at": "2026-06-26T14:15:38.318Z",
      "location_count": 28,
      "location_summary": "Birmingham, Alabama • Peoria, Arizona • Tucson, Arizona + 24 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Peoria",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Carmichael",
          "state": "California"
        },
        {
          "city": "Cerritos",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03661996"
    },
    {
      "nct_id": "NCT01379118",
      "title": "Comparison of Clinical Outcomes and Performance of Total Knee Replacement Patients Before and After Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Degenerative Joint Disease",
        "Osteoarthritis",
        "Knee Injury, Trauma",
        "Connective Tissue Disorder",
        "Pain",
        "Loss of Function"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 50,
      "start_date": "2012-07",
      "completion_date": "2016-04",
      "has_results": false,
      "last_update_posted_date": "2016-09-15",
      "last_synced_at": "2026-06-26T14:15:38.318Z",
      "location_count": 1,
      "location_summary": "San Bernardino, California",
      "locations": [
        {
          "city": "San Bernardino",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01379118"
    }
  ]
}