{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Arthroplasty%2C+Replacement",
    "query": {
      "condition": "Arthroplasty, Replacement"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 467,
    "total_pages": 47,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Arthroplasty%2C+Replacement&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T06:46:59.025Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07404982",
      "title": "Reversal of Spinal Anesthesia Residual Motor Block Via Intrathecal Catheter",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Joint Replacement Surgery"
      ],
      "interventions": [
        {
          "name": "Normal Saline 10 mL Injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 20,
      "start_date": "2026-03-19",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-04-20",
      "last_synced_at": "2026-05-22T06:46:59.025Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07404982"
    },
    {
      "nct_id": "NCT03152357",
      "title": "A Retrospective Study to Evaluate the ConforMIS iUni, iDuo & iTotal® KRS",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteoarthritis, Knee",
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "ConforMIS iUni, iDuo, or iTotal (CR)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Restor3D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 950,
      "start_date": "2017-04-01",
      "completion_date": "2019-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-10-25",
      "last_synced_at": "2026-05-22T06:46:59.025Z",
      "location_count": 1,
      "location_summary": "Boynton Beach, Florida",
      "locations": [
        {
          "city": "Boynton Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03152357"
    },
    {
      "nct_id": "NCT05190666",
      "title": "Healthy Living After Knee Replacement",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthroplasty",
        "Overweight and Obesity"
      ],
      "interventions": [
        {
          "name": "PACE Weight Loss program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Chronic Disease Self-Management",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 182,
      "start_date": "2022-01-04",
      "completion_date": "2027-07-30",
      "has_results": false,
      "last_update_posted_date": "2026-04-03",
      "last_synced_at": "2026-05-22T06:46:59.025Z",
      "location_count": 1,
      "location_summary": "Columbia, South Carolina",
      "locations": [
        {
          "city": "Columbia",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05190666"
    },
    {
      "nct_id": "NCT01468129",
      "title": "Cell Saver Use in Bilateral Total Hip Arthroplasty (THA)",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "One-stage Bilateral Total Hip Replacement"
      ],
      "interventions": [
        {
          "name": "Cell Saver",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Rothman Institute Orthopaedics",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": null,
      "start_date": "2011-11",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2011-11-09",
      "last_synced_at": "2026-05-22T06:46:59.025Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01468129"
    },
    {
      "nct_id": "NCT01961986",
      "title": "Rotator Cuff Sparing Total Arthroplasty",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis",
        "Inflammatory Arthritis"
      ],
      "interventions": [
        {
          "name": "TSR - traditional subscapularis release",
          "type": "PROCEDURE"
        },
        {
          "name": "TSR - rotator cuff sparing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 108,
      "start_date": "2010-07",
      "completion_date": "2027-05-04",
      "has_results": false,
      "last_update_posted_date": "2026-01-06",
      "last_synced_at": "2026-05-22T06:46:59.025Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01961986"
    },
    {
      "nct_id": "NCT00288899",
      "title": "Benefits of 'Repeat Back' Protocols Within A Computer-Based Informed Consent Program",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Surgery",
        "Cholecystectomy, Laparoscopic",
        "Prostatectomy",
        "Arthroplasty, Replacement, Hip",
        "Endarterectomy, Carotid"
      ],
      "interventions": [
        {
          "name": "Enhanced surgical iMedConsent process (with \"repeat back\")",
          "type": "OTHER"
        },
        {
          "name": "standard surgical iMedConsent process",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 575,
      "start_date": "2006-08-07",
      "completion_date": "2009-03-31",
      "has_results": false,
      "last_update_posted_date": "2017-06-06",
      "last_synced_at": "2026-05-22T06:46:59.025Z",
      "location_count": 7,
      "location_summary": "Denver, Colorado • Tampa, Florida • Decatur, Georgia + 4 more",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Decatur",
          "state": "Georgia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00288899"
    },
    {
      "nct_id": "NCT00152971",
      "title": "Dabigatran Etexilate vs Enoxaparin in Prevention of Venous Thromboembolism (VTE) Post Total Knee Replacement",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Arthroplasty, Replacement, Knee",
        "Thromboembolism"
      ],
      "interventions": [
        {
          "name": "Dabigatran Dose 1 - day 2 to completion",
          "type": "DRUG"
        },
        {
          "name": "Dabigatran Dose 1 - day 1",
          "type": "DRUG"
        },
        {
          "name": "Dabigatran Dose 2 - day 2 to completion",
          "type": "DRUG"
        },
        {
          "name": "Dabigatran Dose 2 - day 1",
          "type": "DRUG"
        },
        {
          "name": "Enoxaparin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boehringer Ingelheim",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2615,
      "start_date": "2004-11",
      "completion_date": null,
      "has_results": true,
      "last_update_posted_date": "2014-05-05",
      "last_synced_at": "2026-05-22T06:46:59.025Z",
      "location_count": 59,
      "location_summary": "Birmingham, Alabama • Northport, Alabama • Tucson, Arizona + 48 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Northport",
          "state": "Alabama"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00152971"
    },
    {
      "nct_id": "NCT00289133",
      "title": "Gamma Vacuum Foil (GVF) Versus Cross-linked Polyethylene in Total Knee Arthroplasty Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis, Knee",
        "Arthritis, Rheumatoid"
      ],
      "interventions": [
        {
          "name": "total knee arthroplasty",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DePuy Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "Up to 80 Years"
      },
      "enrollment_count": 938,
      "start_date": "2005-02-01",
      "completion_date": "2013-05-01",
      "has_results": true,
      "last_update_posted_date": "2017-04-24",
      "last_synced_at": "2026-05-22T06:46:59.025Z",
      "location_count": 9,
      "location_summary": "Mobile, Alabama • Berkley, California • Fort Collins, Colorado + 6 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Berkley",
          "state": "California"
        },
        {
          "city": "Fort Collins",
          "state": "Colorado"
        },
        {
          "city": "Fort Lauderdale",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00289133"
    },
    {
      "nct_id": "NCT00197977",
      "title": "Addressing Patients' Expectations of Total Knee Arthroplasty in a Randomized Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Osteoarthritis",
        "Arthroplasty, Replacement, Knee"
      ],
      "interventions": [
        {
          "name": "Educational program to address patients' expectations",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 146,
      "start_date": "2001-11",
      "completion_date": "2004-09",
      "has_results": false,
      "last_update_posted_date": "2011-11-23",
      "last_synced_at": "2026-05-22T06:46:59.025Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00197977"
    },
    {
      "nct_id": "NCT01917929",
      "title": "Secur-Fit Advanced Outcomes Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthroplasty, Replacement, Hip"
      ],
      "interventions": [
        {
          "name": "Secur-Fit Advanced Hip Stem",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stryker Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 326,
      "start_date": "2013-08-15",
      "completion_date": "2024-06-13",
      "has_results": true,
      "last_update_posted_date": "2025-07-23",
      "last_synced_at": "2026-05-22T06:46:59.025Z",
      "location_count": 8,
      "location_summary": "Tucson, Arizona • Aurora, Colorado • Spring Valley, Illinois + 5 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Spring Valley",
          "state": "Illinois"
        },
        {
          "city": "Lawrenceville",
          "state": "New Jersey"
        },
        {
          "city": "Albany",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01917929"
    }
  ]
}