{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Arthroplasty%2C+Replacement&page=8",
    "query": {
      "condition": "Arthroplasty, Replacement",
      "page": 8
    },
    "page_size": 10
  },
  "pagination": {
    "page": 8,
    "page_size": 10,
    "total_count": 476,
    "total_pages": 48,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Arthroplasty%2C+Replacement&page=9&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Arthroplasty%2C+Replacement&page=7&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-03T08:01:33.731Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04974463",
      "title": "Predicting Chronic Opioid Use Following Lower Extremity Joint Arthroplasty",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Joint Pain",
        "Chronic Pain",
        "Opioid Use"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2021-07-19",
      "completion_date": "2023-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-07-27",
      "last_synced_at": "2026-10-03T08:01:33.731Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04974463"
    },
    {
      "nct_id": "NCT03272178",
      "title": "Impact of Component Design and Fixation in Total Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Arthroplasties, Knee Replacement"
      ],
      "interventions": [
        {
          "name": "Depuy total knee implant",
          "type": "DEVICE"
        },
        {
          "name": "Triathlon total knee implant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 100,
      "start_date": "2017-11-20",
      "completion_date": "2021-11-15",
      "has_results": false,
      "last_update_posted_date": "2021-12-01",
      "last_synced_at": "2026-10-03T08:01:33.731Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03272178"
    },
    {
      "nct_id": "NCT02980926",
      "title": "Mepivacaine vs. Bupivacaine Spinal Anesthetic in Total Knee Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Anesthesia, Spinal",
        "Arthroplasty, Replacement, Knee",
        "Pain Management",
        "Early Ambulation",
        "Ambulatory Surgical Procedures"
      ],
      "interventions": [
        {
          "name": "Mepivacaine",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Henry Ford Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "40 Years to 90 Years"
      },
      "enrollment_count": 32,
      "start_date": "2016-12",
      "completion_date": "2017-03",
      "has_results": false,
      "last_update_posted_date": "2017-03-27",
      "last_synced_at": "2026-10-03T08:01:33.731Z",
      "location_count": 1,
      "location_summary": "West Bloomfield, Michigan",
      "locations": [
        {
          "city": "West Bloomfield",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02980926"
    },
    {
      "nct_id": "NCT06782295",
      "title": "The Use of CCK vs PS in Revision TKAs",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Aseptic Loosening of Prosthetic Joint",
        "Instability of Prosthetic Joint",
        "Reimplantation for Periprosthetic Joint Infection",
        "Femoral Revision Indicated",
        "Tibial Component Revision"
      ],
      "interventions": [
        {
          "name": "Constrained Condylar bearing",
          "type": "DEVICE"
        },
        {
          "name": "posterior stabilized bearing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 170,
      "start_date": "2025-07-01",
      "completion_date": "2038-07-01",
      "has_results": false,
      "last_update_posted_date": "2025-11-14",
      "last_synced_at": "2026-10-03T08:01:33.731Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06782295"
    },
    {
      "nct_id": "NCT00634907",
      "title": "Prospective Genotyping For Total Hip or Knee Replacement Patients Receiving Warfarin (Coumadin)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Venous Thromboembolism",
        "Bleeding"
      ],
      "interventions": [
        {
          "name": "Pharmacogenetic-based warfarin dosing",
          "type": "GENETIC"
        },
        {
          "name": "Usual care warfarin dosing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "GENETIC",
        "OTHER"
      ],
      "sponsor": "Gwen McMillin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 263,
      "start_date": "2006-09",
      "completion_date": "2008-10",
      "has_results": true,
      "last_update_posted_date": "2017-06-08",
      "last_synced_at": "2026-10-03T08:01:33.731Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00634907"
    },
    {
      "nct_id": "NCT04360239",
      "title": "Fish Oil in Total Hip Replacement Randomized Clinical Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Total Hip Arthroplasty"
      ],
      "interventions": [
        {
          "name": "Fish Oil",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Jeffrey L Stimac MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 8,
      "start_date": "2020-06-01",
      "completion_date": "2022-07-10",
      "has_results": false,
      "last_update_posted_date": "2024-10-26",
      "last_synced_at": "2026-10-03T08:01:33.731Z",
      "location_count": 1,
      "location_summary": "Louisville, Kentucky",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04360239"
    },
    {
      "nct_id": "NCT03250767",
      "title": "Clinical Evaluation of the Integra® Titan™ Modular Shoulder System Generation 2.5 for Primary Shoulder Joint Replacement",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteo Arthritis Shoulders",
        "Traumatic Arthritis",
        "Rheumatoid Arthritis"
      ],
      "interventions": [
        {
          "name": "Integra Titan Modular Shoulder System 2.5",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Smith & Nephew, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 58,
      "start_date": "2017-08-01",
      "completion_date": "2023-03-10",
      "has_results": false,
      "last_update_posted_date": "2023-11-09",
      "last_synced_at": "2026-10-03T08:01:33.731Z",
      "location_count": 7,
      "location_summary": "Birmingham, Alabama • Columbia, Maryland • Starkville, Mississippi + 3 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Columbia",
          "state": "Maryland"
        },
        {
          "city": "Starkville",
          "state": "Mississippi"
        },
        {
          "city": "Syracuse",
          "state": "New York"
        },
        {
          "city": "Lancaster",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03250767"
    },
    {
      "nct_id": "NCT01092312",
      "title": "Signature Personalised Patient Care System With the Vanguard Knee System Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthroplasty, Replacement, Knee"
      ],
      "interventions": [
        {
          "name": "Vanguard Knee System with Signature Knee Guide",
          "type": "PROCEDURE"
        },
        {
          "name": "Vanguard Knee System with conventional Instruments",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 325,
      "start_date": "2010-03",
      "completion_date": "2016-09",
      "has_results": false,
      "last_update_posted_date": "2017-09-05",
      "last_synced_at": "2026-10-03T08:01:33.731Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01092312"
    },
    {
      "nct_id": "NCT01415856",
      "title": "Use of Pulsed Electromagnetic Fields for Postoperative Knee Pain",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Active Device (Torino II)",
          "type": "DEVICE"
        },
        {
          "name": "Sham Device (Torino II)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Center for Joint Surgery and Sports Medicine, Maryland",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2010-10",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2011-08-12",
      "last_synced_at": "2026-10-03T08:01:33.731Z",
      "location_count": 1,
      "location_summary": "Hagerstown, Maryland",
      "locations": [
        {
          "city": "Hagerstown",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01415856"
    },
    {
      "nct_id": "NCT04729686",
      "title": "The Pericapsular Nerve Block in Total Hip Arthroplasty",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hip Osteoarthritis",
        "Hip Arthropathy"
      ],
      "interventions": [
        {
          "name": "Pericapsular Nerve Block",
          "type": "DRUG"
        },
        {
          "name": "Fascia Iliaca Nerve Block",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "LifeBridge Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 78,
      "start_date": "2020-12-09",
      "completion_date": "2025-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-01-22",
      "last_synced_at": "2026-10-03T08:01:33.731Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04729686"
    }
  ]
}