{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Articular+Cartilage",
    "query": {
      "condition": "Articular Cartilage"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 99,
    "total_pages": 10,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Articular+Cartilage&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T16:09:16.099Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00949494",
      "title": "Effects of Synvisc on Cartilage in Knee Osteoarthritis (OA)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Synvisc",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Endeavor Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2006-09",
      "completion_date": "2009-02",
      "has_results": false,
      "last_update_posted_date": "2019-09-10",
      "last_synced_at": "2026-07-22T16:09:16.099Z",
      "location_count": 2,
      "location_summary": "Chicago, Illinois • Evanston, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Evanston",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00949494"
    },
    {
      "nct_id": "NCT03299959",
      "title": "Agili-C™ Implant Performance Evaluation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cartilage or Osteochondral Defects in the Knee",
        "Up to Moderate Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Agili-C implant",
          "type": "DEVICE"
        },
        {
          "name": "SSOC",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Smith & Nephew, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 251,
      "start_date": "2017-09-25",
      "completion_date": "2024-11-14",
      "has_results": true,
      "last_update_posted_date": "2025-12-05",
      "last_synced_at": "2026-07-22T16:09:16.099Z",
      "location_count": 11,
      "location_summary": "San Diego, California • New Orleans, Louisiana • Salisbury, Maryland + 7 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Salisbury",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03299959"
    },
    {
      "nct_id": "NCT02659215",
      "title": "HyaloFAST Trial for Repair of Articular Cartilage in the Knee",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Defect of Articular Cartilage"
      ],
      "interventions": [
        {
          "name": "Hyalofast",
          "type": "DEVICE"
        },
        {
          "name": "Microfracture",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Anika Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 200,
      "start_date": "2015-12",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-04-15",
      "last_synced_at": "2026-07-22T16:09:16.099Z",
      "location_count": 18,
      "location_summary": "Tempe, Arizona • Los Angeles, California • San Diego, California + 14 more",
      "locations": [
        {
          "city": "Tempe",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Tarzana",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02659215"
    },
    {
      "nct_id": "NCT06451120",
      "title": "Platelet Rich Plasma Injections In Young And Old Human Subjects",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Osteoarthritis",
        "Articular Cartilage",
        "Musculoskeletal Disorders"
      ],
      "interventions": [
        {
          "name": "Platelet-Rich Plasma (PRP) Injections",
          "type": "DRUG"
        },
        {
          "name": "Centrifuge",
          "type": "DEVICE"
        },
        {
          "name": "Control saline injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 60,
      "start_date": "2024-06-01",
      "completion_date": "2027-02-16",
      "has_results": false,
      "last_update_posted_date": "2026-03-19",
      "last_synced_at": "2026-07-22T16:09:16.099Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06451120"
    },
    {
      "nct_id": "NCT01851655",
      "title": "Anterior Cruciate Ligament Reconstruction and Plyometric Exercise",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Reconstruction"
      ],
      "interventions": [
        {
          "name": "Plyometric Exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "15 Years to 30 Years"
      },
      "enrollment_count": 25,
      "start_date": "2008-07",
      "completion_date": "2010-06",
      "has_results": true,
      "last_update_posted_date": "2014-09-18",
      "last_synced_at": "2026-07-22T16:09:16.099Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01851655"
    },
    {
      "nct_id": "NCT04000659",
      "title": "Episealer® Knee System IDE Clinical Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Lesion of Articular Cartilage of Knee"
      ],
      "interventions": [
        {
          "name": "Episealer Knee System",
          "type": "DEVICE"
        },
        {
          "name": "Microfracture",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Episurf Medical Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "30 Years to 70 Years"
      },
      "enrollment_count": 13,
      "start_date": "2020-06-18",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2024-07-30",
      "last_synced_at": "2026-07-22T16:09:16.099Z",
      "location_count": 8,
      "location_summary": "Tempe, Arizona • La Mesa, California • New Orleans, Louisiana + 5 more",
      "locations": [
        {
          "city": "Tempe",
          "state": "Arizona"
        },
        {
          "city": "La Mesa",
          "state": "California"
        },
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Hackensack",
          "state": "New Jersey"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04000659"
    },
    {
      "nct_id": "NCT00158613",
      "title": "Study of the Treatment of Articular Repair (STAR)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Articular Cartilage"
      ],
      "interventions": [
        {
          "name": "Carticel (autologous cultured chondrocyte) implantation",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Vericel Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 126,
      "start_date": "2000-03",
      "completion_date": "2005-11",
      "has_results": false,
      "last_update_posted_date": "2021-05-11",
      "last_synced_at": "2026-07-22T16:09:16.099Z",
      "location_count": 25,
      "location_summary": "Los Angeles, California • San Diego, California • Santa Monica, California + 22 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Sonoma",
          "state": "California"
        },
        {
          "city": "Lone Tree",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00158613"
    },
    {
      "nct_id": "NCT06823089",
      "title": "Early Feasibility Study of Cartilage Defect Repair",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis, Hip",
        "Femoroacetabular Impingement",
        "Osteonecrosis",
        "Legg-Calvé-Perthes Disease",
        "Osteochondral Lesion",
        "Hip Dysplasia"
      ],
      "interventions": [
        {
          "name": "ReNew Hip Implant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cytex Therapeutics, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "14 Years to 64 Years"
      },
      "enrollment_count": 15,
      "start_date": "2025-11-06",
      "completion_date": "2031-10",
      "has_results": false,
      "last_update_posted_date": "2026-02-17",
      "last_synced_at": "2026-07-22T16:09:16.099Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06823089"
    },
    {
      "nct_id": "NCT01183637",
      "title": "Evaluation of an Acellular Osteochondral Graft for Cartilage LEsions Pilot Trial",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Articular Cartilage Injury"
      ],
      "interventions": [
        {
          "name": "Kensey Nash Corp. Cartilage Repair Device",
          "type": "DEVICE"
        },
        {
          "name": "Microfracture",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Kensey Nash Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2010-06",
      "completion_date": "2014-05",
      "has_results": false,
      "last_update_posted_date": "2015-05-25",
      "last_synced_at": "2026-07-22T16:09:16.099Z",
      "location_count": 2,
      "location_summary": "Salisbury, Maryland • Kirkwood, Missouri",
      "locations": [
        {
          "city": "Salisbury",
          "state": "Maryland"
        },
        {
          "city": "Kirkwood",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01183637"
    },
    {
      "nct_id": "NCT01957722",
      "title": "NOVOCART®3D for Treatment of Articular Cartilage of the Knee",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Articular Cartilage of the Femoral Condyle Between 2-6cm2"
      ],
      "interventions": [
        {
          "name": "Microfracture",
          "type": "PROCEDURE"
        },
        {
          "name": "NOVOCART 3D",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BIOLOGICAL"
      ],
      "sponsor": "Aesculap Biologics, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 233,
      "start_date": "2013-12",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2025-03-21",
      "last_synced_at": "2026-07-22T16:09:16.099Z",
      "location_count": 30,
      "location_summary": "La Mesa, California • Los Angeles, California • Redwood City, California + 26 more",
      "locations": [
        {
          "city": "La Mesa",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Redwood City",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Steamboat Springs",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01957722"
    }
  ]
}