{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Articular+Cartilage&page=4",
    "query": {
      "condition": "Articular Cartilage",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 102,
    "total_pages": 11,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Articular+Cartilage&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Articular+Cartilage&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-15T09:19:59.786Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07766720",
      "title": "Effects of Eggshell Membrane and Curcumin Extract Supplementation, Separately or Combined, on Recovery From Intense Exercise",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Exercise-induced Muscle Soreness",
        "Exercise-induced Joint Pain",
        "Exercise-induced Joint Stiffness",
        "Exercise-induced Cartilage Turnover"
      ],
      "interventions": [
        {
          "name": "NEM® brand eggshell membrane powder",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "curQ+® brand highly absorbable curcumin",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "EM Placebo",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Curc Placebo",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "NEM® plus curQ+® combination",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "ESM Technologies, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "MALE",
        "summary": "18 Years to 40 Years · Male only"
      },
      "enrollment_count": 60,
      "start_date": "2026-02-01",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-14",
      "last_synced_at": "2026-11-15T09:19:59.786Z",
      "location_count": 1,
      "location_summary": "College Station, Texas",
      "locations": [
        {
          "city": "College Station",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07766720"
    },
    {
      "nct_id": "NCT07909928",
      "title": "Biologic Augmentation of Osteochondral Allograft Transplantation in the Knee",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteochondral Defect",
        "Articular Cartilage Defect"
      ],
      "interventions": [
        {
          "name": "Biologically Augmented Osteochondral Allograft Transplantation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2026-11-20",
      "completion_date": "2028-07-20",
      "has_results": false,
      "last_update_posted_date": "2026-11-02",
      "last_synced_at": "2026-11-15T09:19:59.786Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07909928"
    },
    {
      "nct_id": "NCT01670617",
      "title": "DeNovo NT Natural Tissue Graft Stratified Knee Study",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Defect of Articular Cartilage",
        "Knee Injuries"
      ],
      "interventions": [
        {
          "name": "Particulated Juvenile Articular Cartilage",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Zimmer Orthobiologics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 90,
      "start_date": "2012-03",
      "completion_date": "2021-12",
      "has_results": false,
      "last_update_posted_date": "2017-01-26",
      "last_synced_at": "2026-11-15T09:19:59.786Z",
      "location_count": 16,
      "location_summary": "Los Angeles, California • San Deigo, California • Aurora, Colorado + 13 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Deigo",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Gulf Breeze",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01670617"
    },
    {
      "nct_id": "NCT02090140",
      "title": "Microfracture Versus Adipose Derived Stem Cells for the Treatment of Articular Cartilage Defects",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Lesion of Articular Cartilage of Knee"
      ],
      "interventions": [
        {
          "name": "ADSC Application",
          "type": "PROCEDURE"
        },
        {
          "name": "Microfracture",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 17,
      "start_date": "2015-11",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2024-04-25",
      "last_synced_at": "2026-11-15T09:19:59.786Z",
      "location_count": 3,
      "location_summary": "Redwood City, California • Santa Monica, California • Denver, Colorado",
      "locations": [
        {
          "city": "Redwood City",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02090140"
    },
    {
      "nct_id": "NCT01434966",
      "title": "Changes in Quadriceps Function Following Local or Distant Interventions in Individuals With Patellofemoral Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patellofemoral Pain Syndrome",
        "Chondromalacia Patellae",
        "Anterior Knee Pain Syndrome"
      ],
      "interventions": [
        {
          "name": "Lumbopelvic Manipulation",
          "type": "OTHER"
        },
        {
          "name": "TENS- Spine",
          "type": "OTHER"
        },
        {
          "name": "TENS- Knee",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Creighton University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "15 Years to 50 Years"
      },
      "enrollment_count": 47,
      "start_date": "2011-09",
      "completion_date": "2015-07",
      "has_results": false,
      "last_update_posted_date": "2015-12-14",
      "last_synced_at": "2026-11-15T09:19:59.786Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01434966"
    },
    {
      "nct_id": "NCT04730557",
      "title": "Reducing Obesity and Cartilage Compression in Knees",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Osteoarthritis",
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Weight Loss",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 88,
      "start_date": "2020-06-05",
      "completion_date": "2024-05-17",
      "has_results": false,
      "last_update_posted_date": "2024-06-06",
      "last_synced_at": "2026-11-15T09:19:59.786Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04730557"
    },
    {
      "nct_id": "NCT01256788",
      "title": "Post-op Treatment With Hyaluronic Acid Injections",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Meniscus Tear",
        "Chondropathy/Degenerative Joint Disease (DJD)"
      ],
      "interventions": [
        {
          "name": "Euflexxa",
          "type": "DEVICE"
        },
        {
          "name": "Saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "The Hawkins Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2010-09",
      "completion_date": "2014-04",
      "has_results": true,
      "last_update_posted_date": "2019-01-08",
      "last_synced_at": "2026-11-15T09:19:59.786Z",
      "location_count": 1,
      "location_summary": "Greenville, South Carolina",
      "locations": [
        {
          "city": "Greenville",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01256788"
    },
    {
      "nct_id": "NCT07709819",
      "title": "A Nanoscopic Second Look Into the Knee Joint",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Meniscal Tears"
      ],
      "interventions": [
        {
          "name": "Nanoscopic Arthroscopy of the Knee",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Angelina Vera MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2026-05-20",
      "completion_date": "2029-05-20",
      "has_results": false,
      "last_update_posted_date": "2026-07-17",
      "last_synced_at": "2026-11-15T09:19:59.786Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07709819"
    },
    {
      "nct_id": "NCT06792539",
      "title": "Evaluate the Safety and Effectiveness of the Polymotion Hip Resurfacing (PHR) System Compared to Total Hip Arthroplasty",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis of the Hip",
        "Degenerative Joint Disease of Hip",
        "Dysplasia; Hip"
      ],
      "interventions": [
        {
          "name": "Polymotion Hip Resurfacing (PHR) System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "JointMedica Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 238,
      "start_date": "2025-01-22",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2026-05-01",
      "last_synced_at": "2026-11-15T09:19:59.786Z",
      "location_count": 8,
      "location_summary": "Tampa, Florida • Chicago, Illinois • Baltimore, Maryland + 5 more",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New Albany",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06792539"
    },
    {
      "nct_id": "NCT05082831",
      "title": "Human ECM Implanted Within Microfracture Interstices & the Cartilage Defect in the Knee to Regenerate Hyaline Cartilage",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Articular Cartilage Disorder of Knee",
        "Cartilage Damage",
        "Microfractures"
      ],
      "interventions": [
        {
          "name": "microfracture surgery + HST003",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Histogen",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 1,
      "start_date": "2021-11-15",
      "completion_date": "2023-01-16",
      "has_results": false,
      "last_update_posted_date": "2023-01-19",
      "last_synced_at": "2026-11-15T09:19:59.786Z",
      "location_count": 5,
      "location_summary": "Vail, Colorado • Bradenton, Florida • Bethesda, Maryland + 2 more",
      "locations": [
        {
          "city": "Vail",
          "state": "Colorado"
        },
        {
          "city": "Bradenton",
          "state": "Florida"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "State College",
          "state": "Pennsylvania"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05082831"
    }
  ]
}