{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Asthenopia",
    "query": {
      "condition": "Asthenopia"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 20,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Asthenopia&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T05:48:03.070Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00585026",
      "title": "Randomized Clinical Trial of Bifocal Lenses Versus Computer-specific Progressive Addition Lenses",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Refractive Error",
        "Presbyopia",
        "Asthenopia",
        "Eyeglasses"
      ],
      "interventions": [
        {
          "name": "D-28 bifocal lenses and frame",
          "type": "DEVICE"
        },
        {
          "name": "Progressive addition computer lenses and frame",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2006-10",
      "completion_date": "2007-06",
      "has_results": false,
      "last_update_posted_date": "2011-06-15",
      "last_synced_at": "2026-07-23T05:48:03.070Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00585026"
    },
    {
      "nct_id": "NCT03585790",
      "title": "The Impact of Soft Contact Lens Attributes on Symptoms Associated With Digital Eye Strain in Symptomatic Soft Contact Lens Wearers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Asthenopia",
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Contact lens with Multifocal Optics",
          "type": "DEVICE"
        },
        {
          "name": "Contact lens with Single Vision Optics",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Pete Kollbaum, OD, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 45,
      "start_date": "2018-09-13",
      "completion_date": "2018-11-02",
      "has_results": true,
      "last_update_posted_date": "2020-01-07",
      "last_synced_at": "2026-07-23T05:48:03.070Z",
      "location_count": 1,
      "location_summary": "Bloomington, Indiana",
      "locations": [
        {
          "city": "Bloomington",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03585790"
    },
    {
      "nct_id": "NCT01857102",
      "title": "Toric Eye Strain and Stability Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "etafilcon A",
          "type": "DEVICE"
        },
        {
          "name": "etafilcon A for Astigmatism",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Vision Care, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 159,
      "start_date": "2013-09",
      "completion_date": "2014-06",
      "has_results": true,
      "last_update_posted_date": "2018-06-19",
      "last_synced_at": "2026-07-23T05:48:03.070Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01857102"
    },
    {
      "nct_id": "NCT04013789",
      "title": "Comparison of Two Daily Disposable Lenses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Ametropia",
        "Myopia"
      ],
      "interventions": [
        {
          "name": "DACP FreshTech contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "DACP contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 79,
      "start_date": "2019-08-27",
      "completion_date": "2019-11-22",
      "has_results": true,
      "last_update_posted_date": "2020-11-24",
      "last_synced_at": "2026-07-23T05:48:03.070Z",
      "location_count": 1,
      "location_summary": "Bloomington, Indiana",
      "locations": [
        {
          "city": "Bloomington",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04013789"
    },
    {
      "nct_id": "NCT03054597",
      "title": "Use of Eye Exercises to Improve Vision",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Eye Strain"
      ],
      "interventions": [
        {
          "name": "Circular light motion",
          "type": "DEVICE"
        },
        {
          "name": "Diagonal light motion",
          "type": "DEVICE"
        },
        {
          "name": "Peripheral light motion",
          "type": "DEVICE"
        },
        {
          "name": "Exercise",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 19,
      "start_date": "2012-02",
      "completion_date": "2012-04",
      "has_results": false,
      "last_update_posted_date": "2017-10-06",
      "last_synced_at": "2026-07-23T05:48:03.070Z",
      "location_count": 1,
      "location_summary": "Fremont, California",
      "locations": [
        {
          "city": "Fremont",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03054597"
    },
    {
      "nct_id": "NCT04775654",
      "title": "The Effects of Blackcurrant Supplementation on Eye Health",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Eye Strain",
        "Eye Fatigue"
      ],
      "interventions": [
        {
          "name": "Blackcurrant",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Nutraceuticals Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "30 Years to 60 Years · Female only"
      },
      "enrollment_count": 57,
      "start_date": "2021-03-01",
      "completion_date": "2021-12-31",
      "has_results": false,
      "last_update_posted_date": "2022-01-24",
      "last_synced_at": "2026-07-23T05:48:03.070Z",
      "location_count": 1,
      "location_summary": "Franklin, Tennessee",
      "locations": [
        {
          "city": "Franklin",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04775654"
    },
    {
      "nct_id": "NCT07123584",
      "title": "A Randomized Controlled Trial to Evaluate the Safety and Efficacy of an Oral Supplement in Supporting Vision and Eye Health",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dry Eye",
        "Eye Fatigue"
      ],
      "interventions": [
        {
          "name": "Eye Empower",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Bio Nature Health",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "45 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2024-11-06",
      "completion_date": "2024-12-30",
      "has_results": false,
      "last_update_posted_date": "2025-08-14",
      "last_synced_at": "2026-07-23T05:48:03.070Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07123584"
    },
    {
      "nct_id": "NCT00318045",
      "title": "Effects of Optical Blur on Performance and Comfort of Computer Users",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Refractive Error"
      ],
      "interventions": [
        {
          "name": "Eyeglass lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vision Council of America",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 35,
      "start_date": "2005-10",
      "completion_date": "2006-04",
      "has_results": false,
      "last_update_posted_date": "2006-04-25",
      "last_synced_at": "2026-07-23T05:48:03.070Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00318045"
    },
    {
      "nct_id": "NCT00785135",
      "title": "Effects of Prismatic Spectacle Lenses on Symptoms of Dizziness, Headache and Anxiety as Caused by Vertical Heterophoria",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Binocular Dysfunction",
        "Vertical Heterophoria",
        "Vision, Binocular",
        "Vision Disparity"
      ],
      "interventions": [
        {
          "name": "Lenses containing prismatic correction",
          "type": "DEVICE"
        },
        {
          "name": "Lenses not containing prismatic correction",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Vision Specialists of Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "14 Years and older"
      },
      "enrollment_count": 13,
      "start_date": "2008-11",
      "completion_date": "2015-11",
      "has_results": false,
      "last_update_posted_date": "2020-10-12",
      "last_synced_at": "2026-07-23T05:48:03.070Z",
      "location_count": 1,
      "location_summary": "Birmingham, Michigan",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00785135"
    },
    {
      "nct_id": "NCT05895500",
      "title": "Evaluate the Safety and Efficacy of Calcitonin Gene-Related Peptide (CGRP) Antagonists in Patients With Dry Eye Disease and Asthenopia",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dry Eye",
        "Asthenopia"
      ],
      "interventions": [
        {
          "name": "Injection for SC administration (120mg/syringe)",
          "type": "DRUG"
        },
        {
          "name": "Tablet (50mg/tablet), oral",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Nvision Laser Eye Centers",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 103,
      "start_date": "2023-05-10",
      "completion_date": "2023-11-09",
      "has_results": false,
      "last_update_posted_date": "2024-06-03",
      "last_synced_at": "2026-07-23T05:48:03.070Z",
      "location_count": 1,
      "location_summary": "Torrance, California",
      "locations": [
        {
          "city": "Torrance",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05895500"
    }
  ]
}