{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Atrial+Enlargement", "query": { "condition": "Atrial Enlargement" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 11, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Atrial+Enlargement&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-05-22T04:13:44.154Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04056715", "title": "Extended ECG Monitoring in HCM Patients", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Hypertrophic Cardiomyopathy", "Nonsustained Ventricular Tachycardia", "Ventricular Tachycardia", "Atrial Fibrillation", "Arrhythmia" ], "interventions": [ { "name": "Zio XT", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "iRhythm Technologies, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 250, "start_date": "2020-01-14", "completion_date": "2022-04-18", "has_results": false, "last_update_posted_date": "2023-03-01", "last_synced_at": "2026-05-22T04:13:44.154Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04056715" }, { "nct_id": "NCT01630408", "title": "The Effects of Active VItamin D on Left Atrial Volume Index", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Heart Failure" ], "interventions": [ { "name": "Paricalcitol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 0, "start_date": "2014-03", "completion_date": "2014-06", "has_results": false, "last_update_posted_date": "2013-08-16", "last_synced_at": "2026-05-22T04:13:44.154Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01630408" }, { "nct_id": "NCT03327623", "title": "Sleep Apnea and Hypertrophic Cardiomyopathy (HCM)", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Hypertrophic Cardiomyopathy" ], "interventions": [], "intervention_types": [], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 290, "start_date": "2017-11-13", "completion_date": "2024-06-21", "has_results": false, "last_update_posted_date": "2025-03-26", "last_synced_at": "2026-05-22T04:13:44.154Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT03327623" }, { "nct_id": "NCT06763549", "title": "COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Cardiopulmonary Failure", "Myocardial Infarction (MI)", "Heart Decompensation", "Heart Failure", "HFrEF - Heart Failure with Reduced Ejection Fraction", "HFpEF - Heart Failure with Preserved Ejection Fraction", "Syncopation", "Syncope", "Ischemic Cardiovascular Disease", "STEMI", "STEMI (ST Elevation MI)", "Atrial Fibrillation (AF)", "Atrial Enlargement", "LVF", "Conduction Defect", "Conduction Abnormalities", "Heart Block", "Valvular Diseases", "Cardiac Output, Low", "Stroke Volume", "Stroke Volume Variation", "Hyperkalemia", "Hypercalcemia", "Hypocalcemia", "LV Dysfunction", "QT Prolongation", "Sudden Cardiac Death Due to Cardiac Arrhythmia", "Ventricular Arrhythmia", "Pacing", "Pacing Induced Dyssynchrony", "Silent Ischemia", "Pericarditis", "Sleep Related Breathing Disorder", "RSA", "Apnea, Obstructive", "Cardiac Output Measurement", "Respiratory Impedance", "CRT And/or ICD", "Infarction", "Cardiomyopathies, Primary", "Hypertrophy" ], "interventions": [ { "name": "SUBPROTOCOL A", "type": "DEVICE" }, { "name": "SUBPROTOCOL B", "type": "DEVICE" }, { "name": "SUBPROTOCOL C", "type": "DEVICE" }, { "name": "SUBPROTOCOL D", "type": "DEVICE" }, { "name": "SUBPROTOCOL E", "type": "DEVICE" }, { "name": "SUBPROTOCOL F", "type": "DEVICE" }, { "name": "SUBPROTOCOL G", "type": "DEVICE" }, { "name": "SUBPROTOCOL H", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Peerbridge Health, Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 15000, "start_date": "2024-11-16", "completion_date": "2026-04-15", "has_results": false, "last_update_posted_date": "2025-01-08", "last_synced_at": "2026-05-22T04:13:44.154Z", "location_count": 1, "location_summary": "Melbourne, Florida", "locations": [ { "city": "Melbourne", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT06763549" }, { "nct_id": "NCT01198873", "title": "Effects of Dronedarone on Cardiac Geometry and Function in Patients With Atrial Fibrillation and Left Atrial Enlargement", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Atrial Fibrillation" ], "interventions": [ { "name": "Dronedarone", "type": "DRUG" }, { "name": "Placebo (for Dronedarone)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sanofi", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 76, "start_date": "2010-09", "completion_date": "2012-01", "has_results": true, "last_update_posted_date": "2013-02-12", "last_synced_at": "2026-05-22T04:13:44.154Z", "location_count": 56, "location_summary": "Phoenix, Arizona • Little Rock, Arkansas • Beverly Hills, California + 51 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Beverly Hills", "state": "California" }, { "city": "Loma Linda", "state": "California" }, { "city": "Merced", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01198873" }, { "nct_id": "NCT04112290", "title": "A Prospective Incident Study of Arrhythmias in Hypertrophic Cardiomyopathy", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Hypertrophic Cardiomyopathy" ], "interventions": [], "intervention_types": [], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 260, "start_date": "2019-11-05", "completion_date": "2027-12", "has_results": false, "last_update_posted_date": "2026-02-05", "last_synced_at": "2026-05-22T04:13:44.154Z", "location_count": 1, "location_summary": "Rochester, Minnesota", "locations": [ { "city": "Rochester", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT04112290" }, { "nct_id": "NCT00074880", "title": "The Role of Heart Stiff and Weak Atrium on Exercise Capacity in Patients With Hypertrophic Cardiomyopathy", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Cardiomyopathy, Hypertrophic" ], "interventions": [], "intervention_types": [], "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 50, "start_date": "2003-12", "completion_date": "2005-03", "has_results": false, "last_update_posted_date": "2008-03-04", "last_synced_at": "2026-05-22T04:13:44.154Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00074880" }, { "nct_id": "NCT06699056", "title": "AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Ventricular Ejection Fraction", "LVF", "LV Dysfunction", "Atrial Enlargement", "Conduction Defect", "Heart Failure", "Valvular Heart Disease", "Ischemic Heart Disease", "Cardiotoxicity", "Myocardial Infarction", "Dilated Cardiomyopathy", "HFrEF - Heart Failure With Reduced Ejection Fraction", "HFpEF - Heart Failure With Preserved Ejection Fraction", "Syncope", "Remodeling, Cardiac" ], "interventions": [ { "name": "15-minutes of sitting during COR ECG Acquistion", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Peerbridge Health, Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1500, "start_date": "2024-11-21", "completion_date": "2025-09", "has_results": false, "last_update_posted_date": "2025-02-11", "last_synced_at": "2026-05-22T04:13:44.154Z", "location_count": 8, "location_summary": "Orange, California • Melbourne, Florida • Detroit, Michigan + 5 more", "locations": [ { "city": "Orange", "state": "California" }, { "city": "Melbourne", "state": "Florida" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Hackensack", "state": "New Jersey" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT06699056" }, { "nct_id": "NCT01695564", "title": "Safety and Efficacy of Left Atrial Appendage Occlusion Devices", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Atrial Fibrillation" ], "interventions": [ { "name": "LARIAT LAA", "type": "DEVICE" }, { "name": "WATCHMAN", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Kansas City Heart Rhythm Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 169, "start_date": "2012-05", "completion_date": "2018-02", "has_results": false, "last_update_posted_date": "2019-05-02", "last_synced_at": "2026-05-22T04:13:44.154Z", "location_count": 1, "location_summary": "Kansas City, Kansas", "locations": [ { "city": "Kansas City", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01695564" }, { "nct_id": "NCT04752293", "title": "Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Hypertension", "Left Ventricular Hypertrophy", "Left Ventricular Dysfunction", "Left Atrial Dilatation", "Left Ventricular Diastolic Dysfunction", "Kidney Diseases", "Kidney Injury", "Kidney Dysfunction", "Sodium Urine High", "Blood Pressure Disorders", "Uric Acid Retention", "Angiotensin Hypertension", "Autonomic Dysfunction", "Autonomic Imbalance", "Pediatric Kidney Disease", "Pediatric Obesity", "Proteinuria", "Albuminuria" ], "interventions": [], "intervention_types": [], "sponsor": "Wake Forest University Health Sciences", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "7 Years", "maximum_age": "18 Years", "sex": "ALL", "summary": "7 Years to 18 Years" }, "enrollment_count": 125, "start_date": "2021-05-19", "completion_date": "2026-12", "has_results": false, "last_update_posted_date": "2025-12-11", "last_synced_at": "2026-05-22T04:13:44.154Z", "location_count": 1, "location_summary": "Winston-Salem, North Carolina", "locations": [ { "city": "Winston-Salem", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT04752293" } ] }