{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Autonomic+Dysfunction&page=9",
    "query": {
      "condition": "Autonomic Dysfunction",
      "page": 9
    },
    "page_size": 10
  },
  "pagination": {
    "page": 9,
    "page_size": 10,
    "total_count": 519,
    "total_pages": 52,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Autonomic+Dysfunction&page=10&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Autonomic+Dysfunction&page=8&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-21T17:36:40.972Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05041387",
      "title": "Data Collection of Standard Care of Patients in the EMG Section",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neuropathy",
        "Muscle Disorders",
        "Dysautonomia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "110 Years",
        "sex": "ALL",
        "summary": "18 Years to 110 Years"
      },
      "enrollment_count": 200,
      "start_date": "2024-06-24",
      "completion_date": "2031-05-01",
      "has_results": false,
      "last_update_posted_date": "2026-09-14",
      "last_synced_at": "2026-10-21T17:36:40.972Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05041387"
    },
    {
      "nct_id": "NCT03446807",
      "title": "Safety and Efficacy of Droxidopa for Fatigue in Patients With Parkinsonism",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Parkinson Disease",
        "Multiple System Atrophy",
        "Progressive Supranuclear Palsy"
      ],
      "interventions": [
        {
          "name": "Droxidopa",
          "type": "DRUG"
        },
        {
          "name": "Placebo Oral Tablet",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2021-12",
      "completion_date": "2023-07-01",
      "has_results": false,
      "last_update_posted_date": "2022-03-02",
      "last_synced_at": "2026-10-21T17:36:40.972Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03446807"
    },
    {
      "nct_id": "NCT00742521",
      "title": "Mechanisms of Hypoglycemia Associated Autonomic Dysfunction, Q.3",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Type 1 Diabetes"
      ],
      "interventions": [
        {
          "name": "glucose clamp",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 22,
      "start_date": "2001-03",
      "completion_date": "2009-06",
      "has_results": false,
      "last_update_posted_date": "2015-06-10",
      "last_synced_at": "2026-10-21T17:36:40.972Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00742521"
    },
    {
      "nct_id": "NCT00613106",
      "title": "Double-Blind Follow-on Safety Study of HZT-501 (Ibuprofen 800 mg/Famotidine 26.6 mg) in Subjects Who Have Completed Participation in HZ-CA-301 (NCT00450658) or HZ-CA-303 (NCT00450216)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Osteoarthritis",
        "Rheumatoid Arthritis",
        "Chronic Low Back Pain",
        "Chronic Regional Pain Syndrome",
        "Chronic Soft Tissue Pain"
      ],
      "interventions": [
        {
          "name": "HZT-501",
          "type": "DRUG"
        },
        {
          "name": "Ibuprofen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Amgen",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "81 Years",
        "sex": "ALL",
        "summary": "40 Years to 81 Years"
      },
      "enrollment_count": 179,
      "start_date": "2007-09",
      "completion_date": "2008-10",
      "has_results": true,
      "last_update_posted_date": "2024-12-17",
      "last_synced_at": "2026-10-21T17:36:40.972Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00613106"
    },
    {
      "nct_id": "NCT00001549",
      "title": "Diagnosis and Natural History Study of Patients With Neurological Conditions",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer's Disease",
        "Dementia",
        "Movement Disorder",
        "Multiple System Atrophy",
        "Parkinson's Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 600,
      "start_date": "1995-10",
      "completion_date": "2006-01",
      "has_results": false,
      "last_update_posted_date": "2008-03-04",
      "last_synced_at": "2026-10-21T17:36:40.972Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001549"
    },
    {
      "nct_id": "NCT01512121",
      "title": "Spinal Cord Stimulation and Functional MRI",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Complex Regional Pain Syndrome (CRPS)",
        "Neuropathic Leg Pain"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Vibhor Krishna",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 10,
      "start_date": "2011-09",
      "completion_date": "2017-08",
      "has_results": false,
      "last_update_posted_date": "2019-09-23",
      "last_synced_at": "2026-10-21T17:36:40.972Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01512121"
    },
    {
      "nct_id": "NCT06616363",
      "title": "Does a Periaqueductal Gray-vagus Nerve Interface Malfunction Explain the Nat hx With Its Numerous Co-morbidities?",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "POTS - Postural Orthostatic Tachycardia Syndrome"
      ],
      "interventions": [
        {
          "name": "Questionnaires to be competed",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Provide list of medication and lifetime events",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Use phone App to record new life events",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Will wear an activity monitor",
          "type": "DEVICE"
        },
        {
          "name": "Periodic 24-hour urine sodium check",
          "type": "OTHER"
        },
        {
          "name": "A fMRI scan",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "A bedside tilt test will be performed",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "IV placed to collect blood samples",
          "type": "OTHER"
        },
        {
          "name": "Stool Sample",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DEVICE",
        "OTHER",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "21 Years",
        "sex": "FEMALE",
        "summary": "12 Years to 21 Years · Female only"
      },
      "enrollment_count": 120,
      "start_date": "2024-05-29",
      "completion_date": "2028-07",
      "has_results": false,
      "last_update_posted_date": "2026-09-29",
      "last_synced_at": "2026-10-21T17:36:40.972Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06616363"
    },
    {
      "nct_id": "NCT07238465",
      "title": "Exploring Sympathetic Nervous System Function in Individuals With Down Syndrome",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Down Syndrome",
        "Autonomic Dysfunction"
      ],
      "interventions": [
        {
          "name": "Cold Stress",
          "type": "OTHER"
        },
        {
          "name": "Maximal Dynamic Exercise",
          "type": "OTHER"
        },
        {
          "name": "Isometric Handgrip Exercise with Post-Exercise Muscle Ischemia",
          "type": "OTHER"
        },
        {
          "name": "Head-up Tilt Table Test",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 200,
      "start_date": "2026-04-06",
      "completion_date": "2030-12",
      "has_results": false,
      "last_update_posted_date": "2026-10-13",
      "last_synced_at": "2026-10-21T17:36:40.972Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07238465"
    },
    {
      "nct_id": "NCT02800863",
      "title": "TARGET Post-Approval Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Complex Regional Pain Syndrome (CRPS)"
      ],
      "interventions": [
        {
          "name": "Dorsal Root Ganglion (DRG) Stimulation (Axium™ Neurostimulator System)",
          "type": "DEVICE"
        },
        {
          "name": "Dorsal Root Ganglion (DRG) Stimulation (Proclaim™ Neurostimulator System)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "22 Years to 75 Years"
      },
      "enrollment_count": 426,
      "start_date": "2016-08-23",
      "completion_date": "2021-09-23",
      "has_results": true,
      "last_update_posted_date": "2024-07-08",
      "last_synced_at": "2026-10-21T17:36:40.972Z",
      "location_count": 44,
      "location_summary": "Scottsdale, Arizona • Camarillo, California • Larkspur, California + 38 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Camarillo",
          "state": "California"
        },
        {
          "city": "Larkspur",
          "state": "California"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02800863"
    },
    {
      "nct_id": "NCT05989763",
      "title": "Interrogating the Pathophysiological Mechanisms of Constipation in Patients With Systemic Sclerosis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Systemic Sclerosis",
        "Constipation",
        "Gastrointestinal Motility Disorder",
        "Autonomic Dysfunction"
      ],
      "interventions": [
        {
          "name": "Transcutaneous Electrical Acustimulation (TEA)",
          "type": "DEVICE"
        },
        {
          "name": "Sham-TEA",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2024-02-17",
      "completion_date": "2029-09-01",
      "has_results": false,
      "last_update_posted_date": "2025-06-26",
      "last_synced_at": "2026-10-21T17:36:40.972Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05989763"
    }
  ]
}