{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Autonomic+Imbalance",
    "query": {
      "condition": "Autonomic Imbalance"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 19,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Autonomic+Imbalance&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T02:10:18.363Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02958176",
      "title": "Heart Rate Variability Biofeedback for Female Sexual Arousal Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Female Sexual Arousal Disorder"
      ],
      "interventions": [
        {
          "name": "HRV Biofeedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Autogenic Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Texas at Austin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 40 Years · Female only"
      },
      "enrollment_count": 65,
      "start_date": "2016-10",
      "completion_date": "2018-01",
      "has_results": false,
      "last_update_posted_date": "2018-10-11",
      "last_synced_at": "2026-05-22T02:10:18.363Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02958176"
    },
    {
      "nct_id": "NCT04858178",
      "title": "Transcutaneous Spinal Cord Neuromodulation to Normalize Autonomic Phenotypes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injuries",
        "Autonomic Imbalance",
        "Autonomic Dysreflexia",
        "Orthostatic; Hypotension, Neurogenic"
      ],
      "interventions": [
        {
          "name": "Tests of sympathetic inhibition",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Tests of sympathetic activation",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Testing of autonomic dysreflexia",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Transcutaneous spinal cord stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "DEVICE"
      ],
      "sponsor": "Spaulding Rehabilitation Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 4,
      "start_date": "2022-02-17",
      "completion_date": "2022-11-14",
      "has_results": false,
      "last_update_posted_date": "2023-04-14",
      "last_synced_at": "2026-05-22T02:10:18.363Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04858178"
    },
    {
      "nct_id": "NCT04493372",
      "title": "Deciphering Preserved Autonomic Function After Spinal Cord Injury",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injuries",
        "Autonomic Imbalance",
        "Autonomic Dysreflexia",
        "Orthostatic Hypotension"
      ],
      "interventions": [
        {
          "name": "Tests of sympathetic inhibition",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Tests of sympathetic activation",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Testing of autonomic dysreflexia",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 69,
      "start_date": "2020-11-13",
      "completion_date": "2026-09-08",
      "has_results": false,
      "last_update_posted_date": "2026-05-01",
      "last_synced_at": "2026-05-22T02:10:18.363Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04493372"
    },
    {
      "nct_id": "NCT04233606",
      "title": "Influence of Osmotic Stimulation of Vasopressin on Autonomic Function",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Water Stress",
        "Body Water Dehydration"
      ],
      "interventions": [
        {
          "name": "Hypertonic Saline",
          "type": "OTHER"
        },
        {
          "name": "Normal Saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Greensboro",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 0,
      "start_date": "2023-11",
      "completion_date": "2024-07",
      "has_results": false,
      "last_update_posted_date": "2023-11-13",
      "last_synced_at": "2026-05-22T02:10:18.363Z",
      "location_count": 1,
      "location_summary": "Greensboro, North Carolina",
      "locations": [
        {
          "city": "Greensboro",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04233606"
    },
    {
      "nct_id": "NCT04100486",
      "title": "Non-Invasive Bioelectronic Analytics",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Autonomic Dysfunction",
        "Autonomic Imbalance",
        "Autonomic Nervous System Diseases",
        "Vagus Nerve Autonomic Disorder"
      ],
      "interventions": [
        {
          "name": "Standing-Squatting-Standing Test",
          "type": "OTHER"
        },
        {
          "name": "Deep Breathing Test",
          "type": "OTHER"
        },
        {
          "name": "Cold Pressor Test",
          "type": "OTHER"
        },
        {
          "name": "Cold Face Test",
          "type": "OTHER"
        },
        {
          "name": "Valsalva Maneuver",
          "type": "OTHER"
        },
        {
          "name": "Transcutaneous Auricular Vagus Nerve Stimulation (taVNS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Northwell Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 48,
      "start_date": "2019-08-29",
      "completion_date": "2025-09",
      "has_results": false,
      "last_update_posted_date": "2025-05-31",
      "last_synced_at": "2026-05-22T02:10:18.363Z",
      "location_count": 1,
      "location_summary": "Manhasset, New York",
      "locations": [
        {
          "city": "Manhasset",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04100486"
    },
    {
      "nct_id": "NCT04428619",
      "title": "Percutaneous Electrical Nerve Field Stimulation for Adults With Irritable Bowel Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Irritable Bowel Syndrome",
        "Abdominal Pain",
        "Autonomic Nervous System Imbalance"
      ],
      "interventions": [
        {
          "name": "Peripheral Electrical Nerve Field Stimulation (PENFS) Device",
          "type": "DEVICE"
        },
        {
          "name": "Sham Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 15,
      "start_date": "2020-08-01",
      "completion_date": "2023-02-14",
      "has_results": true,
      "last_update_posted_date": "2025-05-16",
      "last_synced_at": "2026-05-22T02:10:18.363Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04428619"
    },
    {
      "nct_id": "NCT03992378",
      "title": "Neuromodulation to Regulate Inflammation and Autonomic Imbalance in Sepsis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Septic Shock"
      ],
      "interventions": [
        {
          "name": "Low Level Transcutaneous Vagus Nerve Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2019-10-10",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-04-01",
      "last_synced_at": "2026-05-22T02:10:18.363Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03992378"
    },
    {
      "nct_id": "NCT05190731",
      "title": "Alterations in Bioelectric Activity at Acupuncture Points Following CV4 Cranial Manipulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autonomic Imbalance"
      ],
      "interventions": [
        {
          "name": "Osteopathic cranial manipulative medicine",
          "type": "OTHER"
        },
        {
          "name": "Sham",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Jan T Hendryx",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "78 Years",
        "sex": "ALL",
        "summary": "18 Years to 78 Years"
      },
      "enrollment_count": 77,
      "start_date": "2017-11-10",
      "completion_date": "2018-11-07",
      "has_results": false,
      "last_update_posted_date": "2022-04-22",
      "last_synced_at": "2026-05-22T02:10:18.363Z",
      "location_count": 1,
      "location_summary": "Erie, Pennsylvania",
      "locations": [
        {
          "city": "Erie",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05190731"
    },
    {
      "nct_id": "NCT00060866",
      "title": "Propranolol to Treat Fainting Due to Sympathoadrenal Imbalance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Neurocardiogenic Syncope"
      ],
      "interventions": [
        {
          "name": "Propranolol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 24,
      "start_date": "2003-05",
      "completion_date": "2005-03",
      "has_results": false,
      "last_update_posted_date": "2008-03-04",
      "last_synced_at": "2026-05-22T02:10:18.363Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00060866"
    },
    {
      "nct_id": "NCT03362944",
      "title": "Active and Passive Music Therapy Interventions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autonomic Nervous System Imbalance",
        "Hypothalamic Pituitary Adrenal Axis Suppression"
      ],
      "interventions": [
        {
          "name": "Active Music Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Passive Music Therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "34 Years",
        "sex": "ALL",
        "summary": "18 Years to 34 Years"
      },
      "enrollment_count": 16,
      "start_date": "2017-11-20",
      "completion_date": "2017-12-18",
      "has_results": true,
      "last_update_posted_date": "2019-06-05",
      "last_synced_at": "2026-05-22T02:10:18.363Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03362944"
    }
  ]
}