{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Avascular+Necrosis+of+Bone",
    "query": {
      "condition": "Avascular Necrosis of Bone"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 111,
    "total_pages": 12,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Avascular+Necrosis+of+Bone&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:05:15.499Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03969654",
      "title": "ROSA Robot Used in Total Knee Replacement Post Market Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Knee Pain",
        "Chronic Osteoarthritis",
        "Avascular Necrosis of the Femoral Condyle",
        "Moderate Varus, Valgus or Flexion Deformities",
        "Rheumatoid Arthritis"
      ],
      "interventions": [
        {
          "name": "PERSONA Total Knee",
          "type": "DEVICE"
        },
        {
          "name": "Vanguard Total Knee",
          "type": "DEVICE"
        },
        {
          "name": "NexGen Total Knee",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 181,
      "start_date": "2020-05-01",
      "completion_date": "2023-09-22",
      "has_results": true,
      "last_update_posted_date": "2024-05-03",
      "last_synced_at": "2026-05-22T09:05:15.499Z",
      "location_count": 5,
      "location_summary": "Vail, Colorado • Westminster, Colorado • Springfield, Illinois + 2 more",
      "locations": [
        {
          "city": "Vail",
          "state": "Colorado"
        },
        {
          "city": "Westminster",
          "state": "Colorado"
        },
        {
          "city": "Springfield",
          "state": "Illinois"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "North Chesterfield",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03969654"
    },
    {
      "nct_id": "NCT00412841",
      "title": "Atorvastatin to Prevent Avascular Necrosis of Bone in Steroid Treated Exacerbated Systemic Lupus Erythematosus",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Avascular Necrosis"
      ],
      "interventions": [
        {
          "name": "Atorvastatin",
          "type": "DRUG"
        },
        {
          "name": "MRI, Venipuncture",
          "type": "PROCEDURE"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 75 Years · Female only"
      },
      "enrollment_count": 43,
      "start_date": "2002-11",
      "completion_date": "2008-01",
      "has_results": true,
      "last_update_posted_date": "2018-11-23",
      "last_synced_at": "2026-05-22T09:05:15.499Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00412841"
    },
    {
      "nct_id": "NCT01473134",
      "title": "Safety and Efficacy of the Oxford Cementless Partial Knee System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis, Knee",
        "Avascular Necrosis of the Medial Femoral Condyle"
      ],
      "interventions": [
        {
          "name": "Oxford Cementless Partial Knee",
          "type": "DEVICE"
        },
        {
          "name": "Oxford Cemented Partial Knee",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 320,
      "start_date": "2011-12",
      "completion_date": "2021-11-30",
      "has_results": true,
      "last_update_posted_date": "2025-08-11",
      "last_synced_at": "2026-05-22T09:05:15.499Z",
      "location_count": 8,
      "location_summary": "Elkhart, Indiana • Indianapolis, Indiana • Council Bluffs, Iowa + 5 more",
      "locations": [
        {
          "city": "Elkhart",
          "state": "Indiana"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Council Bluffs",
          "state": "Iowa"
        },
        {
          "city": "Edina",
          "state": "Minnesota"
        },
        {
          "city": "Huntersville",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01473134"
    },
    {
      "nct_id": "NCT04145401",
      "title": "Post Market Clinical Follow-Up Study- EVOLUTION® Revision CCK",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Knee Osteoarthritis"
      ],
      "interventions": [
        {
          "name": "Revision Knee implants",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "MicroPort Orthopedics Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2020-09-30",
      "completion_date": "2033-11-01",
      "has_results": false,
      "last_update_posted_date": "2024-03-20",
      "last_synced_at": "2026-05-22T09:05:15.499Z",
      "location_count": 1,
      "location_summary": "Englewood, Colorado",
      "locations": [
        {
          "city": "Englewood",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04145401"
    },
    {
      "nct_id": "NCT00289107",
      "title": "Randomized Fixed Bearing vs Mobile Bearing Cruciate Substituting TKA",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis",
        "Rheumatoid Arthritis",
        "Other Inflammatory Arthritis",
        "Post-Traumatic Arthritis",
        "Juvenile Rheumatoid Arthritis",
        "Avascular Necrosis"
      ],
      "interventions": [
        {
          "name": "Total Knee Arthroplasty",
          "type": "DEVICE"
        },
        {
          "name": "Total knee replacement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DePuy Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 149,
      "start_date": "2001-04-01",
      "completion_date": "2007-11-01",
      "has_results": true,
      "last_update_posted_date": "2023-05-03",
      "last_synced_at": "2026-05-22T09:05:15.499Z",
      "location_count": 3,
      "location_summary": "Greensboro, North Carolina • Austin, Texas • Lakewood, Washington",
      "locations": [
        {
          "city": "Greensboro",
          "state": "North Carolina"
        },
        {
          "city": "Austin",
          "state": "Texas"
        },
        {
          "city": "Lakewood",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00289107"
    },
    {
      "nct_id": "NCT02036931",
      "title": "A Multicentre Observational Study to Evaluate Clinical Outcomes of the G7 Acetabular System",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Noninflammatory Degenerative Joint Disease",
        "Rheumatoid Arthritis"
      ],
      "interventions": [
        {
          "name": "Metal on Polyethylene articulation",
          "type": "DEVICE"
        },
        {
          "name": "Ceramic on Polyethylene articulation",
          "type": "DEVICE"
        },
        {
          "name": "Ceramic on Ceramic articulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 162,
      "start_date": "2013-03",
      "completion_date": "2025-05",
      "has_results": true,
      "last_update_posted_date": "2025-12-19",
      "last_synced_at": "2026-05-22T09:05:15.499Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02036931"
    },
    {
      "nct_id": "NCT02096211",
      "title": "Ceramic-on-Ceramic (COC) 36mm Acetabular Bearing Insert Post Approval Study-New Subjects (COC36mmPAS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Non-inflammatory Degenerative Joint Disease",
        "Osteoarthritis",
        "Avascular Necrosis",
        "Post-Traumatic Osteoarthritis of Hip"
      ],
      "interventions": [
        {
          "name": "COC 36mm",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DePuy Orthopaedics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 172,
      "start_date": "2014-06-01",
      "completion_date": "2023-12-31",
      "has_results": true,
      "last_update_posted_date": "2025-07-16",
      "last_synced_at": "2026-05-22T09:05:15.499Z",
      "location_count": 9,
      "location_summary": "Sacramento, California • Denver, Colorado • Tampa, Florida + 5 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02096211"
    },
    {
      "nct_id": "NCT05283148",
      "title": "Sickle Cell Disease (SCD) Bone Pain Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sickle Cell Disease",
        "Sickle Cell Anemia",
        "Low Bone Density",
        "Osteoporosis",
        "Osteopenia",
        "Vertebral Fracture",
        "Vertebral Compression",
        "Osteonecrosis",
        "Ischemic Necrosis",
        "Avascular Necrosis"
      ],
      "interventions": [
        {
          "name": "Dual-energy X-ray absorptiometry",
          "type": "OTHER"
        },
        {
          "name": "Vertebral fracture analysis",
          "type": "OTHER"
        },
        {
          "name": "Adult Sickle Cell Quality of Life Measurement System pain impact questionnaire",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 53,
      "start_date": "2022-11-03",
      "completion_date": "2026-07-31",
      "has_results": true,
      "last_update_posted_date": "2025-08-24",
      "last_synced_at": "2026-05-22T09:05:15.499Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05283148"
    },
    {
      "nct_id": "NCT00765362",
      "title": "Mobile - Bearing Knee Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Inflammatory Tissue Disorder",
        "Osteoarthritis",
        "Avascular Necrosis",
        "Post-traumatic Arthritis",
        "Secondary Arthritis"
      ],
      "interventions": [
        {
          "name": "Encore Mobile-Bearing Knee",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Encore Medical, L.P.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 419,
      "start_date": "2000-01",
      "completion_date": "2008-08",
      "has_results": true,
      "last_update_posted_date": "2011-05-11",
      "last_synced_at": "2026-05-22T09:05:15.499Z",
      "location_count": 8,
      "location_summary": "Phoenix, Arizona • Fountain Valley, California • Miami, Florida + 5 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Fountain Valley",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Garden City",
          "state": "Michigan"
        },
        {
          "city": "Hilton Head Island",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00765362"
    },
    {
      "nct_id": "NCT00699088",
      "title": "A Clinical Investigation of the Balance® Microplasty™ Hip System",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteoarthritis, Hip",
        "Rheumatoid Arthritis",
        "Avascular Necrosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Biomet Orthopedics, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2005-01",
      "completion_date": "2013-03",
      "has_results": false,
      "last_update_posted_date": "2017-06-21",
      "last_synced_at": "2026-05-22T09:05:15.499Z",
      "location_count": 4,
      "location_summary": "Chicago, Illinois • Pittsburgh, Pennsylvania • Fredericksburg, Virginia + 1 more",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Fredericksburg",
          "state": "Virginia"
        },
        {
          "city": "Monroe",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00699088"
    }
  ]
}