{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Best+Vitelliform+Macular+Dystrophy",
    "query": {
      "condition": "Best Vitelliform Macular Dystrophy"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T16:26:22.016Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06491615",
      "title": "National Ophthalmic Genotyping and Phenotyping Network (eyeGENE (Registered Trademark)), Stage 3 - Expansion of DNA and Data Repositories for Rare Inherited Ophthalmic Diseases",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Inherited Ophthalmic Diseases",
        "Hypopigmentation Disorder",
        "Corneal Dystrophy",
        "Blue-cone Monochromacy",
        "Best Disease",
        "Aniridia",
        "Albinism"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Eye Institute (NEI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "120 Years",
        "sex": "ALL",
        "summary": "1 Day to 120 Years"
      },
      "enrollment_count": 1000,
      "start_date": "2024-07-12",
      "completion_date": "2054-06-27",
      "has_results": false,
      "last_update_posted_date": "2026-06-09",
      "last_synced_at": "2026-07-22T16:26:22.016Z",
      "location_count": 2,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06491615"
    },
    {
      "nct_id": "NCT02162953",
      "title": "Stem Cell Models of Best Disease and Other Retinal Degenerative Diseases.",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Retinal Disease",
        "Bestrophinopathy",
        "Best Vitelliform Macular Dystrophy",
        "Adult Onset Vitelliform Macular Dystrophy",
        "Autosomal Dominant Vitreoretinalchoroidopathy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "5 Years and older"
      },
      "enrollment_count": 48,
      "start_date": "2014-02",
      "completion_date": "2022-12-31",
      "has_results": false,
      "last_update_posted_date": "2023-01-09",
      "last_synced_at": "2026-07-22T16:26:22.016Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02162953"
    },
    {
      "nct_id": "NCT07185256",
      "title": "Safety and Tolerability of Subretinally Injected OPGx-BEST1 in Patients With Best Vitelliform Macular Dystrophy (BVMD) or Autosomal-Recessive Bestrophinopathy (ARB)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "ARB",
        "BVMD",
        "Autosomal-Dominant Bestrophinopathy",
        "Best Vitelliform Macular Dystrophy"
      ],
      "interventions": [
        {
          "name": "OPGx-BEST1",
          "type": "GENETIC"
        }
      ],
      "intervention_types": [
        "GENETIC"
      ],
      "sponsor": "Opus Genetics, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2025-09-25",
      "completion_date": "2030-08",
      "has_results": false,
      "last_update_posted_date": "2026-03-24",
      "last_synced_at": "2026-07-22T16:26:22.016Z",
      "location_count": 4,
      "location_summary": "Los Angeles, California • Gainesville, Florida • Cincinnati, Ohio + 1 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07185256"
    },
    {
      "nct_id": "NCT01432847",
      "title": "Cell Collection to Study Eye Diseases",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Retinal Disease",
        "AMD",
        "Retinal Degeneration",
        "Retinitis Pigmentosa"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Eye Institute (NEI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "120 Years",
        "sex": "ALL",
        "summary": "1 Day to 120 Years"
      },
      "enrollment_count": 930,
      "start_date": "2011-09-07",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2026-06-22",
      "last_synced_at": "2026-07-22T16:26:22.016Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01432847"
    },
    {
      "nct_id": "NCT02435940",
      "title": "Inherited Retinal Degenerative Disease Registry",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Eye Diseases Hereditary",
        "Retinal Disease",
        "Achromatopsia",
        "Bardet-Biedl Syndrome",
        "Bassen-Kornzweig Syndrome",
        "Batten Disease",
        "Best Disease",
        "Choroidal Dystrophy",
        "Choroideremia",
        "Cone Dystrophy",
        "Cone-Rod Dystrophy",
        "Congenital Stationary Night Blindness",
        "Enhanced S-Cone Syndrome",
        "Fundus Albipunctatus",
        "Goldmann-Favre Syndrome",
        "Gyrate Atrophy",
        "Juvenile Macular Degeneration",
        "Kearns-Sayre Syndrome",
        "Leber Congenital Amaurosis",
        "Refsum Syndrome",
        "Retinitis Pigmentosa",
        "Retinitis Punctata Albescens",
        "Retinoschisis",
        "Rod-Cone Dystrophy",
        "Rod Dystrophy",
        "Rod Monochromacy",
        "Stargardt Disease",
        "Usher Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Foundation Fighting Blindness",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 20000,
      "start_date": "2014-06",
      "completion_date": "2037-06",
      "has_results": false,
      "last_update_posted_date": "2026-05-19",
      "last_synced_at": "2026-07-22T16:26:22.016Z",
      "location_count": 1,
      "location_summary": "Columbia, Maryland",
      "locations": [
        {
          "city": "Columbia",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02435940"
    },
    {
      "nct_id": "NCT00470977",
      "title": "Treatment of Exudative and Vasogenic Chorioretinal Diseases Including Variants of AMD and Other CNV Related Maculopathy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Coats' Disease",
        "Idiopathic Retinal Telangiectasia",
        "Retinal Angiomatous Proliferation",
        "Polypoidal Choroidal Vasculopathy",
        "Pseudoxanthoma Elasticum",
        "Pathological Myopia",
        "Multi-focal Choroiditis",
        "Rubeosis Iridis",
        "Von Hippel Lindau Disease",
        "BEST VITELLIFORM MACULAR DYSTROPHY, MULTIFOCAL (Disorder)"
      ],
      "interventions": [
        {
          "name": "ranibizumab injection (0.5 mg)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Manhattan Eye, Ear & Throat Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2007-05",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2012-10-25",
      "last_synced_at": "2026-07-22T16:26:22.016Z",
      "location_count": 2,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00470977"
    },
    {
      "nct_id": "NCT04356716",
      "title": "Sildenafil for Treatment of Choroidal Ischemia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Choroidal Ischemia",
        "Vitelliform Macular Dystrophy",
        "Age-related Macular Degeneration",
        "Central Serous Retinopathy",
        "Retinitis Pigmentosa"
      ],
      "interventions": [
        {
          "name": "Sildenafil",
          "type": "DRUG"
        },
        {
          "name": "Standard of Care Sildenafil",
          "type": "OTHER"
        },
        {
          "name": "Ocular Coherence Tomography-Angiography (OCT-A)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Visual Acuity (VA)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2014-11-11",
      "completion_date": "2020-02-18",
      "has_results": true,
      "last_update_posted_date": "2025-07-04",
      "last_synced_at": "2026-07-22T16:26:22.016Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04356716"
    },
    {
      "nct_id": "NCT05809635",
      "title": "Study of BEST1 Vitelliform Macular Dystrophy",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Best Vitelliform Macular Dystrophy",
        "Retinitis Pigmentosa"
      ],
      "interventions": [
        {
          "name": "Natural History Study",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 52,
      "start_date": "2021-03-30",
      "completion_date": "2026-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-30",
      "last_synced_at": "2026-07-22T16:26:22.016Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05809635"
    }
  ]
}