{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Bicuspid&page=2",
    "query": {
      "condition": "Bicuspid",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Bicuspid&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T02:43:03.924Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04946201",
      "title": "Premolar Extractions for Obstructive Sleep Apnea in Children With Overjet",
      "overall_status": "SUSPENDED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Obstructive Sleep Apnea",
        "Malocclusion"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Mohamed Bazina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "15 Years",
        "sex": "ALL",
        "summary": "10 Years to 15 Years"
      },
      "enrollment_count": 60,
      "start_date": "2021-09-02",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-12-24",
      "last_synced_at": "2026-06-11T02:43:03.924Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04946201"
    },
    {
      "nct_id": "NCT03570333",
      "title": "Progenitor Potential of Mesenchymal Stem Cells in Palatal Tissue Harvested From Molar and Premolar Sites",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingival Recession",
        "Lack of Keratinized Gingiva (Disorder)"
      ],
      "interventions": [
        {
          "name": "progenitor potential of Gingival Mesenchymal cells",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 7,
      "start_date": "2018-09-17",
      "completion_date": "2025-12-06",
      "has_results": false,
      "last_update_posted_date": "2025-12-19",
      "last_synced_at": "2026-06-11T02:43:03.924Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03570333"
    },
    {
      "nct_id": "NCT01920815",
      "title": "Bicuspid Valve Aortopathy Feasibility Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bicuspid Aortic Valve"
      ],
      "interventions": [
        {
          "name": "No interventions",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 500,
      "start_date": "2013-07",
      "completion_date": "2017-10-04",
      "has_results": false,
      "last_update_posted_date": "2018-09-19",
      "last_synced_at": "2026-06-11T02:43:03.924Z",
      "location_count": 6,
      "location_summary": "Los Angeles, California • Denver, Colorado • Atlanta, Georgia + 3 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01920815"
    },
    {
      "nct_id": "NCT01322165",
      "title": "National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Marfan Syndrome",
        "Turner Syndrome",
        "Ehlers-Danlos Syndrome",
        "Loeys-Dietz Syndrome",
        "FBN1, TGFBR1, TGFBR2, ACTA2 or MYH11 Genetic Mutation",
        "Bicuspid Aortic Valve Without Known Family History",
        "Bicuspid Aortic Valve With Family History",
        "Bicuspid Aortic Valve With Coarctation",
        "Familial Thoracic Aortic Aneurysm and Dissections",
        "Shprintzen-Goldberg Syndrome",
        "Other Aneur/Diss of Thoracic Aorta Not Due to Trauma, <50yo",
        "Other Congenital Heart Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 3706,
      "start_date": "2007-11",
      "completion_date": "2016-09",
      "has_results": false,
      "last_update_posted_date": "2016-12-20",
      "last_synced_at": "2026-06-11T02:43:03.924Z",
      "location_count": 7,
      "location_summary": "Honolulu, Hawaii • Baltimore, Maryland • New York, New York + 3 more",
      "locations": [
        {
          "city": "Honolulu",
          "state": "Hawaii"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01322165"
    },
    {
      "nct_id": "NCT01194362",
      "title": "A Study to Identify Differences in Gene Expression in Patients With Bicuspid and Tricuspid Valve Disease",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Aortic Valve Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Baylor Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 91,
      "start_date": "2010-06-20",
      "completion_date": "2022-09-23",
      "has_results": false,
      "last_update_posted_date": "2026-01-26",
      "last_synced_at": "2026-06-11T02:43:03.924Z",
      "location_count": 1,
      "location_summary": "Plano, Texas",
      "locations": [
        {
          "city": "Plano",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01194362"
    },
    {
      "nct_id": "NCT04149600",
      "title": "Identification of Genetic Causes of Calcific Aortic Valve Disease",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Calcific Aortic Stenosis",
        "Calcific Aortic Stenosis - Bicuspid Valve",
        "Aortic Valve Disease",
        "Aortic Valve Calcification",
        "Aortic Diseases",
        "Aortic Aneurysm",
        "Aortic Valve Cusp Abnormality",
        "Aortic Valve Disease Mixed",
        "Aortic Valve Insufficiency"
      ],
      "interventions": [
        {
          "name": "Patients scheduled to undergo aortic valve replacement or aortic surgery at BIDMC will be approached for participation in this study.",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "20 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2018-09-25",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-05-30",
      "last_synced_at": "2026-06-11T02:43:03.924Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04149600"
    },
    {
      "nct_id": "NCT01390181",
      "title": "The Effect of Losartan in Bicuspid Aortic Valve Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bicuspid Aortic Valve",
        "Thoracic Aortic Aneurysm"
      ],
      "interventions": [
        {
          "name": "Cozaar",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 4,
      "start_date": "2011-09",
      "completion_date": "2014-01",
      "has_results": true,
      "last_update_posted_date": "2017-04-14",
      "last_synced_at": "2026-06-11T02:43:03.924Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01390181"
    },
    {
      "nct_id": "NCT01369134",
      "title": "Clinical Evaluation of a Self-etch Adhesive Using a Selective Etch Technique",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Adper Easy Bond Self-etch dental adhesive",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Solventum US LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2011-01",
      "completion_date": "2013-02",
      "has_results": false,
      "last_update_posted_date": "2024-10-02",
      "last_synced_at": "2026-06-11T02:43:03.924Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01369134"
    },
    {
      "nct_id": "NCT03836521",
      "title": "Bicuspid Aortic Valve Stenosis Transcatheter Aortic Valve Replacement Registry",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bicuspid Aortic Valve"
      ],
      "interventions": [
        {
          "name": "Transcatheter aortic valve replacement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "129 Years",
        "sex": "ALL",
        "summary": "19 Years to 129 Years"
      },
      "enrollment_count": 2000,
      "start_date": "2016-08-15",
      "completion_date": "2028-08-15",
      "has_results": false,
      "last_update_posted_date": "2019-02-11",
      "last_synced_at": "2026-06-11T02:43:03.924Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03836521"
    },
    {
      "nct_id": "NCT01959503",
      "title": "Progel Vascular Sealant",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Valve Stenosis",
        "Aneurysm of Ascending Aorta",
        "Aortic Valve Disorder",
        "Bicuspid Valve Disorder"
      ],
      "interventions": [
        {
          "name": "Progel Vascular Sealant",
          "type": "DEVICE"
        },
        {
          "name": "Gelfoam Plus",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "C. R. Bard",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 158,
      "start_date": "2013-11",
      "completion_date": "2014-12",
      "has_results": true,
      "last_update_posted_date": "2017-04-10",
      "last_synced_at": "2026-06-11T02:43:03.924Z",
      "location_count": 19,
      "location_summary": "Los Angeles, California • Aurora, Colorado • Gainesville, Florida + 16 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Pocatello",
          "state": "Idaho"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01959503"
    }
  ]
}