{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Biofilms",
    "query": {
      "condition": "Biofilms"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 60,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Biofilms&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T18:04:00.831Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07408245",
      "title": "Effects of Biocidin on Oral Biofilms",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Biofilm"
      ],
      "interventions": [
        {
          "name": "Biocidin Liquid",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "OvationLab",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "25 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2026-02-17",
      "completion_date": "2026-04",
      "has_results": false,
      "last_update_posted_date": "2026-03-11",
      "last_synced_at": "2026-07-22T18:04:00.831Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07408245"
    },
    {
      "nct_id": "NCT02178046",
      "title": "Non-Invasive Oral Biofilm Characterization",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "optical measurements",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "18 Years to 25 Years"
      },
      "enrollment_count": 0,
      "start_date": "2014-05-23",
      "completion_date": "2019-08-12",
      "has_results": false,
      "last_update_posted_date": "2022-11-01",
      "last_synced_at": "2026-07-22T18:04:00.831Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02178046"
    },
    {
      "nct_id": "NCT05607030",
      "title": "A Second Trial of the Abbreviated Protocol Two-Stage Exchange",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Prosthetic-joint Infection"
      ],
      "interventions": [
        {
          "name": "VT-X7 Treatment System",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Two-stage exchange arthroplasty",
          "type": "PROCEDURE"
        },
        {
          "name": "SOC Antibiotics",
          "type": "DRUG"
        },
        {
          "name": "Experimental Antibiotics",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Osteal Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "22 Years to 84 Years"
      },
      "enrollment_count": 76,
      "start_date": "2023-01-23",
      "completion_date": "2024-10-30",
      "has_results": false,
      "last_update_posted_date": "2025-01-07",
      "last_synced_at": "2026-07-22T18:04:00.831Z",
      "location_count": 19,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • Sarasota, Florida + 15 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        },
        {
          "city": "Weston",
          "state": "Florida"
        },
        {
          "city": "Saginaw",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05607030"
    },
    {
      "nct_id": "NCT03070925",
      "title": "Prospective PuraPly™ AM Case Series Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pressure Ulcers",
        "Venous Ulcers",
        "Diabetic Ulcers",
        "Surgical Wounds",
        "Trauma Wounds"
      ],
      "interventions": [
        {
          "name": "PuraPly™ Antimicrobial Wound Matrix",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Organogenesis",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 43,
      "start_date": "2016-11",
      "completion_date": "2017-05",
      "has_results": false,
      "last_update_posted_date": "2017-08-31",
      "last_synced_at": "2026-07-22T18:04:00.831Z",
      "location_count": 1,
      "location_summary": "Lake Success, New York",
      "locations": [
        {
          "city": "Lake Success",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03070925"
    },
    {
      "nct_id": "NCT03513497",
      "title": "IFI16 is a Periodontitis Modulating Protein",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Severe Periodontitis",
        "Acute Inflammatory Response"
      ],
      "interventions": [
        {
          "name": "Customized acrylic mouthguard",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 69,
      "start_date": "2018-10-18",
      "completion_date": "2023-06-28",
      "has_results": true,
      "last_update_posted_date": "2024-07-03",
      "last_synced_at": "2026-07-22T18:04:00.831Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03513497"
    },
    {
      "nct_id": "NCT01712672",
      "title": "Bacterial Arrangement on the Teeth",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dental Plaque",
        "Oral Health",
        "Periodontal Disease and Caries",
        "Periodontal Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Dental and Craniofacial Research (NIDCR)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2013-01-16",
      "completion_date": "2016-01-07",
      "has_results": false,
      "last_update_posted_date": "2025-07-30",
      "last_synced_at": "2026-07-22T18:04:00.831Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01712672"
    },
    {
      "nct_id": "NCT03461783",
      "title": "Activated Carbon Interphase Effect on Biofilm and Total Bacterial Load",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wound Infection"
      ],
      "interventions": [
        {
          "name": "Zorflex Activated Carbon Dressing",
          "type": "DEVICE"
        },
        {
          "name": "Standard of Care",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Brock Liden, DPM",
      "sponsor_class": "INDIV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2017-06-26",
      "completion_date": "2019-02-01",
      "has_results": false,
      "last_update_posted_date": "2019-02-27",
      "last_synced_at": "2026-07-22T18:04:00.831Z",
      "location_count": 2,
      "location_summary": "Circleville, Ohio • Logan, Ohio",
      "locations": [
        {
          "city": "Circleville",
          "state": "Ohio"
        },
        {
          "city": "Logan",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03461783"
    },
    {
      "nct_id": "NCT04662632",
      "title": "Abbreviated Protocol for Two-Stage Exchange",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Prosthetic Joint Infection"
      ],
      "interventions": [
        {
          "name": "VT-X7 Treatment System with Tobramycin Sulfate",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Standard of Care",
          "type": "DRUG"
        },
        {
          "name": "Two-stage exchange arthroplasty",
          "type": "PROCEDURE"
        },
        {
          "name": "VT-X7 Treatment System with Vancomycin Hydrochloride",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Osteal Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "22 Years to 84 Years"
      },
      "enrollment_count": 76,
      "start_date": "2021-11-01",
      "completion_date": "2023-12-22",
      "has_results": true,
      "last_update_posted_date": "2026-04-21",
      "last_synced_at": "2026-07-22T18:04:00.831Z",
      "location_count": 17,
      "location_summary": "Phoenix, Arizona • Torrance, California • Washington D.C., District of Columbia + 13 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Weston",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04662632"
    },
    {
      "nct_id": "NCT00098267",
      "title": "Collection of Dental Plaque and Saliva for Studies of Bacterial Colonization of Teeth",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Healthy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Dental and Craniofacial Research (NIDCR)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "3 Months and older"
      },
      "enrollment_count": 30,
      "start_date": "2004-12-02",
      "completion_date": "2009-08-03",
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-07-22T18:04:00.831Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00098267"
    },
    {
      "nct_id": "NCT00663637",
      "title": "Removal of Endotracheal Tube Secretions Comprehensively Until Extubation",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Mechanical Ventilation",
        "Pneumonia"
      ],
      "interventions": [
        {
          "name": "CAM (Complete Airway Management) Catheters",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "O. M. Neotech, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 30,
      "start_date": "2008-04",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2008-05-29",
      "last_synced_at": "2026-07-22T18:04:00.831Z",
      "location_count": 1,
      "location_summary": "Cape Girardeau, Missouri",
      "locations": [
        {
          "city": "Cape Girardeau",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00663637"
    }
  ]
}