{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Bipolar+1+Depression",
    "query": {
      "condition": "Bipolar 1 Depression"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 13,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Bipolar+1+Depression&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T22:15:22.322Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06740383",
      "title": "Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Schizophrenia Spectrum and Other Psychotic Disorders",
        "Schizophrenia",
        "Delusional Disorder",
        "Bipolar 1 Disorder",
        "Schizoaffective Disorder",
        "Psychosis Not Otherwise Specified",
        "Early Psychosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 320,
      "start_date": "2023-01-01",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-10",
      "last_synced_at": "2026-06-10T22:15:22.322Z",
      "location_count": 6,
      "location_summary": "Hartford, Connecticut • Athens, Georgia • Chicago, Illinois + 3 more",
      "locations": [
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Athens",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Belmont",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06740383"
    },
    {
      "nct_id": "NCT05227209",
      "title": "A Clinical Trial to Determine the Long-term Safety and Tolerability of an Investigational Drug in People With Major Depressive Episode Associated With Bipolar I Disorder (Bipolar I Depression).",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Depressive Episodes, Bipolar I Depression"
      ],
      "interventions": [
        {
          "name": "SEP-4199 CR",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sumitomo Pharma America, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 64,
      "start_date": "2022-03-17",
      "completion_date": "2023-11-17",
      "has_results": true,
      "last_update_posted_date": "2025-02-21",
      "last_synced_at": "2026-06-10T22:15:22.322Z",
      "location_count": 25,
      "location_summary": "Huntsville, Alabama • Anaheim, California • Imperial, California + 22 more",
      "locations": [
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Imperial",
          "state": "California"
        },
        {
          "city": "Riverside",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05227209"
    },
    {
      "nct_id": "NCT05956483",
      "title": "Study to Assess Accuracy of Rapid Mood Screener in Adult Participants With Unipolar Major Depressive Disorder or Bipolar 1 Disorder in Real World Setting",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bipolar I Disorder"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "AbbVie",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 423,
      "start_date": "2023-12-04",
      "completion_date": "2024-08-16",
      "has_results": false,
      "last_update_posted_date": "2024-08-20",
      "last_synced_at": "2026-06-10T22:15:22.322Z",
      "location_count": 9,
      "location_summary": "Costa Mesa, California • Cromwell, Connecticut • Doral, Florida + 5 more",
      "locations": [
        {
          "city": "Costa Mesa",
          "state": "California"
        },
        {
          "city": "Cromwell",
          "state": "Connecticut"
        },
        {
          "city": "Doral",
          "state": "Florida"
        },
        {
          "city": "Doral",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05956483"
    },
    {
      "nct_id": "NCT00938301",
      "title": "A First In Human Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of PF-04455242 In Single Rising Doses In Healthy Adult Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Bipolar Depression"
      ],
      "interventions": [
        {
          "name": "PF-04455242",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 18,
      "start_date": "2009-04",
      "completion_date": "2009-07",
      "has_results": false,
      "last_update_posted_date": "2009-10-16",
      "last_synced_at": "2026-06-10T22:15:22.322Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00938301"
    },
    {
      "nct_id": "NCT00080314",
      "title": "Study of Aripiprazole in Patients With Bipolar I Disorder With a Major Depression Episode",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Bipolar Disorder"
      ],
      "interventions": [
        {
          "name": "Aripiprazole",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Otsuka Pharmaceutical Development & Commercialization, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 400,
      "start_date": "2004-01",
      "completion_date": "2006-10",
      "has_results": false,
      "last_update_posted_date": "2013-11-11",
      "last_synced_at": "2026-06-10T22:15:22.322Z",
      "location_count": 28,
      "location_summary": "Tuscaloosa, Alabama • Little Rock, Arkansas • San Diego, California + 25 more",
      "locations": [
        {
          "city": "Tuscaloosa",
          "state": "Alabama"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Sherman Oaks",
          "state": "California"
        },
        {
          "city": "Norwich",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00080314"
    },
    {
      "nct_id": "NCT05705063",
      "title": "Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar Illness",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bipolar Disorder I",
        "Bipolar II Disorder",
        "Bipolar I Disorder",
        "Bipolar Disorder",
        "Bipolar Depression",
        "Bipolar and Related Disorders",
        "Bipolar Disorder, Type 1",
        "Bipolar Disorder, Type 2",
        "Bipolar Disorder, Mixed",
        "Obesity",
        "Metabolic Syndrome",
        "Ketogenic Dieting",
        "Weight Gain",
        "Brain Metabolic Disorder",
        "Psychotropic Agents Causing Adverse Effects in Therapeutic Use"
      ],
      "interventions": [
        {
          "name": "LCHF Ketogenic Diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 30,
      "start_date": "2023-01-30",
      "completion_date": "2024-12-30",
      "has_results": false,
      "last_update_posted_date": "2023-01-30",
      "last_synced_at": "2026-06-10T22:15:22.322Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05705063"
    },
    {
      "nct_id": "NCT00939887",
      "title": "A Study Of Kappa Opioid Receptor Occupancy Of PF-04455242, Using PET (Positron Emission Tomography)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Bipolar Disorder",
        "Depression"
      ],
      "interventions": [
        {
          "name": "PF-04455242",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 12,
      "start_date": "2009-09",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2010-02-08",
      "last_synced_at": "2026-06-10T22:15:22.322Z",
      "location_count": 3,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00939887"
    },
    {
      "nct_id": "NCT05169710",
      "title": "A Clinical Study of an Investigational Drug for the Treatment of Major Depressive Episode Associated With Bipolar I Disorder.",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Depressive Episodes, Bipolar I Depression"
      ],
      "interventions": [
        {
          "name": "SEP-4199 CR 200 mg",
          "type": "DRUG"
        },
        {
          "name": "SEP-4199 CR 400 mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sumitomo Pharma America, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 83,
      "start_date": "2021-12-21",
      "completion_date": "2023-10-18",
      "has_results": true,
      "last_update_posted_date": "2024-10-03",
      "last_synced_at": "2026-06-10T22:15:22.322Z",
      "location_count": 34,
      "location_summary": "Huntsville, Alabama • Bryant, Arkansas • Anaheim, California + 30 more",
      "locations": [
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Bryant",
          "state": "Arkansas"
        },
        {
          "city": "Anaheim",
          "state": "California"
        },
        {
          "city": "Imperial",
          "state": "California"
        },
        {
          "city": "Riverside",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05169710"
    },
    {
      "nct_id": "NCT02722967",
      "title": "Exploratory Trial to Assess the Functionality of an Integrated Call Center for the Digital Medicine System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Schizophrenia",
        "Major Depressive Disorder",
        "Bipolar I Disorder"
      ],
      "interventions": [
        {
          "name": "Aripiprazole + IEM (Ingestible Event Marker)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Otsuka Pharmaceutical Development & Commercialization, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 49,
      "start_date": "2016-03",
      "completion_date": "2016-09",
      "has_results": true,
      "last_update_posted_date": "2018-05-23",
      "last_synced_at": "2026-06-10T22:15:22.322Z",
      "location_count": 4,
      "location_summary": "Granada Hills, California • Rochester, New York • Durham, North Carolina + 1 more",
      "locations": [
        {
          "city": "Granada Hills",
          "state": "California"
        },
        {
          "city": "Rochester",
          "state": "New York"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02722967"
    },
    {
      "nct_id": "NCT04031469",
      "title": "A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease",
      "overall_status": "SUSPENDED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Gut Microbiome",
        "Gastrointestinal Microbiome",
        "Autism",
        "Autism Spectrum Disorder",
        "Autism Spectrum Disorder High-Functioning",
        "Alzheimer Disease",
        "Alzheimer Dementia (AD)",
        "Alzheimer Dementia",
        "Alzheimer Disease (AD)",
        "Crohn",
        "Crohn Colitis",
        "Crohn Disease (CD)",
        "Crohn Disease Colon",
        "Myalgic Encephalomyelitis",
        "ME/CFS",
        "Myalgic Encephalomyelitis (ME)",
        "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome",
        "Psoriasis",
        "Psoriasis Annularis",
        "Psoriasis Chronic",
        "Chronic Urinary Tract Infection",
        "Ulcerative Colitis (Disorder)",
        "Ulcerative Colitis (UC)",
        "Ulcerative Colitis Acute",
        "Ulcerative Colitis Chronic",
        "Multiple Sclerosis",
        "Multiple Sclerosis (MS) - Relapsing-remitting",
        "Multiple Sclerosis (MS) Primary Progressive",
        "Constipation Chronic Idiopathic",
        "Constipation",
        "Celiac",
        "Celiac Disease",
        "Celiac Sprue",
        "Lyme Arthritis",
        "Lyme Borreliosis, Nervous System",
        "Lyme Disease, Chronic",
        "Cholesterol",
        "Cholesterol Level, High",
        "Cancer",
        "Colon Cancer",
        "Amyotrophic Lateral Sclerosis (ALS)",
        "Amyotrophic Lateral Sclerosis",
        "Rheumatoid Arthritis (RA)",
        "Rheumatoid Arthritis - Rheumatism",
        "Chronic Fatigue Syndrome (CFS)",
        "PARKINSON DISEASE (Disorder)",
        "Parkinson Disease",
        "Parkinson Disease (PD)",
        "Depression",
        "Major Depressive Disorder (MDD)",
        "Depression Disorder",
        "Depression in Adults",
        "Anxiety",
        "Anxiety Disorder Generalized",
        "Obsessive Compulsive Disorder (OCD)",
        "Obsessive Compulsive Disorder OCD",
        "Obsessive - Compulsive Disorder",
        "Bipolar",
        "Bipolar 1 Disorder",
        "Bipolar Disorder (BD)",
        "Bipolar Disorder I and II",
        "Bipolar and Related Disorders",
        "Migraine",
        "Migraine Disorder",
        "Diabetes (DM)",
        "Diabetes",
        "Lupus",
        "Lupus Erythematosus",
        "Epidermolysis Bullosa (EB)",
        "Mesothelioma",
        "Mesothelioma Malignant",
        "IBS (Irritable Bowel Syndrome)",
        "Irritable Bowel",
        "IBS - Irritable Bowel Syndrome",
        "Irritable Bowel Syndrome (IBS)",
        "Eczema",
        "Eczema Atopic Dermatitis",
        "Acne",
        "Myasthaenia Gravis",
        "Gout"
      ],
      "interventions": [
        {
          "name": "There is no intervention in this study",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "ProgenaBiome",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2019-07-11",
      "completion_date": "2030-12-10",
      "has_results": false,
      "last_update_posted_date": "2025-07-31",
      "last_synced_at": "2026-06-10T22:15:22.322Z",
      "location_count": 1,
      "location_summary": "Ventura, California",
      "locations": [
        {
          "city": "Ventura",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04031469"
    }
  ]
}