{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Bipolar+Disorder%2C+Type+1", "query": { "condition": "Bipolar Disorder, Type 1" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 12, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Bipolar+Disorder%2C+Type+1&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-05-22T03:07:12.806Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06951711", "title": "A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar Disorder Type I With Mania or Mania With Mixed Features" ], "interventions": [ { "name": "KarXT", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 274, "start_date": "2025-06-13", "completion_date": "2026-11-02", "has_results": false, "last_update_posted_date": "2026-04-29", "last_synced_at": "2026-05-22T03:07:12.806Z", "location_count": 27, "location_summary": "Little Rock, Arkansas • Rogers, Arkansas • Culver City, California + 23 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Rogers", "state": "Arkansas" }, { "city": "Culver City", "state": "California" }, { "city": "Riverside", "state": "California" }, { "city": "Torrance", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06951711" }, { "nct_id": "NCT00321516", "title": "Drug-drug Interaction Study of Aripiprazole and Lamotrigine in Patients With Bipolar Type I Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "aripiprazole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Otsuka Pharmaceutical Development & Commercialization, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 20, "start_date": "2006-07", "completion_date": "2007-02", "has_results": false, "last_update_posted_date": "2013-11-08", "last_synced_at": "2026-05-22T03:07:12.806Z", "location_count": 4, "location_summary": "Philadelphia, Pennsylvania • Austin, Texas • Bellaire, Texas + 1 more", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" }, { "city": "Austin", "state": "Texas" }, { "city": "Bellaire", "state": "Texas" }, { "city": "Desota", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00321516" }, { "nct_id": "NCT00852592", "title": "Light Therapy for Bipolar Disorder. Efficacy of Light Therapy for Bipolar Depression: A Randomized Controlled Trial", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar Disorder", "Major Depressive Episode" ], "interventions": [ { "name": "7000lux broad-spectrum light", "type": "DEVICE" }, { "name": "50lux dim red light", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Northwestern University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 46, "start_date": "2009-05", "completion_date": "2015-02", "has_results": true, "last_update_posted_date": "2016-11-07", "last_synced_at": "2026-05-22T03:07:12.806Z", "location_count": 2, "location_summary": "Pittsburgh, Pennsylvania", "locations": [ { "city": "Pittsburgh", "state": "Pennsylvania" }, { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00852592" }, { "nct_id": "NCT00067262", "title": "An Outpatient Study of the Effectiveness and Safety of Depakote ER in the Treatment of Mania/Bipolar Disorder in Children and Adolescents", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "Divalproex Sodium Extended-Release Tablets", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Abbott", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "10 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "10 Years to 17 Years" }, "enrollment_count": 150, "start_date": "2003-03", "completion_date": null, "has_results": false, "last_update_posted_date": "2006-08-04", "last_synced_at": "2026-05-22T03:07:12.806Z", "location_count": 16, "location_summary": "Stanford, California • Washington D.C., District of Columbia • Altamonte Springs, Florida + 13 more", "locations": [ { "city": "Stanford", "state": "California" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Altamonte Springs", "state": "Florida" }, { "city": "Miami", "state": "Florida" }, { "city": "North Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00067262" }, { "nct_id": "NCT06373016", "title": "Use of Ketosis in Modulating Metabolic Pathways in Bipolar Disorder", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Bipolar Disorder", "Bipolar Disorder Type 1" ], "interventions": [ { "name": "Glucose", "type": "DIETARY_SUPPLEMENT" }, { "name": "Ketones", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "Stony Brook University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "45 Years", "sex": "ALL", "summary": "18 Years to 45 Years" }, "enrollment_count": 100, "start_date": "2024-01-26", "completion_date": "2027-02-01", "has_results": false, "last_update_posted_date": "2026-04-15", "last_synced_at": "2026-05-22T03:07:12.806Z", "location_count": 3, "location_summary": "Belmont, Massachusetts • Charlestown, Massachusetts • Stony Brook, New York", "locations": [ { "city": "Belmont", "state": "Massachusetts" }, { "city": "Charlestown", "state": "Massachusetts" }, { "city": "Stony Brook", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT06373016" }, { "nct_id": "NCT06929273", "title": "A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar Disorder Type I With Mania" ], "interventions": [ { "name": "KarXT", "type": "DRUG" }, { "name": "Lithium", "type": "DRUG" }, { "name": "Valproate", "type": "DRUG" }, { "name": "Lamotrigine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 450, "start_date": "2025-07-18", "completion_date": "2028-06-13", "has_results": false, "last_update_posted_date": "2026-05-12", "last_synced_at": "2026-05-22T03:07:12.806Z", "location_count": 52, "location_summary": "Glendale, Arizona • Bentonville, Arkansas • Little Rock, Arkansas + 41 more", "locations": [ { "city": "Glendale", "state": "Arizona" }, { "city": "Bentonville", "state": "Arkansas" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Rogers", "state": "Arkansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06929273" }, { "nct_id": "NCT06419582", "title": "BHV-7000 Acute Treatment of Bipolar Mania", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "BHV-7000", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Biohaven Therapeutics Ltd.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 274, "start_date": "2024-05-28", "completion_date": "2025-01-30", "has_results": false, "last_update_posted_date": "2025-12-16", "last_synced_at": "2026-05-22T03:07:12.806Z", "location_count": 32, "location_summary": "Bentonville, Arkansas • Little Rock, Arkansas • Rogers, Arkansas + 26 more", "locations": [ { "city": "Bentonville", "state": "Arkansas" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Rogers", "state": "Arkansas" }, { "city": "Anaheim", "state": "California" }, { "city": "Bellflower", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06419582" }, { "nct_id": "NCT04211428", "title": "A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Bipolar Disorder", "overall_status": "WITHDRAWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Bipolar Disorder", "Bipolar I Disorder", "Bipolar II Disorder", "Bipolar Type I Disorder", "Bipolar Disorder Mild", "Bipolar Disorder Moderate", "Bipolar Disorder Severe" ], "interventions": [ { "name": "No intervention", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "ProgenaBiome", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 0, "start_date": "2020-03-02", "completion_date": "2030-07", "has_results": false, "last_update_posted_date": "2025-06-05", "last_synced_at": "2026-05-22T03:07:12.806Z", "location_count": 1, "location_summary": "Ventura, California", "locations": [ { "city": "Ventura", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04211428" }, { "nct_id": "NCT05705063", "title": "Impact of a Ketogenic Diet on Metabolic and Psychiatric Health in Patients With Bipolar Illness", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Bipolar Disorder I", "Bipolar II Disorder", "Bipolar I Disorder", "Bipolar Disorder", "Bipolar Depression", "Bipolar and Related Disorders", "Bipolar Disorder, Type 1", "Bipolar Disorder, Type 2", "Bipolar Disorder, Mixed", "Obesity", "Metabolic Syndrome", "Ketogenic Dieting", "Weight Gain", "Brain Metabolic Disorder", "Psychotropic Agents Causing Adverse Effects in Therapeutic Use" ], "interventions": [ { "name": "LCHF Ketogenic Diet", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Stanford University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 30, "start_date": "2023-01-30", "completion_date": "2024-12-30", "has_results": false, "last_update_posted_date": "2023-01-30", "last_synced_at": "2026-05-22T03:07:12.806Z", "location_count": 1, "location_summary": "Stanford, California", "locations": [ { "city": "Stanford", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05705063" }, { "nct_id": "NCT06423794", "title": "BHV-7000 Open-Label Extension Bipolar Mania Study", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "BHV-7000", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Biohaven Therapeutics Ltd.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 94, "start_date": "2024-06-24", "completion_date": "2025-04-25", "has_results": false, "last_update_posted_date": "2025-12-16", "last_synced_at": "2026-05-22T03:07:12.806Z", "location_count": 32, "location_summary": "Bentonville, Arkansas • Little Rock, Arkansas • Rogers, Arkansas + 26 more", "locations": [ { "city": "Bentonville", "state": "Arkansas" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Rogers", "state": "Arkansas" }, { "city": "Anaheim", "state": "California" }, { "city": "Bellflower", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06423794" } ] }