{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Bipolar+Disorder+Depression", "query": { "condition": "Bipolar Disorder Depression" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 457, "total_pages": 46, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Bipolar+Disorder+Depression&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-06-10T22:14:54.562Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02041962", "title": "Implementing Health Plan-Level Care Management for Solo & Small Practices", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Bipolar Disorder", "Depression" ], "interventions": [ { "name": "Chronic Care Model for Mood Disorders", "type": "BEHAVIORAL" }, { "name": "Educational Control", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "OTHER" ], "sponsor": "University of Michigan", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "21 Years to 99 Years" }, "enrollment_count": 280, "start_date": "2014-07", "completion_date": "2018-01", "has_results": true, "last_update_posted_date": "2019-04-23", "last_synced_at": "2026-06-10T22:14:54.562Z", "location_count": 1, "location_summary": "Ann Arbor, Michigan", "locations": [ { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT02041962" }, { "nct_id": "NCT01259427", "title": "Reducing Internalized Stigma in People With Serious Mental Illness", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Schizophrenia", "Schizoaffective Disorder", "Bipolar Disorder", "Major Depression With Psychotic Features" ], "interventions": [ { "name": "Ending Self Stigma (ESS)", "type": "BEHAVIORAL" }, { "name": "Health and Wellness Group", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "VA Office of Research and Development", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 252, "start_date": "2011-10", "completion_date": "2015-09", "has_results": true, "last_update_posted_date": "2016-03-08", "last_synced_at": "2026-06-10T22:14:54.562Z", "location_count": 3, "location_summary": "Washington D.C., District of Columbia • Baltimore, Maryland • Perry Point, Maryland", "locations": [ { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Baltimore", "state": "Maryland" }, { "city": "Perry Point", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT01259427" }, { "nct_id": "NCT00075296", "title": "FMRI Study of Performance During a Probabilistic Reversal Learning Task in Depression", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Major Depressive Disorder" ], "interventions": [], "intervention_types": [], "sponsor": "National Institute of Mental Health (NIMH)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 100, "start_date": "2004-01-05", "completion_date": "2008-04-21", "has_results": false, "last_update_posted_date": "2017-07-02", "last_synced_at": "2026-06-10T22:14:54.562Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00075296" }, { "nct_id": "NCT03396068", "title": "NRX-101 for Maintenance of Remission From Severe Bipolar Depression in Patients With Suicidal Ideation", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar Depression", "Suicidal Ideation" ], "interventions": [ { "name": "NRX-101", "type": "DRUG" }, { "name": "Lurasidone HCl", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "NeuroRx, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 72, "start_date": "2019-12-01", "completion_date": "2024-12-31", "has_results": false, "last_update_posted_date": "2024-01-19", "last_synced_at": "2026-06-10T22:14:54.562Z", "location_count": 4, "location_summary": "Birmingham, Alabama • Hollywood, Florida • Fort Worth, Texas + 1 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Hollywood", "state": "Florida" }, { "city": "Fort Worth", "state": "Texas" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03396068" }, { "nct_id": "NCT02046369", "title": "Lurasidone Pediatric Bipolar Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar I Depression" ], "interventions": [ { "name": "Lurasidone", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sumitomo Pharma America, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "10 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "10 Years to 17 Years" }, "enrollment_count": 350, "start_date": "2014-03", "completion_date": "2016-10", "has_results": true, "last_update_posted_date": "2017-12-20", "last_synced_at": "2026-06-10T22:14:54.562Z", "location_count": 30, "location_summary": "Dothan, Alabama • Culver City, California • Hartford, Connecticut + 27 more", "locations": [ { "city": "Dothan", "state": "Alabama" }, { "city": "Culver City", "state": "California" }, { "city": "Hartford", "state": "Connecticut" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Orlando", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02046369" }, { "nct_id": "NCT01121536", "title": "Extension Study of the Safety and Efficacy of Armodafinil Treatment as Adjunctive Therapy in Adults With Major Depression Associated With Bipolar I Disorder", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Depression" ], "interventions": [ { "name": "Armodafinil", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Cephalon", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 867, "start_date": "2010-04-30", "completion_date": "2013-10-31", "has_results": true, "last_update_posted_date": "2018-09-21", "last_synced_at": "2026-06-10T22:14:54.562Z", "location_count": 66, "location_summary": "Birmingham, Alabama • Anaheim, California • Cerritos, California + 50 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Anaheim", "state": "California" }, { "city": "Cerritos", "state": "California" }, { "city": "Cerritos", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01121536" }, { "nct_id": "NCT04497857", "title": "Academic-Community EPINET (AC-EPINET)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Schizophrenia", "Schizoaffective Disorder", "Schizophreniform Disorders", "Major Depression With Psychotic Features", "Bipolar Disorder With Psychotic Features" ], "interventions": [ { "name": "Coordinated Specialty Care (CSC)", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Indiana University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": "35 Years", "sex": "ALL", "summary": "16 Years to 35 Years" }, "enrollment_count": 74, "start_date": "2022-03-16", "completion_date": "2025-07-29", "has_results": false, "last_update_posted_date": "2025-12-24", "last_synced_at": "2026-06-10T22:14:54.562Z", "location_count": 6, "location_summary": "Indianapolis, Indiana • New Orleans, Louisiana • Ann Arbor, Michigan + 3 more", "locations": [ { "city": "Indianapolis", "state": "Indiana" }, { "city": "New Orleans", "state": "Louisiana" }, { "city": "Ann Arbor", "state": "Michigan" }, { "city": "Rochester", "state": "New York" }, { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT04497857" }, { "nct_id": "NCT06733558", "title": "Long-term Potentiation Disruption Underlying Cognitive Impairment in ECT", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Major Depressive Disorder", "Bipolar Disorder II" ], "interventions": [ { "name": "Electroconvulsive Therapy", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "University of New Mexico", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 0, "start_date": "2025-01-21", "completion_date": "2026-07", "has_results": false, "last_update_posted_date": "2026-01-21", "last_synced_at": "2026-06-10T22:14:54.562Z", "location_count": 1, "location_summary": "Albuquerque, New Mexico", "locations": [ { "city": "Albuquerque", "state": "New Mexico" } ], "official_url": "https://clinicaltrials.gov/study/NCT06733558" }, { "nct_id": "NCT04806620", "title": "Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Post-Acute COVID-19 Syndrome", "ME/CFS", "Rheumatic Arthritis", "Juvenile Rheumatoid Arthritis (JRA)", "Psoriatic Arthritis (PsA)", "Ankylosing Spondylitis (AS)", "Autoimmune Encephalitis", "Celiac Disease", "Celiac Disease in Children", "Chronic Lyme Disease", "Post-treatment Lyme Disease Syndrome", "Crohn's Disease", "Dysautonomia", "Anorexia Nervosa", "Bulimia Nervosa", "ARFID", "Avoidant / Restrictive Food Intake Disorder", "Ehlers Danlos Syndrome", "Endometriosis", "Fibromyalgia (FM)", "Long COVID", "Lupus", "Migraines", "Mast Cell Activation Syndrome", "Multiple Sclerosis", "Myalgic Encephalomyelitis (ME)", "Myasthenia Gravis, Generalized", "Myasthenia Gravis in Children", "Narcolepsy", "Obsessive Compulsive Disorder (OCD)", "PANDAS", "Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)", "POTS - Postural Orthostatic Tachycardia Syndrome", "General Anxiety Disorder, Social Anxiety Disorder", "PTSD - Post Traumatic Stress Disorder", "Psoriasis", "Traumatic Brain Injury", "Tourette's Syndrome", "Inflammatory Bowel Disease (IBD)", "Autoimmune Diseases", "Neurological Diseases or Conditions", "Psychiatric Disorder", "Sjogren's Syndrome", "Ulcerative Colitis and Crohn's Disease" ], "interventions": [], "intervention_types": [], "sponsor": "Brain Inflammation Collaborative", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "2 Years", "maximum_age": null, "sex": "ALL", "summary": "2 Years and older" }, "enrollment_count": 10000, "start_date": "2023-07-05", "completion_date": "2030-12-31", "has_results": false, "last_update_posted_date": "2026-01-22", "last_synced_at": "2026-06-10T22:14:54.562Z", "location_count": 1, "location_summary": "Delafield, Wisconsin", "locations": [ { "city": "Delafield", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT04806620" }, { "nct_id": "NCT02865629", "title": "N-acetylcysteine in the Treatment of Depressive Symptoms in Bipolar Offspring", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Depression" ], "interventions": [ { "name": "N-acetyl cysteine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Cincinnati", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "15 Years", "maximum_age": "24 Years", "sex": "ALL", "summary": "15 Years to 24 Years" }, "enrollment_count": 22, "start_date": "2016-08", "completion_date": "2019-09", "has_results": false, "last_update_posted_date": "2018-05-14", "last_synced_at": "2026-06-10T22:14:54.562Z", "location_count": 1, "location_summary": "Cincinnati, Ohio", "locations": [ { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02865629" } ] }