{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Bipolar+Disorder+I+and+II", "query": { "condition": "Bipolar Disorder I and II" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 66, "total_pages": 7, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Bipolar+Disorder+I+and+II&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-23T05:51:04.943Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01126827", "title": "Mindfulness-Based Cognitive Behavior Therapy for Bipolar Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Bipolar Disorder" ], "interventions": [ { "name": "Mindfulness-Based Cognitive Behavioral Therapy or Supportive Psychotherapy", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 46, "start_date": "2010-01", "completion_date": "2011-04", "has_results": false, "last_update_posted_date": "2011-07-07", "last_synced_at": "2026-09-23T05:51:04.943Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT01126827" }, { "nct_id": "NCT05064319", "title": "Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Bipolar Disorder", "Cannabis Use", "Schizoaffective Disorder, Bipolar Type", "Bipolar I Disorder", "Bipolar II Disorder", "Cannabis Use Disorder, Mild", "Cannabis Use Disorder, Moderate", "Cannabis Use Disorder, Severe" ], "interventions": [ { "name": "Gabapentin", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Medical University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 51, "start_date": "2022-02-24", "completion_date": "2026-07-31", "has_results": false, "last_update_posted_date": "2026-09-09", "last_synced_at": "2026-09-23T05:51:04.943Z", "location_count": 1, "location_summary": "Charleston, South Carolina", "locations": [ { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT05064319" }, { "nct_id": "NCT04031469", "title": "A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease", "overall_status": "SUSPENDED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Gut Microbiome", "Gastrointestinal Microbiome", "Autism", "Autism Spectrum Disorder", "Autism Spectrum Disorder High-Functioning", "Alzheimer Disease", "Alzheimer Dementia (AD)", "Alzheimer Dementia", "Alzheimer Disease (AD)", "Crohn", "Crohn Colitis", "Crohn Disease (CD)", "Crohn Disease Colon", "Myalgic Encephalomyelitis", "ME/CFS", "Myalgic Encephalomyelitis (ME)", "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome", "Psoriasis", "Psoriasis Annularis", "Psoriasis Chronic", "Chronic Urinary Tract Infection", "Ulcerative Colitis (Disorder)", "Ulcerative Colitis (UC)", "Ulcerative Colitis Acute", "Ulcerative Colitis Chronic", "Multiple Sclerosis", "Multiple Sclerosis (MS) - Relapsing-remitting", "Multiple Sclerosis (MS) Primary Progressive", "Constipation Chronic Idiopathic", "Constipation", "Celiac", "Celiac Disease", "Celiac Sprue", "Lyme Arthritis", "Lyme Borreliosis, Nervous System", "Lyme Disease, Chronic", "Cholesterol", "Cholesterol Level, High", "Cancer", "Colon Cancer", "Amyotrophic Lateral Sclerosis (ALS)", "Amyotrophic Lateral Sclerosis", "Rheumatoid Arthritis (RA)", "Rheumatoid Arthritis - Rheumatism", "Chronic Fatigue Syndrome (CFS)", "PARKINSON DISEASE (Disorder)", "Parkinson Disease", "Parkinson Disease (PD)", "Depression", "Major Depressive Disorder (MDD)", "Depression Disorder", "Depression in Adults", "Anxiety", "Anxiety Disorder Generalized", "Obsessive Compulsive Disorder (OCD)", "Obsessive Compulsive Disorder OCD", "Obsessive - Compulsive Disorder", "Bipolar", "Bipolar 1 Disorder", "Bipolar Disorder (BD)", "Bipolar Disorder I and II", "Bipolar and Related Disorders", "Migraine", "Migraine Disorder", "Diabetes (DM)", "Diabetes", "Lupus", "Lupus Erythematosus", "Epidermolysis Bullosa (EB)", "Mesothelioma", "Mesothelioma Malignant", "IBS (Irritable Bowel Syndrome)", "Irritable Bowel", "IBS - Irritable Bowel Syndrome", "Irritable Bowel Syndrome (IBS)", "Eczema", "Eczema Atopic Dermatitis", "Acne", "Myasthaenia Gravis", "Gout" ], "interventions": [ { "name": "There is no intervention in this study", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "ProgenaBiome", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 1000, "start_date": "2019-07-11", "completion_date": "2030-12-10", "has_results": false, "last_update_posted_date": "2026-09-21", "last_synced_at": "2026-09-23T05:51:04.943Z", "location_count": 1, "location_summary": "Ventura, California", "locations": [ { "city": "Ventura", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04031469" }, { "nct_id": "NCT06372964", "title": "Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Bipolar Depression" ], "interventions": [ { "name": "Lumateperone", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Intra-Cellular Therapies, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "10 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "10 Years to 17 Years" }, "enrollment_count": 384, "start_date": "2024-05-14", "completion_date": "2031-10-31", "has_results": false, "last_update_posted_date": "2026-08-28", "last_synced_at": "2026-09-23T05:51:04.943Z", "location_count": 56, "location_summary": "Dothan, Alabama • Little Rock, Arkansas • Anaheim, California + 38 more", "locations": [ { "city": "Dothan", "state": "Alabama" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "Anaheim", "state": "California" }, { "city": "Redlands", "state": "California" }, { "city": "Sacramento", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06372964" }, { "nct_id": "NCT00463580", "title": "A Study of Infliximab for Treatment Resistant Major Depression", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Depression" ], "interventions": [ { "name": "Infliximab", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Emory University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "25 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "25 Years to 60 Years" }, "enrollment_count": 60, "start_date": "2008-12", "completion_date": "2011-06", "has_results": true, "last_update_posted_date": "2025-07-08", "last_synced_at": "2026-09-23T05:51:04.943Z", "location_count": 1, "location_summary": "Atlanta, Georgia", "locations": [ { "city": "Atlanta", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00463580" }, { "nct_id": "NCT01841970", "title": "Safety and Efficacy Study of HET Bipolar System for Treatment of Stage I and Stage II Hemorrhoids", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Hemorrhoids, Internal" ], "interventions": [ { "name": "HET Bipolar System", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Medtronic - MITG", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 20, "start_date": "2013-04", "completion_date": "2015-01", "has_results": true, "last_update_posted_date": "2017-01-16", "last_synced_at": "2026-09-23T05:51:04.943Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01841970" }, { "nct_id": "NCT07549581", "title": "A Study of SEP-380135 in Adults With Schizophrenia or Major Depressive Episode", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Schizophrenia", "Major Depressive Disorder (MDD)", "Bipolar Disorder" ], "interventions": [ { "name": "SEP-380135", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Otsuka Pharmaceutical Development & Commercialization, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 43, "start_date": "2024-11-07", "completion_date": "2025-09-12", "has_results": false, "last_update_posted_date": "2026-04-24", "last_synced_at": "2026-09-23T05:51:04.943Z", "location_count": 1, "location_summary": "Los Alamitos, California", "locations": [ { "city": "Los Alamitos", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07549581" }, { "nct_id": "NCT07622927", "title": "FOCUS Bipolar: Families Opening Conversations for Understanding Signs", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Bipolar Disorder (BD)", "Bipolar Disorder I or II", "Bipolar Disorder Family Members", "Screening Tool" ], "interventions": [ { "name": "Co-design Workshop (Observational Procedure)", "type": "OTHER" }, { "name": "Alpha Testing (Observational Procedure)", "type": "OTHER" }, { "name": "Beta Testing (Observational Procedure)", "type": "OTHER" }, { "name": "Youth Screening Pathway & Brief Follow-Up Interview (Observational Procedure)", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Texas Southwestern Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "7 Years", "maximum_age": null, "sex": "ALL", "summary": "7 Years and older" }, "enrollment_count": 200, "start_date": "2026-03-11", "completion_date": "2027-07-31", "has_results": false, "last_update_posted_date": "2026-06-03", "last_synced_at": "2026-09-23T05:51:04.943Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07622927" }, { "nct_id": "NCT00181727", "title": "Study of Depakote ER for the Treatment of Mania in Children Ages 6-12 With Bipolar Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Bipolar Disorder", "Mania" ], "interventions": [ { "name": "divalproex sodium extended release", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": "12 Years", "sex": "ALL", "summary": "6 Years to 12 Years" }, "enrollment_count": 14, "start_date": "2004-01", "completion_date": "2006-11", "has_results": false, "last_update_posted_date": "2013-10-22", "last_synced_at": "2026-09-23T05:51:04.943Z", "location_count": 1, "location_summary": "Cambridge, Massachusetts", "locations": [ { "city": "Cambridge", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00181727" }, { "nct_id": "NCT00181779", "title": "Aripiprazole for the Treatment of Mania in Children and Adolescents With Bipolar Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Bipolar Disorder", "Mania" ], "interventions": [ { "name": "aripiprazole (Abilify)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "6 Years to 17 Years" }, "enrollment_count": 20, "start_date": "2003-02", "completion_date": "2006-12", "has_results": false, "last_update_posted_date": "2013-10-22", "last_synced_at": "2026-09-23T05:51:04.943Z", "location_count": 1, "location_summary": "Cambridge, Massachusetts", "locations": [ { "city": "Cambridge", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00181779" } ] }