{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Bone+Alteration",
    "query": {
      "condition": "Bone Alteration"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 9,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:37:35.716Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07284563",
      "title": "Ultralow Dose PET Imaging for 18F-NaF Uptake",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Healthy Volunteer",
        "Bone Alteration",
        "Bone and Joint Cancer",
        "Bone and Joint Infection",
        "Arthritis"
      ],
      "interventions": [
        {
          "name": "18F-NaF",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Akiva Mintz",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "120 Years",
        "sex": "ALL",
        "summary": "18 Years to 120 Years"
      },
      "enrollment_count": 200,
      "start_date": "2025-09-01",
      "completion_date": "2030-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-12-16",
      "last_synced_at": "2026-05-22T05:37:35.716Z",
      "location_count": 1,
      "location_summary": "Englewood, New Jersey",
      "locations": [
        {
          "city": "Englewood",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07284563"
    },
    {
      "nct_id": "NCT05253807",
      "title": "Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Relapsed or Refractory Advanced Non-Small Cell Lung Cancer With an FGFR Alteration",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Non-Small Cell Lung Cancer (NSCLC)"
      ],
      "interventions": [
        {
          "name": "Pemigatinib",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Incyte Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 8,
      "start_date": "2022-04-29",
      "completion_date": "2023-08-16",
      "has_results": true,
      "last_update_posted_date": "2025-08-05",
      "last_synced_at": "2026-05-22T05:37:35.716Z",
      "location_count": 7,
      "location_summary": "Los Angeles, California • Fort Myers, Florida • Miami, Florida + 4 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Fort Myers",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Pembroke Pines",
          "state": "Florida"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05253807"
    },
    {
      "nct_id": "NCT01921517",
      "title": "Micromechanical Modeling Using Low Magnitude Mechanical Stimulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bone Alteration"
      ],
      "interventions": [
        {
          "name": "Low Magnitude Mechanical Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Sham Low Magnitude Mechanical Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "65 Years",
        "sex": "FEMALE",
        "summary": "45 Years to 65 Years · Female only"
      },
      "enrollment_count": 117,
      "start_date": "2012-09",
      "completion_date": "2019-06-20",
      "has_results": true,
      "last_update_posted_date": "2019-11-15",
      "last_synced_at": "2026-05-22T05:37:35.716Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01921517"
    },
    {
      "nct_id": "NCT02375503",
      "title": "Efficacy of a Once Daily Calcium and Vitamin D Fortified Food Product to Improve Bone Microarchitecture",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bone Alteration",
        "Dietary Modification"
      ],
      "interventions": [
        {
          "name": "Calcium/Vitamin D",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Placebo",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "United States Army Research Institute of Environmental Medicine",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": "42 Years",
        "sex": "ALL",
        "summary": "17 Years to 42 Years"
      },
      "enrollment_count": 175,
      "start_date": "2015-04",
      "completion_date": "2015-06",
      "has_results": false,
      "last_update_posted_date": "2017-05-15",
      "last_synced_at": "2026-05-22T05:37:35.716Z",
      "location_count": 1,
      "location_summary": "Columbia, South Carolina",
      "locations": [
        {
          "city": "Columbia",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02375503"
    },
    {
      "nct_id": "NCT06999954",
      "title": "Shwachman-Diamond Syndrome Global Patient Survey and Partnering Platform",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Shwachman-Diamond Syndrome",
        "SDS",
        "IBMF",
        "Congenital Neutropenia",
        "Heme Malignancy",
        "Shwachman Syndrome",
        "Inherited Bone Marrow Failure",
        "Exocrine Pancreatic Insufficiency",
        "WHIM",
        "ELANE",
        "SBDS Gene Mutation",
        "EFL1 Gene Mutation",
        "DNAJC21 Gene Mutation",
        "SRP54 Gene Mutation",
        "Inherited Cancer Syndrome",
        "Inherited Cancer-Predisposing Syndrome",
        "Neutropenia, Severe Chronic",
        "Neutropenia Other",
        "Neutropenia Chronic Benign",
        "Ribosome Alteration",
        "Ribosomopathy",
        "Immune Deficiency",
        "Inherited BMF Syndrome",
        "Inherited Immunodeficiency Diseases",
        "Cognitive Delay, Mild",
        "Myelodysplastic Syndromes",
        "Pancytopenia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Shwachman-Diamond Syndrome Alliance Inc",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 8000,
      "start_date": "2024-02-07",
      "completion_date": "2088-12",
      "has_results": false,
      "last_update_posted_date": "2025-05-31",
      "last_synced_at": "2026-05-22T05:37:35.716Z",
      "location_count": 1,
      "location_summary": "Woburn, Massachusetts",
      "locations": [
        {
          "city": "Woburn",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06999954"
    },
    {
      "nct_id": "NCT04040205",
      "title": "Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Chondrosarcoma",
        "Osteosarcoma",
        "Soft Tissue Sarcoma"
      ],
      "interventions": [
        {
          "name": "Abemaciclib",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 44,
      "start_date": "2019-10-07",
      "completion_date": "2027-06-01",
      "has_results": false,
      "last_update_posted_date": "2025-07-20",
      "last_synced_at": "2026-05-22T05:37:35.716Z",
      "location_count": 4,
      "location_summary": "Jacksonville, Florida • Iowa City, Iowa • St Louis, Missouri + 1 more",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04040205"
    },
    {
      "nct_id": "NCT06239272",
      "title": "NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Adipocytic Neoplasm",
        "Liposarcoma",
        "Atypical Fibroxanthoma",
        "Angiomatoid Fibrous Histiocytoma",
        "Myoepithelioma",
        "Fibrosarcoma NOS",
        "Myxofibrosarcoma",
        "Angiosarcoma",
        "Osteosarcoma, Extraskeletal"
      ],
      "interventions": [
        {
          "name": "Surgical resection",
          "type": "PROCEDURE"
        },
        {
          "name": "Proton beam radiation therapy",
          "type": "RADIATION"
        },
        {
          "name": "Pazopanib",
          "type": "DRUG"
        },
        {
          "name": "Ifosfamide",
          "type": "DRUG"
        },
        {
          "name": "Doxorubicin",
          "type": "DRUG"
        },
        {
          "name": "Selinexor",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "RADIATION",
        "DRUG"
      ],
      "sponsor": "St. Jude Children's Research Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "Up to 30 Years"
      },
      "enrollment_count": 139,
      "start_date": "2024-03-27",
      "completion_date": "2037-06",
      "has_results": false,
      "last_update_posted_date": "2026-05-19",
      "last_synced_at": "2026-05-22T05:37:35.716Z",
      "location_count": 6,
      "location_summary": "Chicago, Illinois • Baton Rouge, Louisiana • Boston, Massachusetts + 3 more",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Baton Rouge",
          "state": "Louisiana"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06239272"
    },
    {
      "nct_id": "NCT01327274",
      "title": "Multicenter Trial of Magnetic Mini-Mover for Pectus Excavatum",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pectus Excavatum"
      ],
      "interventions": [
        {
          "name": "Magnetic Mini-Mover Procedure (Magnimplant)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Michael Harrison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "14 Years",
        "sex": "ALL",
        "summary": "8 Years to 14 Years"
      },
      "enrollment_count": 15,
      "start_date": "2011-12",
      "completion_date": "2018-05",
      "has_results": true,
      "last_update_posted_date": "2018-11-08",
      "last_synced_at": "2026-05-22T05:37:35.716Z",
      "location_count": 3,
      "location_summary": "Sacramento, California • San Francisco, California • Kansas City, Missouri",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01327274"
    },
    {
      "nct_id": "NCT00466206",
      "title": "Magnetic Mini-Mover Procedure to Treat Pectus Excavatum",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Pectus Excavatum"
      ],
      "interventions": [
        {
          "name": "Magnetic Mini-Mover Procedure (3MP)",
          "type": "DEVICE"
        },
        {
          "name": "Magnatract (external magnet in a removable external brace)",
          "type": "DEVICE"
        },
        {
          "name": "3MP (Magnetic Mini-Mover Procedure)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "14 Years",
        "sex": "ALL",
        "summary": "8 Years to 14 Years"
      },
      "enrollment_count": 10,
      "start_date": "2007-04",
      "completion_date": "2011-04",
      "has_results": true,
      "last_update_posted_date": "2016-01-01",
      "last_synced_at": "2026-05-22T05:37:35.716Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00466206"
    }
  ]
}