{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Bone+Necrosis&page=2",
    "query": {
      "condition": "Bone Necrosis",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Bone+Necrosis&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T18:25:48.115Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00765362",
      "title": "Mobile - Bearing Knee Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Inflammatory Tissue Disorder",
        "Osteoarthritis",
        "Avascular Necrosis",
        "Post-traumatic Arthritis",
        "Secondary Arthritis"
      ],
      "interventions": [
        {
          "name": "Encore Mobile-Bearing Knee",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Encore Medical, L.P.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 419,
      "start_date": "2000-01",
      "completion_date": "2008-08",
      "has_results": true,
      "last_update_posted_date": "2011-05-11",
      "last_synced_at": "2026-06-10T18:25:48.115Z",
      "location_count": 8,
      "location_summary": "Phoenix, Arizona • Fountain Valley, California • Miami, Florida + 5 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Fountain Valley",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Garden City",
          "state": "Michigan"
        },
        {
          "city": "Hilton Head Island",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00765362"
    },
    {
      "nct_id": "NCT05787821",
      "title": "Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Knee Pain Chronic",
        "Osteoarthritis, Knee",
        "Rheumatoid Arthritis",
        "Traumatic Arthritis",
        "Polyarthritis",
        "Varus Deformity",
        "Valgus Deformity",
        "Flexion Deformity of Knee",
        "Avascular Necrosis"
      ],
      "interventions": [
        {
          "name": "Total Knee Arthroplasty",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 760,
      "start_date": "2023-06-28",
      "completion_date": "2035-06",
      "has_results": false,
      "last_update_posted_date": "2026-01-20",
      "last_synced_at": "2026-06-10T18:25:48.115Z",
      "location_count": 16,
      "location_summary": "Parker, Colorado • Tampa, Florida • Atlanta, Georgia + 13 more",
      "locations": [
        {
          "city": "Parker",
          "state": "Colorado"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05787821"
    },
    {
      "nct_id": "NCT03226808",
      "title": "Vivacit-E Post-market Follow-up Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis",
        "Avascular Necrosis of Bone of Hip",
        "Post-traumatic; Arthrosis",
        "Congenital Hip Dysplasia"
      ],
      "interventions": [
        {
          "name": "Vivacit-E Liner",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 258,
      "start_date": "2013-10-01",
      "completion_date": "2028-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-01-01",
      "last_synced_at": "2026-06-10T18:25:48.115Z",
      "location_count": 5,
      "location_summary": "Parker, Colorado • Chapel Hill, North Carolina • Charlotte, North Carolina + 2 more",
      "locations": [
        {
          "city": "Parker",
          "state": "Colorado"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03226808"
    },
    {
      "nct_id": "NCT01875458",
      "title": "Biomarker Identification in Orthopaedic & Oral Maxillofacial Surgery Subjects to Identify Risks of Bisphosphonate Use",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Osteoporosis, With or Without Treatment",
        "Bisphosphonate Treatment",
        "Atypical Femur Fracture",
        "Bisphosphonate Related Osteonecrosis of the Jaws (BRONJ)",
        "Healthy Volunteers"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 314,
      "start_date": "2012-04-13",
      "completion_date": "2022-10-30",
      "has_results": false,
      "last_update_posted_date": "2023-01-13",
      "last_synced_at": "2026-06-10T18:25:48.115Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01875458"
    },
    {
      "nct_id": "NCT00505219",
      "title": "Ixmyelocel-T Treatment of Patients With Osteonecrosis of the Femoral Head",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Osteonecrosis"
      ],
      "interventions": [
        {
          "name": "Ixmyelocel-T",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Standard of Care Only",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "Vericel Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 11,
      "start_date": "2007-09",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2019-10-21",
      "last_synced_at": "2026-06-10T18:25:48.115Z",
      "location_count": 3,
      "location_summary": "Baltimore, Maryland • Minneapolis, Minnesota • Brooklyn, New York",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Brooklyn",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00505219"
    },
    {
      "nct_id": "NCT00006130",
      "title": "Decompression Coring Versus Conservative Therapy in Patients With Avascular Necrosis of the Hip Related to Sickle Cell Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bone Avascular Necrosis",
        "Sickle Cell Anemia"
      ],
      "interventions": [
        {
          "name": "Core decompression",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "UCSF Benioff Children's Hospital Oakland",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "10 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "1999-06",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2017-02-15",
      "last_synced_at": "2026-06-10T18:25:48.115Z",
      "location_count": 2,
      "location_summary": "Oakland, California • Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00006130"
    },
    {
      "nct_id": "NCT03245320",
      "title": "Clinical Evaluation of the TITAN™ Total Shoulder System",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Arthritis",
        "Arthritis, Degenerative",
        "Rheumatoid Arthritis",
        "Post-traumatic Arthrosis of Other Joints, Shoulder Region",
        "Rotator Cuff Syndrome of Shoulder and Allied Disorders",
        "Fracture",
        "Avascular Necrosis",
        "Joint Instability",
        "Joint Trauma",
        "Dislocation, Shoulder",
        "Pain, Shoulder"
      ],
      "interventions": [
        {
          "name": "Integra TITAN™ Total Shoulder Generation 1.0",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Smith & Nephew, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2017-03-20",
      "completion_date": "2022-06-23",
      "has_results": false,
      "last_update_posted_date": "2023-12-21",
      "last_synced_at": "2026-06-10T18:25:48.115Z",
      "location_count": 2,
      "location_summary": "Indianapolis, Indiana • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03245320"
    },
    {
      "nct_id": "NCT07104279",
      "title": "Z1 Hip System: Post-Market Clinical Follow Up Study",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hip Osteoarthritis",
        "Acute Traumatic Fracture of the Femoral Head or Neck",
        "Avascular Necrosis of the Femoral Head"
      ],
      "interventions": [
        {
          "name": "Z1 Femoral Hip System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2025-10-13",
      "completion_date": "2031-08",
      "has_results": false,
      "last_update_posted_date": "2025-11-10",
      "last_synced_at": "2026-06-10T18:25:48.115Z",
      "location_count": 2,
      "location_summary": "Charlotte, North Carolina • Portland, Oregon",
      "locations": [
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07104279"
    },
    {
      "nct_id": "NCT04754087",
      "title": "G7 Acetabular System With Vivacit-E or Longevity Liner PMCF Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Total Hip Arthroplasty",
        "Degenerative Joint Disease of Hip",
        "Avascular Necrosis of Hip",
        "Rheumatoid Arthritis of Hip",
        "Osteoarthritis, Hip",
        "Osteoarthritis of Hip",
        "Fractures, Hip",
        "Fracture of Hip"
      ],
      "interventions": [
        {
          "name": "Vivacit-E and Longevity (HXLPE) Liners",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2021-07-07",
      "completion_date": "2033-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-06-18",
      "last_synced_at": "2026-06-10T18:25:48.115Z",
      "location_count": 6,
      "location_summary": "Denver, Colorado • South Bend, Indiana • Durham, North Carolina + 3 more",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "South Bend",
          "state": "Indiana"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Eugene",
          "state": "Oregon"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04754087"
    },
    {
      "nct_id": "NCT00764673",
      "title": "The 3DKnee™ System: A Post-Market Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Osteoarthritis",
        "Rheumatoid Arthritis",
        "Post Traumatic Arthritis",
        "Varus Deformity",
        "Avascular Necrosis"
      ],
      "interventions": [
        {
          "name": "3DKnee",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Encore Medical, L.P.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 71,
      "start_date": "2006-10",
      "completion_date": "2010-10",
      "has_results": true,
      "last_update_posted_date": "2011-03-02",
      "last_synced_at": "2026-06-10T18:25:48.115Z",
      "location_count": 1,
      "location_summary": "City of Saint Peters, Missouri",
      "locations": [
        {
          "city": "City of Saint Peters",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00764673"
    }
  ]
}