{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Bothersome+Symptoms",
    "query": {
      "condition": "Bothersome Symptoms"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:26:17.189Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03711630",
      "title": "Impact of Meditation on Bothersome Tinnitus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tinnitus",
        "Noise Induced Tinnitus",
        "Tinnitus, Subjective",
        "Tinnitus, Objective",
        "Tinnitus Aggravated",
        "Tinnitus, Pulsatile",
        "Tinnitus, Spontaneous Oto-Acoustic Emission",
        "Tinnitus, Clicking",
        "Tinnitus, Tensor Tympani Induced"
      ],
      "interventions": [
        {
          "name": "Meditation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "State University of New York at Buffalo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 27,
      "start_date": "2018-10-06",
      "completion_date": "2020-03-21",
      "has_results": false,
      "last_update_posted_date": "2020-10-22",
      "last_synced_at": "2026-05-22T05:26:17.189Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03711630"
    },
    {
      "nct_id": "NCT01726270",
      "title": "An 8-week, Open-label, Uncontrolled Study of Tamsulosin 0.4mg in Men With Bothersome Urinary Symptoms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Lower Urinary Tract Symptoms"
      ],
      "interventions": [
        {
          "name": "tamsulosin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boehringer Ingelheim",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "MALE",
        "summary": "18 Years to 100 Years · Male only"
      },
      "enrollment_count": 689,
      "start_date": "2012-11",
      "completion_date": "2013-03",
      "has_results": true,
      "last_update_posted_date": "2020-03-27",
      "last_synced_at": "2026-05-22T05:26:17.189Z",
      "location_count": 18,
      "location_summary": "Hoover, Alabama • Mesa, Arizona • Encino, California + 15 more",
      "locations": [
        {
          "city": "Hoover",
          "state": "Alabama"
        },
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Encino",
          "state": "California"
        },
        {
          "city": "Garden Grove",
          "state": "California"
        },
        {
          "city": "La Habra",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01726270"
    },
    {
      "nct_id": "NCT02191592",
      "title": "EMA-Defined Tinnitus Subgroups",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Tinnitus"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 40,
      "start_date": "2014-07",
      "completion_date": "2016-02",
      "has_results": false,
      "last_update_posted_date": "2016-03-02",
      "last_synced_at": "2026-05-22T05:26:17.189Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02191592"
    },
    {
      "nct_id": "NCT03904264",
      "title": "Feasibility and Acceptability of Using Low-Gain Hearing Aids for Bothersome Tinnitus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tinnitus",
        "Hearing Aids",
        "Normal Hearing"
      ],
      "interventions": [
        {
          "name": "Receiver in the canal (RIC) hearing aids",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2020-02-24",
      "completion_date": "2022-09-30",
      "has_results": true,
      "last_update_posted_date": "2023-11-21",
      "last_synced_at": "2026-05-22T05:26:17.189Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03904264"
    },
    {
      "nct_id": "NCT04864223",
      "title": "Classifying and Predicting Long-term Pain and Function in Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Pain",
        "Pain"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 6783,
      "start_date": "2018-08-01",
      "completion_date": "2020-07-31",
      "has_results": false,
      "last_update_posted_date": "2021-04-28",
      "last_synced_at": "2026-05-22T05:26:17.189Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04864223"
    },
    {
      "nct_id": "NCT01550796",
      "title": "Treatment of Chronic Bothersome Tinnitus Using Cognitive Training and D-cycloserine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Tinnitus"
      ],
      "interventions": [
        {
          "name": "Cognitive Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "35 Years to 65 Years"
      },
      "enrollment_count": 37,
      "start_date": "2012-01",
      "completion_date": "2012-06",
      "has_results": false,
      "last_update_posted_date": "2013-05-23",
      "last_synced_at": "2026-05-22T05:26:17.189Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01550796"
    },
    {
      "nct_id": "NCT01978002",
      "title": "Sensory Sensitivity and Urinary Symptoms in the Female Population",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bladder Pain and Discomfort",
        "Urinary Urgency and Frequency",
        "Bothersome Symptoms"
      ],
      "interventions": [
        {
          "name": "Pain sensitivity testing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Urodynamic testing",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 26,
      "start_date": "2011-11",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2016-04-13",
      "last_synced_at": "2026-05-22T05:26:17.189Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01978002"
    },
    {
      "nct_id": "NCT06049797",
      "title": "A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hot Flashes"
      ],
      "interventions": [
        {
          "name": "Fezolinetant",
          "type": "DRUG"
        },
        {
          "name": "Paroxetine",
          "type": "DRUG"
        },
        {
          "name": "Citalopram",
          "type": "DRUG"
        },
        {
          "name": "Escitalopram",
          "type": "DRUG"
        },
        {
          "name": "Desvenlafaxine",
          "type": "DRUG"
        },
        {
          "name": "Venlafaxine",
          "type": "DRUG"
        },
        {
          "name": "Gabapentin",
          "type": "DRUG"
        },
        {
          "name": "Clonidine",
          "type": "DRUG"
        },
        {
          "name": "Pregabalin",
          "type": "DRUG"
        },
        {
          "name": "Oxybutynin",
          "type": "DRUG"
        },
        {
          "name": "Any other SSRI/SNRI not already specified",
          "type": "DRUG"
        },
        {
          "name": "Any other non-hormonal pharmacologic therapy prescribed for the treatment of VMS not included in a category above",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Astellas Pharma Global Development, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 75 Years · Female only"
      },
      "enrollment_count": 999,
      "start_date": "2023-11-15",
      "completion_date": "2026-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-29",
      "last_synced_at": "2026-05-22T05:26:17.189Z",
      "location_count": 48,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Lomita, California + 39 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Lomita",
          "state": "California"
        },
        {
          "city": "Pomona",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06049797"
    },
    {
      "nct_id": "NCT01385540",
      "title": "Exploration of Cortical Neural Network in Patients With Bothersome Tinnitus",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Tinnitus"
      ],
      "interventions": [
        {
          "name": "Task-Based Functional Magnetic Resonance Imaging (fMRI)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 7,
      "start_date": "2011-07",
      "completion_date": "2011-08",
      "has_results": false,
      "last_update_posted_date": "2012-03-02",
      "last_synced_at": "2026-05-22T05:26:17.189Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01385540"
    },
    {
      "nct_id": "NCT01166438",
      "title": "Anticholinergic vs. Botox Comparison Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Urge Urinary Incontinence",
        "Overactive Bladder"
      ],
      "interventions": [
        {
          "name": "Botulinum toxin A (Botox A®)",
          "type": "DRUG"
        },
        {
          "name": "Solifenacin 5mg",
          "type": "DRUG"
        },
        {
          "name": "Solifenacin 10mg",
          "type": "DRUG"
        },
        {
          "name": "Trospium chloride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NICHD Pelvic Floor Disorders Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "21 Years and older · Female only"
      },
      "enrollment_count": 249,
      "start_date": "2010-03",
      "completion_date": "2012-05",
      "has_results": true,
      "last_update_posted_date": "2018-05-02",
      "last_synced_at": "2026-05-22T05:26:17.189Z",
      "location_count": 11,
      "location_summary": "Birmingham, Alabama • La Jolla, California • San Diego, California + 8 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Maywood",
          "state": "Illinois"
        },
        {
          "city": "Dearborn",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01166438"
    }
  ]
}