{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Brain+Hypoxia",
    "query": {
      "condition": "Brain Hypoxia"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 134,
    "total_pages": 14,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Brain+Hypoxia&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T19:04:33.278Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04337697",
      "title": "Neonatal Seizure Registry - Developmental Functional EValuation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neonatal Seizure",
        "Hypoxic-Ischemic Encephalopathy",
        "Stroke",
        "Intracranial Hemorrhages",
        "Epilepsy",
        "Cerebral Palsy",
        "Intellectual Disability"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "8 Years",
        "sex": "ALL",
        "summary": "2 Years to 8 Years"
      },
      "enrollment_count": 188,
      "start_date": "2020-03-15",
      "completion_date": "2025-03-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-05",
      "last_synced_at": "2026-06-10T19:04:33.278Z",
      "location_count": 9,
      "location_summary": "San Francisco, California • Stanford, California • Washington D.C., District of Columbia + 5 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04337697"
    },
    {
      "nct_id": "NCT07262060",
      "title": "Improving Preterm Kidney Outcomes With Caffeine",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Kidney Injury",
        "Pre-Term"
      ],
      "interventions": [
        {
          "name": "Caffeine citrate",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Hours",
        "maximum_age": "96 Hours",
        "sex": "ALL",
        "summary": "12 Hours to 96 Hours"
      },
      "enrollment_count": 114,
      "start_date": "2026-05-28",
      "completion_date": "2030-09",
      "has_results": false,
      "last_update_posted_date": "2026-06-04",
      "last_synced_at": "2026-06-10T19:04:33.278Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07262060"
    },
    {
      "nct_id": "NCT03268590",
      "title": "Neuroimaging During Pure Oxygen Breathing",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hyperoxia",
        "Hypoxia, Brain",
        "Neurobehavioral Manifestations"
      ],
      "interventions": [
        {
          "name": "Oxygen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Case Western Reserve University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 33,
      "start_date": "2017-10-02",
      "completion_date": "2018-05-09",
      "has_results": true,
      "last_update_posted_date": "2019-11-13",
      "last_synced_at": "2026-06-10T19:04:33.278Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03268590"
    },
    {
      "nct_id": "NCT00830453",
      "title": "Hyperbaric Oxygen Therapy in Chronic Stable Brain Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Brain Injury",
        "Sequelae",
        "Stroke",
        "Anoxia",
        "Trauma"
      ],
      "interventions": [
        {
          "name": "Hyperbaric oxygen therapy (HBO2)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Intermountain Health Care, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 63,
      "start_date": "2003-11",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2021-02-15",
      "last_synced_at": "2026-06-10T19:04:33.278Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00830453"
    },
    {
      "nct_id": "NCT04217551",
      "title": "Influence of Cooling Duration on Efficacy in Cardiac Arrest Patients",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiac Arrest, Out-Of-Hospital",
        "Hypothermia, Induced",
        "Hypoxia-Ischemia, Brain"
      ],
      "interventions": [
        {
          "name": "Therapeutic Hypothermia",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1158,
      "start_date": "2020-05-18",
      "completion_date": "2025-09-05",
      "has_results": false,
      "last_update_posted_date": "2025-06-25",
      "last_synced_at": "2026-06-10T19:04:33.278Z",
      "location_count": 76,
      "location_summary": "Birmingham, Alabama • Tucson, Arizona • Los Angeles, California + 57 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04217551"
    },
    {
      "nct_id": "NCT03145142",
      "title": "PREMOD2 With Near Infrared Spectroscopy Sub-study",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypoxia, Brain",
        "Premature Birth"
      ],
      "interventions": [
        {
          "name": "Umbilical cord milking",
          "type": "PROCEDURE"
        },
        {
          "name": "Delayed Cord Clamping",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Sharp HealthCare",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "23 Weeks",
        "maximum_age": "28 Weeks",
        "sex": "ALL",
        "summary": "23 Weeks to 28 Weeks"
      },
      "enrollment_count": 121,
      "start_date": "2017-06-06",
      "completion_date": "2024-12-15",
      "has_results": false,
      "last_update_posted_date": "2021-12-13",
      "last_synced_at": "2026-06-10T19:04:33.278Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03145142"
    },
    {
      "nct_id": "NCT03743805",
      "title": "Rapid Reversal of CNS-Depressant Drug Effect Prior to Brain Death Determination",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Brain Death",
        "Anoxic Brain Injury",
        "Cardiac Arrest",
        "Sedative Intoxication",
        "Narcotic Intoxication"
      ],
      "interventions": [
        {
          "name": "Flumazenil",
          "type": "DRUG"
        },
        {
          "name": "Naloxone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Prisma Health-Midlands",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2019-01-01",
      "completion_date": "2021-07-21",
      "has_results": false,
      "last_update_posted_date": "2024-10-31",
      "last_synced_at": "2026-06-10T19:04:33.278Z",
      "location_count": 1,
      "location_summary": "Columbia, South Carolina",
      "locations": [
        {
          "city": "Columbia",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03743805"
    },
    {
      "nct_id": "NCT01866657",
      "title": "Cerebral Oximetry in Single Lung Ventilation Thoracic Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypoxia"
      ],
      "interventions": [
        {
          "name": "Vasoconstrictor Agents",
          "type": "DRUG"
        },
        {
          "name": "Head/neck repositioning",
          "type": "OTHER"
        },
        {
          "name": "Increase ETCO2",
          "type": "OTHER"
        },
        {
          "name": "IV fluid bolus",
          "type": "OTHER"
        },
        {
          "name": "Additional anesthesia",
          "type": "DRUG"
        },
        {
          "name": "RBC transfusion",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Increase FiO2",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "BIOLOGICAL"
      ],
      "sponsor": "University Hospitals Cleveland Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 74,
      "start_date": "2013-06",
      "completion_date": "2016-11-10",
      "has_results": true,
      "last_update_posted_date": "2022-07-05",
      "last_synced_at": "2026-06-10T19:04:33.278Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01866657"
    },
    {
      "nct_id": "NCT04019522",
      "title": "American Heart Association- Stroke/Hypoxia Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stroke"
      ],
      "interventions": [
        {
          "name": "Acute Intermittent Hypoxia (AIH)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Shirley Ryan AbilityLab",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 16,
      "start_date": "2019-07-15",
      "completion_date": "2025-07-01",
      "has_results": true,
      "last_update_posted_date": "2026-04-07",
      "last_synced_at": "2026-06-10T19:04:33.278Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04019522"
    },
    {
      "nct_id": "NCT07628829",
      "title": "Neonatal Neurological Observation With Video AI",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neonatal Encephalopathy",
        "Hypoxic-Ischemic Encephalopathy",
        "Sedation",
        "Sleep"
      ],
      "interventions": [
        {
          "name": "Continuous bedside video monitoring with AI anatomic landmark tracking for neurologic monitoring",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Artemis AI Labs",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 200,
      "start_date": "2026-06-01",
      "completion_date": "2029-05-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-08",
      "last_synced_at": "2026-06-10T19:04:33.278Z",
      "location_count": 2,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07628829"
    }
  ]
}