{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Brain+Ischemia",
    "query": {
      "condition": "Brain Ischemia"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 895,
    "total_pages": 90,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Brain+Ischemia&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T11:18:10.848Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04157270",
      "title": "LOTUS: Global Acute Stroke Study Utilizing Penumbra System",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Stroke, Ischemic"
      ],
      "interventions": [
        {
          "name": "Penumbra System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Penumbra Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 23,
      "start_date": "2020-01-12",
      "completion_date": "2021-05-10",
      "has_results": false,
      "last_update_posted_date": "2021-06-25",
      "last_synced_at": "2026-06-26T11:18:10.848Z",
      "location_count": 2,
      "location_summary": "Englewood, Colorado • Tampa, Florida",
      "locations": [
        {
          "city": "Englewood",
          "state": "Colorado"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04157270"
    },
    {
      "nct_id": "NCT02478177",
      "title": "Addressing Real-world Anticoagulant Management Issues in Stroke",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Stroke",
        "Cerebrovascular Stroke",
        "Intracerebral Hemorrhage"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6000,
      "start_date": "2015-09",
      "completion_date": "2019-12",
      "has_results": false,
      "last_update_posted_date": "2020-02-26",
      "last_synced_at": "2026-06-26T11:18:10.848Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02478177"
    },
    {
      "nct_id": "NCT00071032",
      "title": "Safety and Effectiveness of Two Blood Transfusion Strategies in Surgical Patients With Cardiovascular Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Anemia",
        "Hematologic Diseases",
        "Cardiovascular Diseases",
        "Heart Diseases",
        "Myocardial Infarction",
        "Thromboembolism",
        "Pneumonia",
        "Cerebrovascular Accident"
      ],
      "interventions": [
        {
          "name": "Liberal (10 g/dL) Transfusion Strategy",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Restrictive (Symptomatic) Transfusion Strategy",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 2016,
      "start_date": "2003-07",
      "completion_date": "2009-05",
      "has_results": true,
      "last_update_posted_date": "2020-11-16",
      "last_synced_at": "2026-06-26T11:18:10.848Z",
      "location_count": 1,
      "location_summary": "New Brunswick, New Jersey",
      "locations": [
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00071032"
    },
    {
      "nct_id": "NCT00383305",
      "title": "CoolCap Trial, Treatment of Perinatal Hypoxic-Ischemic Encephalopathy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neonatal Hypoxic-Ischemic Encephalopathy (HIE)"
      ],
      "interventions": [
        {
          "name": "Cool-Cap",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Olympic Medical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Hour",
        "maximum_age": "6 Hours",
        "sex": "ALL",
        "summary": "1 Hour to 6 Hours"
      },
      "enrollment_count": 235,
      "start_date": "1999-07",
      "completion_date": "2003-09",
      "has_results": false,
      "last_update_posted_date": "2006-10-03",
      "last_synced_at": "2026-06-26T11:18:10.848Z",
      "location_count": 19,
      "location_summary": "Little Rock, Arkansas • Oakland, California • San Diego, California + 15 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00383305"
    },
    {
      "nct_id": "NCT04221256",
      "title": "Dose-finding Study of Selective Serotonin Reuptake Inhibitors to Enhance Neuroplasticity",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Stroke, Ischemic"
      ],
      "interventions": [
        {
          "name": "Administration of SSRI escitalopram",
          "type": "DRUG"
        },
        {
          "name": "Paired Associative stimulation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Administration of Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Burke Medical Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2020-03-11",
      "completion_date": "2021-02-09",
      "has_results": false,
      "last_update_posted_date": "2021-07-23",
      "last_synced_at": "2026-06-26T11:18:10.848Z",
      "location_count": 1,
      "location_summary": "White Plains, New York",
      "locations": [
        {
          "city": "White Plains",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04221256"
    },
    {
      "nct_id": "NCT00879892",
      "title": "Effect of Xenon and Therapeutic Hypothermia, on the Brain and on Neurological Outcome Following Brain Ischemia in Cardiac Arrest Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Ischemic Brain Injury"
      ],
      "interventions": [
        {
          "name": "xenon",
          "type": "DRUG"
        },
        {
          "name": "Hypothermia",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Turku University Hospital",
      "sponsor_class": "OTHER_GOV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 110,
      "start_date": "2009-05",
      "completion_date": "2014-09",
      "has_results": false,
      "last_update_posted_date": "2015-01-19",
      "last_synced_at": "2026-06-26T11:18:10.848Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00879892"
    },
    {
      "nct_id": "NCT01985100",
      "title": "The Use of Hyperbaric Oxygen to Increase the Blood Supply in the Injured, But Still Alive Tissue, Around an Old Stroke",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ischemic Cerebrovascular Accident"
      ],
      "interventions": [
        {
          "name": "hyperbaric oxygen chamber",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "John Davidson",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "50 Years to 80 Years"
      },
      "enrollment_count": 0,
      "start_date": "2013-11-21",
      "completion_date": "2014-09-27",
      "has_results": false,
      "last_update_posted_date": "2017-10-27",
      "last_synced_at": "2026-06-26T11:18:10.848Z",
      "location_count": 1,
      "location_summary": "Chesterfield, Missouri",
      "locations": [
        {
          "city": "Chesterfield",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01985100"
    },
    {
      "nct_id": "NCT01599195",
      "title": "Use of Amplified Sound Signal to Identify Presence of Carotid and Femoral Stenosis",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Carotid Stenosis",
        "Femoral Arterial Stenosis",
        "Carotid Bruit Asymptomatic",
        "Carotid Murmur"
      ],
      "interventions": [
        {
          "name": "AudioDoc",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Albert Einstein Healthcare Network",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "19 Years to 90 Years"
      },
      "enrollment_count": 18,
      "start_date": "2010-04",
      "completion_date": "2017-01",
      "has_results": false,
      "last_update_posted_date": "2017-02-01",
      "last_synced_at": "2026-06-26T11:18:10.848Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01599195"
    },
    {
      "nct_id": "NCT01423201",
      "title": "Transient Ischemic Attack (TIA) Triage and Evaluation of Stroke Risk",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cerebrovascular Accident"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 262,
      "start_date": "2010-09",
      "completion_date": "2017-11-02",
      "has_results": false,
      "last_update_posted_date": "2019-04-11",
      "last_synced_at": "2026-06-26T11:18:10.848Z",
      "location_count": 3,
      "location_summary": "Davis, California • Stanford, California • Grand Rapids, Michigan",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Grand Rapids",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01423201"
    },
    {
      "nct_id": "NCT03302494",
      "title": "WAveCrest Vs. Watchman TranssEptal LAA Closure to REduce AF-Mediated STroke 2",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Stroke"
      ],
      "interventions": [
        {
          "name": "Coherex WaveCrest® Left Atrial Appendage Occlusion System",
          "type": "DEVICE"
        },
        {
          "name": "Watchman® LAA Closure Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Coherex Medical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 248,
      "start_date": "2017-12-27",
      "completion_date": "2023-12-21",
      "has_results": true,
      "last_update_posted_date": "2025-03-12",
      "last_synced_at": "2026-06-26T11:18:10.848Z",
      "location_count": 23,
      "location_summary": "Birmingham, Alabama • Chandler, Arizona • Los Angeles, California + 18 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03302494"
    }
  ]
}