{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Brain+Lesions",
    "query": {
      "condition": "Brain Lesions"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 131,
    "total_pages": 14,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Brain+Lesions&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T13:51:54.555Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03669042",
      "title": "Post-market, Prospective Evaluation of PHOTO-oxidized Bovine Pericardium in Vascular Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Vascular Diseases",
        "Peripheral Arterial Disease",
        "Hemodialysis Access Failure (Disorder)",
        "Carotid Artery Diseases",
        "Abdominal Aortic Aneurism"
      ],
      "interventions": [
        {
          "name": "PhotoFix",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Artivion Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 94,
      "start_date": "2018-11-20",
      "completion_date": "2020-07-10",
      "has_results": true,
      "last_update_posted_date": "2024-10-08",
      "last_synced_at": "2026-07-22T13:51:54.555Z",
      "location_count": 9,
      "location_summary": "Tucson, Arizona • Des Moines, Iowa • Boston, Massachusetts + 6 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Des Moines",
          "state": "Iowa"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03669042"
    },
    {
      "nct_id": "NCT00870779",
      "title": "Fluorescence Guided Resection of Brain Tumors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Brain Tumors"
      ],
      "interventions": [
        {
          "name": "5-aminolevulinic acid",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "David W. Roberts",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 105,
      "start_date": "2007-05",
      "completion_date": "2013-07-02",
      "has_results": false,
      "last_update_posted_date": "2019-06-14",
      "last_synced_at": "2026-07-22T13:51:54.555Z",
      "location_count": 1,
      "location_summary": "Lebanon, New Hampshire",
      "locations": [
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00870779"
    },
    {
      "nct_id": "NCT06299891",
      "title": "Efficacy and Safety of Phentermine/Topiramate in Youth With Hypothalamic Obesity",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Hypothalamic Obesity",
        "Hypothalamic Tumor",
        "Craniopharyngioma"
      ],
      "interventions": [
        {
          "name": "Phentermine / Topiramate Extended Release Oral Capsule [Qsymia]",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Seattle Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "28 Years",
        "sex": "ALL",
        "summary": "6 Years to 28 Years"
      },
      "enrollment_count": 24,
      "start_date": "2025-03-01",
      "completion_date": "2026-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-28",
      "last_synced_at": "2026-07-22T13:51:54.555Z",
      "location_count": 2,
      "location_summary": "Philadelphia, Pennsylvania • Seattle, Washington",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06299891"
    },
    {
      "nct_id": "NCT02729740",
      "title": "Assessment of the Embolization of Neurovascular Lesions Using the Penumbra Smart Coil",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intracranial Aneurysm"
      ],
      "interventions": [
        {
          "name": "Penumbra Smart Coil",
          "type": "DEVICE"
        },
        {
          "name": "Penumbra Coil 400TM (PC400), Penumbra Occlusion DeviceTM(POD)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Penumbra Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 995,
      "start_date": "2016-06-03",
      "completion_date": "2019-12-27",
      "has_results": true,
      "last_update_posted_date": "2021-03-01",
      "last_synced_at": "2026-07-22T13:51:54.555Z",
      "location_count": 71,
      "location_summary": "Dothan, Alabama • Mesa, Arizona • Phoenix, Arizona + 62 more",
      "locations": [
        {
          "city": "Dothan",
          "state": "Alabama"
        },
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02729740"
    },
    {
      "nct_id": "NCT07493447",
      "title": "Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Meningioma",
        "Glioblastoma",
        "Acoustic Neuroma",
        "Brain Cancer",
        "Pituitary Adenoma"
      ],
      "interventions": [
        {
          "name": "Panitumumab-IRDye800",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Eben Rosenthal",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2026-07",
      "completion_date": "2031-06",
      "has_results": false,
      "last_update_posted_date": "2026-06-30",
      "last_synced_at": "2026-07-22T13:51:54.555Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07493447"
    },
    {
      "nct_id": "NCT00024908",
      "title": "Test of A Model of Representational Knowledge Stored in the Human Prefrontal Cortex",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Intracranial Central Nervous System Disorder",
        "Mental Disorder",
        "Healthy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "6 Years to 90 Years"
      },
      "enrollment_count": 949,
      "start_date": "2001-10-01",
      "completion_date": "2010-04-07",
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-07-22T13:51:54.555Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00024908"
    },
    {
      "nct_id": "NCT00879658",
      "title": "Safety, Tolerability, Efficacy and Optimal Dose Finding Study of BAF312 in Patients With Relapsing-remitting Multiple Sclerosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Relapsing-remitting Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "BAF312",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novartis Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 297,
      "start_date": "2009-03-30",
      "completion_date": "2011-05-04",
      "has_results": true,
      "last_update_posted_date": "2020-01-13",
      "last_synced_at": "2026-07-22T13:51:54.555Z",
      "location_count": 16,
      "location_summary": "Cullman, Alabama • San Francisco, California • Centennial, Colorado + 13 more",
      "locations": [
        {
          "city": "Cullman",
          "state": "Alabama"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Centennial",
          "state": "Colorado"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Pompano Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00879658"
    },
    {
      "nct_id": "NCT05267587",
      "title": "Preop fSRS for Resectable Brain Metastases",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Brain Metastases",
        "Brain Lesion"
      ],
      "interventions": [
        {
          "name": "Hypofractionated Stereotactic Radiosurgery",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "RADIATION"
      ],
      "sponsor": "H. Lee Moffitt Cancer Center and Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 49,
      "start_date": "2022-03-11",
      "completion_date": "2026-08-21",
      "has_results": false,
      "last_update_posted_date": "2026-03-31",
      "last_synced_at": "2026-07-22T13:51:54.555Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05267587"
    },
    {
      "nct_id": "NCT00474292",
      "title": "Influence of Area of Brain Damage on Brain Reorganization After Chronic Stroke",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Central Nervous System Disease",
        "Cerebrovascular Accident",
        "Stroke"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 4,
      "start_date": "2007-05-14",
      "completion_date": "2011-04-08",
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-07-22T13:51:54.555Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00474292"
    },
    {
      "nct_id": "NCT04086524",
      "title": "A Patch Free Treatment for Young Children With Amblyopia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amblyopia",
        "Binocular Vision Disorder"
      ],
      "interventions": [
        {
          "name": "Binocular cartoon treatment at home",
          "type": "OTHER"
        },
        {
          "name": "Patching",
          "type": "OTHER"
        },
        {
          "name": "Binocular cartoon treatment in office",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Waterloo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "36 Months",
        "maximum_age": "83 Months",
        "sex": "ALL",
        "summary": "36 Months to 83 Months"
      },
      "enrollment_count": 34,
      "start_date": "2020-01-13",
      "completion_date": "2023-11-30",
      "has_results": false,
      "last_update_posted_date": "2024-03-12",
      "last_synced_at": "2026-07-22T13:51:54.555Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04086524"
    }
  ]
}