{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Brain+Neoplasms&page=12", "query": { "condition": "Brain Neoplasms", "page": 12 }, "page_size": 10 }, "pagination": { "page": 12, "page_size": 10, "total_count": 2422, "total_pages": 243, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Brain+Neoplasms&page=13&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Brain+Neoplasms&page=11&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-22T13:21:44.148Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04462419", "title": "18F-fluciclovine PET/MRI Imaging for the Detection of Tumor Recurrence After Radiation Injury to the Brain", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Metastatic Intracranial Malignant Neoplasm", "Recurrent Intracranial Neoplasm" ], "interventions": [ { "name": "Dynamic Contrast-Enhanced Magnetic Resonance Imaging with Positron Emission Tomography", "type": "RADIATION" }, { "name": "Fluciclovine F18", "type": "OTHER" } ], "intervention_types": [ "RADIATION", "OTHER" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 19, "start_date": "2020-08-18", "completion_date": "2024-11-13", "has_results": false, "last_update_posted_date": "2025-09-10", "last_synced_at": "2026-10-22T13:21:44.148Z", "location_count": 1, "location_summary": "Jacksonville, Florida", "locations": [ { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04462419" }, { "nct_id": "NCT04099797", "title": "C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Diffuse Intrinsic Pontine Glioma", "High Grade Glioma", "Embryonal Tumor", "Ependymal Tumor" ], "interventions": [ { "name": "C7R-GD2.CART cells (IV and ICV infusion)", "type": "GENETIC" } ], "intervention_types": [ "GENETIC" ], "sponsor": "Baylor College of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Months", "maximum_age": "25 Years", "sex": "ALL", "summary": "12 Months to 25 Years" }, "enrollment_count": 56, "start_date": "2020-02-03", "completion_date": "2041-02", "has_results": false, "last_update_posted_date": "2026-08-03", "last_synced_at": "2026-10-22T13:21:44.148Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04099797" }, { "nct_id": "NCT05660408", "title": "RNA Lipid Particles Targeting Pediatric Recurrent Intracranial Malignancies and Other systEmic Solid Tumors", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Recurrent Pulmonary Osteosarcoma", "Recurrent High-grade Glioma" ], "interventions": [ { "name": "pp65 RNA LP (DP1)", "type": "BIOLOGICAL" }, { "name": "pp65/tumor mRNA RNA-LP (DP2)", "type": "BIOLOGICAL" }, { "name": "Surgical Biopsy/Resection", "type": "PROCEDURE" } ], "intervention_types": [ "BIOLOGICAL", "PROCEDURE" ], "sponsor": "University of Florida", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "3 Years", "maximum_age": "39 Years", "sex": "ALL", "summary": "3 Years to 39 Years" }, "enrollment_count": 36, "start_date": "2025-03-12", "completion_date": "2035-10", "has_results": false, "last_update_posted_date": "2026-03-09", "last_synced_at": "2026-10-22T13:21:44.148Z", "location_count": 1, "location_summary": "Gainesville, Florida", "locations": [ { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05660408" }, { "nct_id": "NCT00626015", "title": "Chemotherapy, Radiation Therapy, and Vaccine Therapy With Basiliximab in Treating Patients With Glioblastoma Multiforme That Has Been Removed by Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Malignant Neoplasms of Brain" ], "interventions": [ { "name": "PEP-3-KLH conjugate vaccine", "type": "BIOLOGICAL" }, { "name": "daclizumab", "type": "BIOLOGICAL" }, { "name": "temozolomide", "type": "DRUG" }, { "name": "placebo", "type": "OTHER" }, { "name": "PEP-3-KLH", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL", "DRUG", "OTHER" ], "sponsor": "John Sampson", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "120 Years", "sex": "ALL", "summary": "18 Years to 120 Years" }, "enrollment_count": 16, "start_date": "2007-03", "completion_date": "2013-02", "has_results": false, "last_update_posted_date": "2016-01-21", "last_synced_at": "2026-10-22T13:21:44.148Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00626015" }, { "nct_id": "NCT00005976", "title": "Pyrazoloacridine Plus Carboplatin in Treating Patients With Recurrent Glioma", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Brain and Central Nervous System Tumors" ], "interventions": [ { "name": "carboplatin", "type": "DRUG" }, { "name": "pyrazoloacridine", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Cancer Institute (NCI)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2000-05", "completion_date": "2007-04", "has_results": false, "last_update_posted_date": "2013-06-03", "last_synced_at": "2026-10-22T13:21:44.148Z", "location_count": 22, "location_summary": "Scottsdale, Arizona • Jacksonville, Florida • Peoria, Illinois + 19 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Peoria", "state": "Illinois" }, { "city": "Urbana", "state": "Illinois" }, { "city": "Cedar Rapids", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT00005976" }, { "nct_id": "NCT05864274", "title": "Improve Cancer-related Cognitive Impairment", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Gynecologic Cancer", "Chemotherapy Effect", "Chemo-brain", "Cancer-related Cognitive Difficulties" ], "interventions": [ { "name": "Cognitive training application", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of Alabama at Birmingham", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "90 Years", "sex": "FEMALE", "summary": "18 Years to 90 Years · Female only" }, "enrollment_count": 64, "start_date": "2024-09-01", "completion_date": "2027-08-01", "has_results": false, "last_update_posted_date": "2025-11-24", "last_synced_at": "2026-10-22T13:21:44.148Z", "location_count": 1, "location_summary": "Birmingham, Alabama", "locations": [ { "city": "Birmingham", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT05864274" }, { "nct_id": "NCT07132190", "title": "Stereotactic Radiation for Growing/Changing Brain Metastases With Same-Day Radiation Planning and Treatment With Margin Reduction", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Brain Metastases, Adult", "Brain Tumor - Metastatic", "Brain Metastases From Non-small Cell Lung Cancer (NSCLC)", "Brain Metastases From Extra-cranial Solid Tumors" ], "interventions": [ { "name": "Linear accelerator-based stereotactic radiation for brain metastases using 0mm or 1mm PTV", "type": "RADIATION" } ], "intervention_types": [ "RADIATION" ], "sponsor": "Ayal A. Aizer, MD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2025-12-30", "completion_date": "2029-09", "has_results": false, "last_update_posted_date": "2026-09-08", "last_synced_at": "2026-10-22T13:21:44.148Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT07132190" }, { "nct_id": "NCT03364803", "title": "Collecting Information About Treatment Results for Patients With Cushing's Syndrome", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Cushing's Disease", "Cushing Syndrome", "Cushing Disease" ], "interventions": [ { "name": "Cushing's QoL (Quality of Life Questionnaire)", "type": "OTHER" }, { "name": "Nottingham Health Profile (NHP)", "type": "OTHER" }, { "name": "Hospital Anxiety and Depression Scale (HADS)", "type": "OTHER" }, { "name": "Perceived Stress Scale (PSS)", "type": "OTHER" }, { "name": "Barratt's Impulsivity Scale (BIS)", "type": "OTHER" }, { "name": "Beck Depression Inventory (BDI)", "type": "OTHER" }, { "name": "State-Trait Anxiety Inventory (STAI)", "type": "OTHER" }, { "name": "State Food Craving Questionnaire-State (FCQ-S)", "type": "OTHER" }, { "name": "Trait Food Craving Questionnaire-Trait (FCQ-T)", "type": "OTHER" }, { "name": "Visual Analogue Scale (VAS)", "type": "OTHER" }, { "name": "Sensitivity to Reinforcement of Addictive and other Primary Rewards (STRAP-R) food variant", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Memorial Sloan Kettering Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "14 Years", "maximum_age": null, "sex": "ALL", "summary": "14 Years and older" }, "enrollment_count": 300, "start_date": "2017-11-28", "completion_date": "2026-11-28", "has_results": false, "last_update_posted_date": "2025-10-23", "last_synced_at": "2026-10-22T13:21:44.148Z", "location_count": 7, "location_summary": "Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more", "locations": [ { "city": "Basking Ridge", "state": "New Jersey" }, { "city": "Middletown", "state": "New Jersey" }, { "city": "Montvale", "state": "New Jersey" }, { "city": "Commack", "state": "New York" }, { "city": "Harrison", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT03364803" }, { "nct_id": "NCT00437060", "title": "Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Childhood B Acute Lymphoblastic Leukemia", "Childhood T Acute Lymphoblastic Leukemia", "Cognitive Side Effects of Cancer Therapy", "Long-Term Effects Secondary to Cancer Therapy in Children", "Neurotoxicity Syndrome", "Psychological Impact of Cancer", "Untreated Childhood Acute Lymphoblastic Leukemia" ], "interventions": [ { "name": "Cognitive Assessment", "type": "PROCEDURE" }, { "name": "Diffusion Tensor Imaging", "type": "PROCEDURE" }, { "name": "Laboratory Biomarker Analysis", "type": "OTHER" }, { "name": "Pharmacological Study", "type": "OTHER" }, { "name": "Psychosocial Assessment and Care", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE", "OTHER" ], "sponsor": "Children's Oncology Group", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "17 Years", "sex": "ALL", "summary": "1 Year to 17 Years" }, "enrollment_count": 233, "start_date": "2007-01", "completion_date": null, "has_results": false, "last_update_posted_date": "2017-07-21", "last_synced_at": "2026-10-22T13:21:44.148Z", "location_count": 102, "location_summary": "Birmingham, Alabama • Downey, California • Long Beach, California + 83 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Birmingham", "state": "Alabama" }, { "city": "Downey", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00437060" }, { "nct_id": "NCT04209023", "title": "The Use of Navigated Transcranial Magnetic Stimulation (nTMS) in the Inhibition of Neurofunctional Regions of Interest", "overall_status": "SUSPENDED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Brain Tumor", "Surgery" ], "interventions": [ { "name": "Transcranial Magnetic Stimulation", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Neurological Associates of West Los Angeles", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 10, "start_date": "2023-12-16", "completion_date": "2025-06-18", "has_results": false, "last_update_posted_date": "2022-09-28", "last_synced_at": "2026-10-22T13:21:44.148Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04209023" } ] }