{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Breathlessness&page=2",
    "query": {
      "condition": "Breathlessness",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Breathlessness&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T04:53:10.629Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06149429",
      "title": "Virtual Reality at End-of-life",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "End of Life",
        "Pain",
        "Nausea",
        "Fatigue",
        "Well-Being, Psychological",
        "Depression",
        "Dyspnea",
        "Appetite Loss",
        "Anxiety"
      ],
      "interventions": [
        {
          "name": "Personalized virtual reality experience",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "State University of New York at Buffalo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 9,
      "start_date": "2023-10-23",
      "completion_date": "2024-07-15",
      "has_results": false,
      "last_update_posted_date": "2024-12-19",
      "last_synced_at": "2026-06-11T04:53:10.629Z",
      "location_count": 1,
      "location_summary": "Cheektowaga, New York",
      "locations": [
        {
          "city": "Cheektowaga",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06149429"
    },
    {
      "nct_id": "NCT06038630",
      "title": "129Xe MRI Cardiopulmonary",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Interstitial Lung Disease",
        "Chronic Thromboembolic Pulmonary Hypertension",
        "Acute Pulmonary Embolism",
        "Anemia",
        "Polycythemia",
        "Dyspnea"
      ],
      "interventions": [
        {
          "name": "Hyperpolarized Xe129",
          "type": "DRUG"
        },
        {
          "name": "Oxygen Administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Bastiaan Driehuys",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 125,
      "start_date": "2024-01-12",
      "completion_date": "2028-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-04",
      "last_synced_at": "2026-06-11T04:53:10.629Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06038630"
    },
    {
      "nct_id": "NCT01461681",
      "title": "Improving Care of Patients With Heart Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression",
        "Pain",
        "Dyspnea",
        "Quality of Life"
      ],
      "interventions": [
        {
          "name": "Symptom Management Service for Heart failure",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2012-03",
      "completion_date": "2013-12",
      "has_results": false,
      "last_update_posted_date": "2014-05-14",
      "last_synced_at": "2026-06-11T04:53:10.629Z",
      "location_count": 2,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01461681"
    },
    {
      "nct_id": "NCT05770518",
      "title": "Biofeedback vs Laryngeal Control Therapy in Management of Paradoxical Vocal Fold Motion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Paradoxical Vocal Fold Motion",
        "Vocal Cord Dysfunction"
      ],
      "interventions": [
        {
          "name": "Biofeedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Laryngeal control therapy (LCT)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 51,
      "start_date": "2023-03-07",
      "completion_date": "2024-07-30",
      "has_results": false,
      "last_update_posted_date": "2025-12-22",
      "last_synced_at": "2026-06-11T04:53:10.629Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05770518"
    },
    {
      "nct_id": "NCT02114944",
      "title": "Treatment of Dyspnea in Do-not-intubate Patients",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Respiratory Failure",
        "Acute on Chronic Respiratory Failure",
        "Dyspnea"
      ],
      "interventions": [
        {
          "name": "NIV",
          "type": "DEVICE"
        },
        {
          "name": "CPAP",
          "type": "DEVICE"
        },
        {
          "name": "Standard oxygen",
          "type": "DEVICE"
        },
        {
          "name": "HFNC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Tufts Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 400,
      "start_date": "2014-04",
      "completion_date": "2023-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-05-13",
      "last_synced_at": "2026-06-11T04:53:10.629Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02114944"
    },
    {
      "nct_id": "NCT03653104",
      "title": "Melodica Orchestra for Dyspnea: Safety and Feasibility Pilot",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "COPD",
        "Chronic Obstructive Pulmonary Disease",
        "Dyspnea",
        "Breathlessness",
        "Emphysema",
        "Chronic Bronchitis"
      ],
      "interventions": [
        {
          "name": "Melodica Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pulmonary Health Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "VA Quality Enhancement Research Intiative",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2018-06-12",
      "completion_date": "2019-12-31",
      "has_results": false,
      "last_update_posted_date": "2021-03-15",
      "last_synced_at": "2026-06-11T04:53:10.629Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03653104"
    },
    {
      "nct_id": "NCT00586833",
      "title": "Heart Failure and a Preserved Ejection Fraction",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "O2 consumption max bike test",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 51,
      "start_date": "2007-04",
      "completion_date": "2009-06",
      "has_results": false,
      "last_update_posted_date": "2010-10-14",
      "last_synced_at": "2026-06-11T04:53:10.629Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00586833"
    },
    {
      "nct_id": "NCT00458419",
      "title": "Role of Endorphins in the Perception of Dyspnea in Patients With Chronic Obstructive Pulmonary Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Obstructive Pulmonary Disease"
      ],
      "interventions": [
        {
          "name": "naloxone versus placebo",
          "type": "DRUG"
        },
        {
          "name": "intravenous injection of normal saline or naloxone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Dartmouth-Hitchcock Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "50 Years to 90 Years"
      },
      "enrollment_count": 17,
      "start_date": "2005-09",
      "completion_date": "2007-05",
      "has_results": false,
      "last_update_posted_date": "2007-11-02",
      "last_synced_at": "2026-06-11T04:53:10.629Z",
      "location_count": 1,
      "location_summary": "Lebanon, New Hampshire",
      "locations": [
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00458419"
    },
    {
      "nct_id": "NCT07128511",
      "title": "Training Strategies to Maintain Performance",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Shortness of Breath",
        "Shortness of Breath/Dyspnea",
        "Respiratory Distress"
      ],
      "interventions": [
        {
          "name": "Multiple Inhalation Breathing Pattern",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tactical Breathing Technique",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 15,
      "start_date": "2025-08",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2025-08-19",
      "last_synced_at": "2026-06-11T04:53:10.629Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07128511"
    },
    {
      "nct_id": "NCT04397796",
      "title": "Study of the Safety of Therapeutic Tx With Immunomodulatory MSC in Adults With COVID-19 Infection Requiring Mechanical Ventilation",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "COVID"
      ],
      "interventions": [
        {
          "name": "BM-Allo.MSC",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "ImmunityBio, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 4,
      "start_date": "2020-08-03",
      "completion_date": "2020-09-06",
      "has_results": true,
      "last_update_posted_date": "2024-09-05",
      "last_synced_at": "2026-06-11T04:53:10.629Z",
      "location_count": 1,
      "location_summary": "Lynwood, California",
      "locations": [
        {
          "city": "Lynwood",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04397796"
    }
  ]
}