{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=CCSVI",
    "query": {
      "condition": "CCSVI"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 7,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T04:13:13.266Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01205633",
      "title": "Multi-center Registry for CCSVI Testing and Treatment",
      "overall_status": "SUSPENDED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "CCSVI",
        "Chronic Cerebrospinal Venous Insufficiency",
        "Venous Malformations of CNS Draining Veins"
      ],
      "interventions": [
        {
          "name": "venous angioplasty",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Hubbard Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 1000,
      "start_date": "2010-09",
      "completion_date": "2015-09",
      "has_results": false,
      "last_update_posted_date": "2012-09-18",
      "last_synced_at": "2026-07-24T04:13:13.266Z",
      "location_count": 9,
      "location_summary": "Downey, California • Oceanside, California • Atlanta, Georgia + 6 more",
      "locations": [
        {
          "city": "Downey",
          "state": "California"
        },
        {
          "city": "Oceanside",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Poughkeepsie",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01205633"
    },
    {
      "nct_id": "NCT01593891",
      "title": "Radiographic and Intravascular (IVUS) Evaluation of Venous Morphology During CCSVI Treatment",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "To Determine the Safety and Validity of Venous Angioplasty and",
        "Valvuloplasty in the Treatment of CCSVI. In Addition, it Will",
        "Allow Researchers to Sub-classify Valve Morphology in Relation",
        "to Treatment Success. This Will be Evidenced by Venous Patency",
        "Forty-eight Hours by Doppler Ultrasound as Well as Clinical",
        "Symptom Improvement."
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Synergy Health Concepts, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "20 Years to 60 Years"
      },
      "enrollment_count": 45,
      "start_date": "2011-08",
      "completion_date": "2012-09",
      "has_results": false,
      "last_update_posted_date": "2012-05-08",
      "last_synced_at": "2026-07-24T04:13:13.266Z",
      "location_count": 1,
      "location_summary": "Newport Beach, California",
      "locations": [
        {
          "city": "Newport Beach",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01593891"
    },
    {
      "nct_id": "NCT01201707",
      "title": "Evaluation of Angioplasty in the Treatment of Chronic Cerebrospinal Venous Insufficiency (CCSVI) in Multiple Sclerosis",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "Angioplasty",
          "type": "PROCEDURE"
        },
        {
          "name": "Observation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Community Care Physicians, P.C.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 18,
      "start_date": "2010-08",
      "completion_date": "2013-09",
      "has_results": false,
      "last_update_posted_date": "2013-11-26",
      "last_synced_at": "2026-07-24T04:13:13.266Z",
      "location_count": 2,
      "location_summary": "Albany, New York • Latham, New York",
      "locations": [
        {
          "city": "Albany",
          "state": "New York"
        },
        {
          "city": "Latham",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01201707"
    },
    {
      "nct_id": "NCT01089686",
      "title": "Study To Evaluate Treating Chronic Cerebrospinal Venous Insufficiency (CCSVI) in Multiple Sclerosis Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "Venoplasty",
          "type": "PROCEDURE"
        },
        {
          "name": "Sham procedure (non-treatment)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Manish Mehta, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 2,
      "start_date": "2010-08",
      "completion_date": "2012-10",
      "has_results": false,
      "last_update_posted_date": "2012-03-07",
      "last_synced_at": "2026-07-24T04:13:13.266Z",
      "location_count": 1,
      "location_summary": "Albany, New York",
      "locations": [
        {
          "city": "Albany",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01089686"
    },
    {
      "nct_id": "NCT01593904",
      "title": "Venous Irregularities, Flow and Perfusion in MS Study",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Venous Irregularities, Flow and Perfusion in MS and Non-MS Participants"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Synergy Health Concepts, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "20 Years to 65 Years"
      },
      "enrollment_count": 400,
      "start_date": "2012-01",
      "completion_date": "2013-01",
      "has_results": false,
      "last_update_posted_date": "2012-05-08",
      "last_synced_at": "2026-07-24T04:13:13.266Z",
      "location_count": 1,
      "location_summary": "Newport Beach, California",
      "locations": [
        {
          "city": "Newport Beach",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01593904"
    },
    {
      "nct_id": "NCT01593358",
      "title": "Venous Obstruction in Neurodegenerative Disorders Research Registry",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Cerebral Spinal Venous Insufficiency"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Synergy Health Concepts, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 2000,
      "start_date": "2011-08",
      "completion_date": "2014-01",
      "has_results": false,
      "last_update_posted_date": "2012-05-08",
      "last_synced_at": "2026-07-24T04:13:13.266Z",
      "location_count": 1,
      "location_summary": "Newport Beach, California",
      "locations": [
        {
          "city": "Newport Beach",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01593358"
    },
    {
      "nct_id": "NCT01356134",
      "title": "Vascular Fundus Changes in Patients With High Probability of Chronic Cerebrospinal Venous Insufficiency (CCSVI)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ehlers-Danlos Syndrome",
        "Multiple Sclerosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Genetic Disease Investigators",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 60,
      "start_date": "2011-05",
      "completion_date": "2015-04",
      "has_results": false,
      "last_update_posted_date": "2015-04-03",
      "last_synced_at": "2026-07-24T04:13:13.266Z",
      "location_count": 1,
      "location_summary": "Colleyville, Texas",
      "locations": [
        {
          "city": "Colleyville",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01356134"
    }
  ]
}