{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=CIS&page=6", "query": { "condition": "CIS", "page": 6 }, "page_size": 10 }, "pagination": { "page": 6, "page_size": 10, "total_count": 449, "total_pages": 45, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=CIS&page=7&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=CIS&page=5&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-31T03:00:46.768Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01819233", "title": "Caloric Restriction in Treating Patients With Stage 0-I Breast Cancer Undergoing Surgery and Radiation Therapy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Ductal Breast Carcinoma in Situ", "Invasive Ductal Breast Carcinoma", "Invasive Lobular Breast Carcinoma", "Lobular Breast Carcinoma in Situ", "Recurrent Breast Cancer", "Stage IA Breast Cancer", "Stage IB Breast Cancer" ], "interventions": [ { "name": "Behavioral dietary intervention", "type": "BEHAVIORAL" }, { "name": "Therapeutic conventional surgery", "type": "PROCEDURE" }, { "name": "Radiation therapy", "type": "RADIATION" }, { "name": "Counseling intervention", "type": "OTHER" }, { "name": "Quality-of-life assessment", "type": "PROCEDURE" } ], "intervention_types": [ "BEHAVIORAL", "PROCEDURE", "RADIATION", "OTHER" ], "sponsor": "Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 38, "start_date": "2013-03-08", "completion_date": "2019-09", "has_results": true, "last_update_posted_date": "2025-06-06", "last_synced_at": "2026-10-31T03:00:46.768Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT01819233" }, { "nct_id": "NCT00725985", "title": "Oral Cladribine in Early Multiple Sclerosis (MS)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Multiple Sclerosis" ], "interventions": [ { "name": "Cladribine", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Rebif® new formulation (RNF)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "EMD Serono Research & Development Institute, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 617, "start_date": "2008-12-31", "completion_date": "2012-04-30", "has_results": true, "last_update_posted_date": "2021-03-22", "last_synced_at": "2026-10-31T03:00:46.768Z", "location_count": 24, "location_summary": "Phoenix, Arizona • Newport Beach, California • Denver, Colorado + 21 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Newport Beach", "state": "California" }, { "city": "Denver", "state": "Colorado" }, { "city": "Fort Collins", "state": "Colorado" }, { "city": "Melbourne", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00725985" }, { "nct_id": "NCT03964415", "title": "A Study of Heterologous Vaccine Regimen of Adenovirus Serotype 26 Mosaic4 Human Immunodeficiency Virus(Ad26.Mos4.HIV), Adjuvanted Clade C gp140 and Mosaic gp140 to Prevent HIV-1 Infection Among Cis-gender Men and Transgender Individuals Who Have Sex With Cis-gender Men and/or Transgender Individuals", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "Ad26.Mos4.HIV", "type": "BIOLOGICAL" }, { "name": "Clade C and Mosaic gp140 HIV bivalent vaccine", "type": "BIOLOGICAL" }, { "name": "Placebo", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Janssen Vaccines & Prevention B.V.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 3900, "start_date": "2019-10-31", "completion_date": "2023-08-10", "has_results": true, "last_update_posted_date": "2024-07-31", "last_synced_at": "2026-10-31T03:00:46.768Z", "location_count": 20, "location_summary": "Birmingham, Alabama • San Francisco, California • Washington D.C., District of Columbia + 14 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "San Francisco", "state": "California" }, { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Miami", "state": "Florida" }, { "city": "Orlando", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03964415" }, { "nct_id": "NCT01753908", "title": "Broccoli Sprout Extract in Treating Patients With Breast Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Ductal Breast Carcinoma", "Ductal Breast Carcinoma In Situ", "Estrogen Receptor Negative", "Estrogen Receptor Positive", "Invasive Breast Carcinoma", "Lobular Breast Carcinoma", "Postmenopausal", "Stage IA Breast Cancer", "Stage IB Breast Cancer", "Stage IIA Breast Cancer", "Stage IIB Breast Cancer" ], "interventions": [ { "name": "Broccoli Sprout Extract", "type": "DRUG" }, { "name": "Laboratory Biomarker Analysis", "type": "OTHER" }, { "name": "Pharmacological Study", "type": "OTHER" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Roswell Park Cancer Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "FEMALE", "summary": "21 Years and older · Female only" }, "enrollment_count": 30, "start_date": "2013-05-21", "completion_date": "2018-08-23", "has_results": false, "last_update_posted_date": "2019-10-31", "last_synced_at": "2026-10-31T03:00:46.768Z", "location_count": 1, "location_summary": "Buffalo, New York", "locations": [ { "city": "Buffalo", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01753908" }, { "nct_id": "NCT03535506", "title": "Preoperative Palbociclib in Patients With DCIS of the Breast That Are Candidates for Surgery", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "DCIS" ], "interventions": [ { "name": "Palbociclib", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Georgetown University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 17, "start_date": "2018-10-08", "completion_date": "2023-12-06", "has_results": true, "last_update_posted_date": "2025-09-26", "last_synced_at": "2026-10-31T03:00:46.768Z", "location_count": 2, "location_summary": "Washington D.C., District of Columbia", "locations": [ { "city": "Washington D.C.", "state": "District of Columbia" }, { "city": "Washington D.C.", "state": "District of Columbia" } ], "official_url": "https://clinicaltrials.gov/study/NCT03535506" }, { "nct_id": "NCT02352883", "title": "MRI and Gene Expression in Diagnosing Patients With Ductal Breast Cancer In Situ", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Ductal Breast Carcinoma In Situ" ], "interventions": [ { "name": "Magnetic Resonance Imaging", "type": "PROCEDURE" }, { "name": "Therapeutic Conventional Surgery", "type": "PROCEDURE" }, { "name": "Therapeutic Surgical Procedure", "type": "PROCEDURE" }, { "name": "Radiation Therapy", "type": "RADIATION" }, { "name": "Endocrine Therapy", "type": "DRUG" }, { "name": "Quality-of-Life Assessment", "type": "OTHER" }, { "name": "Laboratory Biomarker Analysis", "type": "OTHER" }, { "name": "Cytology Specimen Collection Procedure", "type": "OTHER" } ], "intervention_types": [ "PROCEDURE", "RADIATION", "DRUG", "OTHER" ], "sponsor": "ECOG-ACRIN Cancer Research Group", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 368, "start_date": "2015-03-25", "completion_date": "2027-11", "has_results": false, "last_update_posted_date": "2025-12-19", "last_synced_at": "2026-10-31T03:00:46.768Z", "location_count": 76, "location_summary": "San Diego, California • San Marcos, California • Greenwich, Connecticut + 56 more", "locations": [ { "city": "San Diego", "state": "California" }, { "city": "San Marcos", "state": "California" }, { "city": "Greenwich", "state": "Connecticut" }, { "city": "Hartford", "state": "Connecticut" }, { "city": "Meriden", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT02352883" }, { "nct_id": "NCT01023477", "title": "Study of the Efficacy of Chloroquine in the Treatment of Ductal Carcinoma in Situ (The PINC Trial)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Carcinoma, Intraductal, Noninfiltrating", "DCIS", "Ductal Carcinoma In Situ" ], "interventions": [ { "name": "Chloroquine Standard Dose (500mg/week)", "type": "DRUG" }, { "name": "Chloroquine Low Dose (250mg/week)", "type": "DRUG" }, { "name": "Breast Biopsy", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Inova Health Care Services", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 12, "start_date": "2009-12", "completion_date": "2016-10", "has_results": true, "last_update_posted_date": "2021-06-29", "last_synced_at": "2026-10-31T03:00:46.768Z", "location_count": 4, "location_summary": "Fairfax, Virginia • Falls Church, Virginia", "locations": [ { "city": "Fairfax", "state": "Virginia" }, { "city": "Fairfax", "state": "Virginia" }, { "city": "Fairfax", "state": "Virginia" }, { "city": "Falls Church", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT01023477" }, { "nct_id": "NCT04535323", "title": "Platelet Rich Plasma for the Treatment of Genitourinary Syndrome of Menopause in Patients With Stage 0-III Breast Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Anatomic Stage 0 Breast Cancer AJCC v8", "Anatomic Stage I Breast Cancer AJCC v8", "Anatomic Stage IA Breast Cancer AJCC v8", "Anatomic Stage IB Breast Cancer AJCC v8", "Anatomic Stage II Breast Cancer AJCC v8", "Anatomic Stage IIA Breast Cancer AJCC v8", "Anatomic Stage IIB Breast Cancer AJCC v8", "Anatomic Stage III Breast Cancer AJCC v8", "Anatomic Stage IIIA Breast Cancer AJCC v8", "Anatomic Stage IIIB Breast Cancer AJCC v8", "Anatomic Stage IIIC Breast Cancer AJCC v8", "Breast Adenocarcinoma", "Genitourinary Syndrome of Menopause", "Prognostic Stage 0 Breast Cancer AJCC v8", "Prognostic Stage I Breast Cancer AJCC v8", "Prognostic Stage IA Breast Cancer AJCC v8", "Prognostic Stage IB Breast Cancer AJCC v8", "Prognostic Stage II Breast Cancer AJCC v8", "Prognostic Stage IIA Breast Cancer AJCC v8", "Prognostic Stage IIB Breast Cancer AJCC v8", "Prognostic Stage III Breast Cancer AJCC v8", "Prognostic Stage IIIA Breast Cancer AJCC v8", "Prognostic Stage IIIB Breast Cancer AJCC v8", "Prognostic Stage IIIC Breast Cancer AJCC v8" ], "interventions": [ { "name": "Quality-of-Life Assessment", "type": "OTHER" }, { "name": "Questionnaire Administration", "type": "OTHER" }, { "name": "Therapeutic Autologous Platelet-rich Plasma", "type": "BIOLOGICAL" } ], "intervention_types": [ "OTHER", "BIOLOGICAL" ], "sponsor": "Mayo Clinic", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "FEMALE", "summary": "18 Years and older · Female only" }, "enrollment_count": 20, "start_date": "2020-09-23", "completion_date": "2024-01-10", "has_results": false, "last_update_posted_date": "2024-04-03", "last_synced_at": "2026-10-31T03:00:46.768Z", "location_count": 1, "location_summary": "Jacksonville, Florida", "locations": [ { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT04535323" }, { "nct_id": "NCT03345420", "title": "Hypofractionated Radiation Therapy in Treating Patients With Stage 0-IIB Breast Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Ductal Breast Carcinoma In Situ", "Invasive Breast Carcinoma", "Stage 0 Breast Cancer", "Stage I Breast Cancer", "Stage IA Breast Cancer", "Stage IB Breast Cancer", "Stage II Breast Cancer", "Stage IIA Breast Cancer", "Stage IIB Breast Cancer" ], "interventions": [ { "name": "Hypofractionated Radiation Therapy", "type": "RADIATION" } ], "intervention_types": [ "RADIATION" ], "sponsor": "University of Utah", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 102, "start_date": "2017-12-12", "completion_date": "2025-06-26", "has_results": true, "last_update_posted_date": "2025-12-30", "last_synced_at": "2026-10-31T03:00:46.768Z", "location_count": 1, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT03345420" }, { "nct_id": "NCT01668823", "title": "Photodynamic Therapy in Treating Patients With Lung Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Adenocarcinoma of the Lung", "Large Cell Lung Cancer", "Recurrent Non-small Cell Lung Cancer", "Squamous Cell Lung Cancer", "Stage 0 Non-small Cell Lung Cancer" ], "interventions": [ { "name": "HPPH", "type": "DRUG" }, { "name": "photodynamic therapy", "type": "DRUG" }, { "name": "therapeutic bronchoscopy", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Roswell Park Cancer Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 17, "start_date": "2004-02", "completion_date": "2014-06", "has_results": false, "last_update_posted_date": "2014-07-31", "last_synced_at": "2026-10-31T03:00:46.768Z", "location_count": 1, "location_summary": "Buffalo, New York", "locations": [ { "city": "Buffalo", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01668823" } ] }