{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=CLN3&page=2", "query": { "condition": "CLN3", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=CLN3&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-07-22T22:35:14.660Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01907087", "title": "A Phase 1/2 Open-Label Dose-Escalation Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of Intracerebroventricular BMN 190 in Patients With Late-Infantile Neuronal Ceroid Lipofuscinosis (CLN2) Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Jansky-Bielschowsky Disease", "Batten Disease", "Late-Infantile Neuronal Ceroid Lipofuscinosis Type 2", "CLN2 Disease" ], "interventions": [ { "name": "BMN 190", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "BioMarin Pharmaceutical", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "3 Years", "maximum_age": "15 Years", "sex": "ALL", "summary": "3 Years to 15 Years" }, "enrollment_count": 24, "start_date": "2013-09", "completion_date": "2015-11", "has_results": true, "last_update_posted_date": "2019-03-08", "last_synced_at": "2026-07-22T22:35:14.660Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01907087" }, { "nct_id": "NCT07582484", "title": "Gene Therapy Trial for CLN6 Batten Disease", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "CLN6", "Batten Disease", "Batten's Disease", "Neuronal Ceroid Lipofuscinosis CLN6", "Neuronal Ceroid Lipofuscinosis" ], "interventions": [ { "name": "scAAV9.CB.CLN6 (dose: 1.5E14 vector genomes)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "The Charlotte and Gwenyth Gray Foundation", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "4 Months", "maximum_age": null, "sex": "ALL", "summary": "4 Months and older" }, "enrollment_count": 12, "start_date": "2026-08", "completion_date": "2028-08", "has_results": false, "last_update_posted_date": "2026-05-14", "last_synced_at": "2026-07-22T22:35:14.660Z", "location_count": 1, "location_summary": "La Jolla, California", "locations": [ { "city": "La Jolla", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07582484" }, { "nct_id": "NCT03307304", "title": "Investigations of Juvenile Neuronal Ceroid Lipofuscinosis", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Juvenile Neuronal Ceroid Lipofuscinosis (CLN3)", "Batten Disease" ], "interventions": [], "intervention_types": [], "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Week", "maximum_age": "100 Years", "sex": "ALL", "summary": "1 Week to 100 Years" }, "enrollment_count": 300, "start_date": "2017-11-27", "completion_date": "2050-12-31", "has_results": false, "last_update_posted_date": "2026-02-24", "last_synced_at": "2026-07-22T22:35:14.660Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT03307304" }, { "nct_id": "NCT02485899", "title": "An Extension Study to Evaluate the Long-Term Efficacy and Safety of BMN 190 in Patients With CLN2 Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Jansky-Bielschowsky Disease", "Batten Disease", "Late-Infantile Neuronal Ceroid Lipofuscinosis Type 2", "CLN2 Disease", "CLN2 Disorder" ], "interventions": [ { "name": "BMN 190", "type": "BIOLOGICAL" }, { "name": "Intracerebroventricular (ICV) access device", "type": "DEVICE" } ], "intervention_types": [ "BIOLOGICAL", "DEVICE" ], "sponsor": "BioMarin Pharmaceutical", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "3 Years", "maximum_age": "16 Years", "sex": "ALL", "summary": "3 Years to 16 Years" }, "enrollment_count": 23, "start_date": "2015-02", "completion_date": "2020-12-10", "has_results": true, "last_update_posted_date": "2022-08-24", "last_synced_at": "2026-07-22T22:35:14.660Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT02485899" }, { "nct_id": "NCT02254863", "title": "UCB Transplant of Inherited Metabolic Diseases With Administration of Intrathecal UCB Derived Oligodendrocyte-Like Cells", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Adrenoleukodystrophy", "Batten Disease", "Mucopolysaccharidosis II", "Leukodystrophy, Globoid Cell", "Leukodystrophy, Metachromatic", "Neimann Pick Disease", "Pelizaeus-Merzbacher Disease", "Sandhoff Disease", "Tay-Sachs Disease", "Brain Diseases, Metabolic, Inborn", "Alpha-Mannosidosis", "Sanfilippo Mucopolysaccharidoses" ], "interventions": [ { "name": "DUOC-01", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Joanne Kurtzberg, MD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Week", "maximum_age": "22 Years", "sex": "ALL", "summary": "1 Week to 22 Years" }, "enrollment_count": 40, "start_date": "2014-09", "completion_date": "2026-10", "has_results": false, "last_update_posted_date": "2025-09-08", "last_synced_at": "2026-07-22T22:35:14.660Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02254863" }, { "nct_id": "NCT05007990", "title": "Caregiving Networks Across Disease Context and the Life Course", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Inherited Metabolic Disorders", "Undiagnosed Diseases", "Batten's Disease", "Tay Sachs", "Diabetes" ], "interventions": [], "intervention_types": [], "sponsor": "National Human Genome Research Institute (NHGRI)", "sponsor_class": "NIH", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 2800, "start_date": "2022-09-08", "completion_date": "2030-12-31", "has_results": false, "last_update_posted_date": "2026-07-14", "last_synced_at": "2026-07-22T22:35:14.660Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT05007990" }, { "nct_id": "NCT01399047", "title": "Cellcept for Treatment of Juvenile Neuronal Ceroid Lipofuscinosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Juvenile Neuronal Ceroid Lipofuscinosis" ], "interventions": [ { "name": "Mycophenolate mofetil", "type": "DRUG" }, { "name": "Liquid Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Rochester", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": "25 Years", "sex": "ALL", "summary": "6 Years to 25 Years" }, "enrollment_count": 19, "start_date": "2011-07", "completion_date": "2015-11", "has_results": true, "last_update_posted_date": "2019-05-21", "last_synced_at": "2026-07-22T22:35:14.660Z", "location_count": 1, "location_summary": "Rochester, New York", "locations": [ { "city": "Rochester", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT01399047" }, { "nct_id": "NCT06203106", "title": "NYSCF Scientific Discovery Biobank", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "ALS", "Amyotrophic Lateral Sclerosis", "Alzheimer Disease", "Alzheimer Disease, Early Onset", "Alzheimer Disease, Late Onset", "Batten Disease", "Corticobasal Degeneration", "Dementia", "Frontotemporal Dementia", "Huntington Disease", "Lewy Body Disease", "Multiple Sclerosis", "Multiple System Atrophy", "Parkinson Disease", "Parkinson's Disease and Parkinsonism", "Progressive Supranuclear Palsy", "INAD", "Diabetes", "Diabetes Mellitus", "Diabetes Mellitus, Type 2", "Diabetes Mellitus, Type 1", "Macular Degeneration", "Ovarian Cancer", "Cervical Cancer", "Uterine Cancer", "Vaginal Cancer", "Vulvar Cancer", "PTSD", "Post Traumatic Stress Disorder" ], "interventions": [ { "name": "Biological Sample Collection", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "New York Stem Cell Foundation Research Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Days", "maximum_age": null, "sex": "ALL", "summary": "30 Days and older" }, "enrollment_count": 10000, "start_date": "2022-11-10", "completion_date": "2045-11-10", "has_results": false, "last_update_posted_date": "2025-03-03", "last_synced_at": "2026-07-22T22:35:14.660Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT06203106" }, { "nct_id": "NCT04737460", "title": "Study for the Treatment for CLN7 Disease", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "CLN7" ], "interventions": [ { "name": "AAV9/CLN7", "type": "GENETIC" } ], "intervention_types": [ "GENETIC" ], "sponsor": "Benjamin Greenberg", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "18 Years", "sex": "ALL", "summary": "1 Year to 18 Years" }, "enrollment_count": 4, "start_date": "2021-05-04", "completion_date": "2029-02-01", "has_results": false, "last_update_posted_date": "2025-12-31", "last_synced_at": "2026-07-22T22:35:14.660Z", "location_count": 1, "location_summary": "Dallas, Texas", "locations": [ { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04737460" }, { "nct_id": "NCT03862274", "title": "Examining Developmental Outcomes of Children Diagnosed With CLN2 Disease", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Batten Disease", "CLN2", "Neuronal Ceroid-Lipofuscinoses" ], "interventions": [ { "name": "CLN2 Treatment", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Jessica Scherr", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 30, "start_date": "2018-12-01", "completion_date": "2025-12", "has_results": false, "last_update_posted_date": "2025-10-24", "last_synced_at": "2026-07-22T22:35:14.660Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT03862274" } ] }