{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=CNS+Progression&page=2", "query": { "condition": "CNS Progression", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=CNS+Progression&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-07-22T12:43:42.473Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00606918", "title": "Validation of a New Device to Measure Neuromuscular Disease Progression", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Amyotrophic Lateral Sclerosis & Other Neuromuscular Disorders" ], "interventions": [], "intervention_types": [], "sponsor": "Massachusetts General Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 120, "start_date": "2008-01", "completion_date": "2010-09", "has_results": false, "last_update_posted_date": "2011-05-12", "last_synced_at": "2026-07-22T12:43:42.473Z", "location_count": 1, "location_summary": "Charlestown, Massachusetts", "locations": [ { "city": "Charlestown", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00606918" }, { "nct_id": "NCT04028479", "title": "The Registry of Oncology Outcomes Associated With Testing and Treatment", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Adenocarcinoma", "Adenocystic Carcinoma", "Anal Cancer", "Appendix Cancer", "Brain Tumor", "Glioblastoma", "Astrocytoma", "Bile Duct Cancer", "Cholangiocarcinoma", "Bladder Cancer", "Bone Cancer", "Synovial Sarcoma", "Chondrosarcoma", "Liposarcoma", "Sarcoma, Kaposi", "Sarcoma,Soft Tissue", "Sarcoma", "Osteosarcoma", "CNS Cancer", "Brain Stem Neoplasms", "Breast Cancer", "Cervical Cancer", "Colorectal Cancer", "Rectal Cancer", "Colon Cancer", "Esophageal Cancer", "Esophagus Cancer", "Cancer of Colon", "Pancreatic Cancer", "Cancer of Pancreas", "Testis Cancer", "Testicular Cancer", "Ureter Cancer", "Renal Cell Carcinoma", "Kidney Cancer", "Gestational Trophoblastic Tumor", "Head and Neck Neoplasms", "Parotid Tumor", "Larynx Cancer", "Tongue Cancer", "Pharynx Cancer", "Salivary Gland Cancer", "Acute Myeloid Leukemia", "Chronic Myeloid Leukemia", "Acute Lymphoblastic Leukemia", "Multiple Myeloma", "Non Hodgkin Lymphoma", "Carcinoid Tumor", "Lung Cancer", "Neuroendocrine Tumors", "Mesothelioma", "Thyroid Cancer", "Parathyroid Neoplasms", "Adrenal Cancer", "Small Bowel Cancer", "Stomach Cancer", "Liver Cancer", "Hepatic Cancer", "Melanoma", "Skin Cancer", "Unknown Primary Tumors", "Uterine Cancer", "Fallopian Tube Cancer", "Ovarian Cancer", "Prostate Cancer", "Vaginal Cancer", "Penile Cancer", "Vulvar Cancer", "Waldenstrom Macroglobulinemia", "Cancer, Advanced", "Thymus Cancer", "Nasopharyngeal Carcinoma", "Multiple Endocrine Neoplasia", "Pheochromocytoma", "Small Cell Carcinoma", "Pulmonary Carcinoma" ], "interventions": [ { "name": "Biomarker Testing (L)", "type": "DIAGNOSTIC_TEST" }, { "name": "Systemic Treatment (T)", "type": "DRUG" }, { "name": "Patient Reported Outcomes (P)", "type": "OTHER" } ], "intervention_types": [ "DIAGNOSTIC_TEST", "DRUG", "OTHER" ], "sponsor": "Taproot Health", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 167, "start_date": "2021-05-05", "completion_date": "2024-10-31", "has_results": false, "last_update_posted_date": "2024-12-18", "last_synced_at": "2026-07-22T12:43:42.473Z", "location_count": 2, "location_summary": "Idaho Falls, Idaho • Laredo, Texas", "locations": [ { "city": "Idaho Falls", "state": "Idaho" }, { "city": "Laredo", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04028479" }, { "nct_id": "NCT03930173", "title": "18F-Fluciclovine PET to Distinguish Tumor Progression From Radiation Necrosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Secondary Malignant Neoplasm of Brain and Cerebral Meninges" ], "interventions": [ { "name": "18F-fluciclovine", "type": "DRUG" }, { "name": "PET/CT of the brain", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Case Comprehensive Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 18, "start_date": "2019-07-02", "completion_date": "2021-03-01", "has_results": false, "last_update_posted_date": "2021-05-05", "last_synced_at": "2026-07-22T12:43:42.473Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT03930173" }, { "nct_id": "NCT03205956", "title": "Measuring Parkinson's Disease Progression", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Parkinson's Disease" ], "interventions": [ { "name": "Levodopa", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Kevin J. Black, MD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "79 Years", "sex": "ALL", "summary": "40 Years to 79 Years" }, "enrollment_count": 31, "start_date": "2017-10-19", "completion_date": "2019-10-19", "has_results": false, "last_update_posted_date": "2022-10-14", "last_synced_at": "2026-07-22T12:43:42.473Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT03205956" }, { "nct_id": "NCT00147251", "title": "Stop Atherosclerosis in Native Diabetics Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Cardiovascular Disease", "Hypertension", "Hyperlipidemia", "Diabetes", "Carotid Atherosclerosis" ], "interventions": [ { "name": "FDA approved drugs to treat blood pressure and cholesterol", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Cynthia West", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 548, "start_date": "2003-05", "completion_date": "2007-05-01", "has_results": true, "last_update_posted_date": "2021-07-07", "last_synced_at": "2026-07-22T12:43:42.473Z", "location_count": 4, "location_summary": "Chinle, Arizona • Phoenix, Arizona • Lawton, Oklahoma + 1 more", "locations": [ { "city": "Chinle", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Lawton", "state": "Oklahoma" }, { "city": "Rapid City", "state": "South Dakota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00147251" }, { "nct_id": "NCT01723709", "title": "The MURDOCK Study Community Registry and Biorepository Multiple Sclerosis Cohort", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Multiple Sclerosis" ], "interventions": [], "intervention_types": [], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 973, "start_date": "2010-06", "completion_date": "2017-05", "has_results": false, "last_update_posted_date": "2017-07-21", "last_synced_at": "2026-07-22T12:43:42.473Z", "location_count": 5, "location_summary": "Concord, North Carolina • Davidson, North Carolina • Durham, North Carolina + 2 more", "locations": [ { "city": "Concord", "state": "North Carolina" }, { "city": "Davidson", "state": "North Carolina" }, { "city": "Durham", "state": "North Carolina" }, { "city": "Kannapolis", "state": "North Carolina" }, { "city": "Raleigh", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT01723709" }, { "nct_id": "NCT03808675", "title": "Aerobic Exercise in Parkinson's Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Parkinson's Disease" ], "interventions": [ { "name": "Aerobic walking", "type": "BEHAVIORAL" }, { "name": "Usual care with PD specific health education", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "VA Office of Research and Development", "sponsor_class": "FED", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 57, "start_date": "2019-07-01", "completion_date": "2024-09-30", "has_results": true, "last_update_posted_date": "2026-03-12", "last_synced_at": "2026-07-22T12:43:42.473Z", "location_count": 2, "location_summary": "Iowa City, Iowa", "locations": [ { "city": "Iowa City", "state": "Iowa" }, { "city": "Iowa City", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT03808675" }, { "nct_id": "NCT00256672", "title": "Effectiveness of Bracing in Preventing Scoliosis in Children With Spinal Cord Injury", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Scoliosis" ], "interventions": [ { "name": "Thoraco-Lumbar-Sacral-Orthoses (TLSO) / Flex-Foam", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Shriners Hospitals for Children", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "5 Years", "maximum_age": "16 Years", "sex": "ALL", "summary": "5 Years to 16 Years" }, "enrollment_count": 88, "start_date": "2005-06", "completion_date": "2012-12", "has_results": false, "last_update_posted_date": "2008-06-13", "last_synced_at": "2026-07-22T12:43:42.473Z", "location_count": 3, "location_summary": "Sacramento, California • Chicago, Illinois • Philadelphia, Pennsylvania", "locations": [ { "city": "Sacramento", "state": "California" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00256672" }, { "nct_id": "NCT07026929", "title": "Neuro-immune Interactome in Parkinson's Disease", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Parkinson Disease" ], "interventions": [], "intervention_types": [], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 94, "start_date": "2021-05-10", "completion_date": "2031-06", "has_results": false, "last_update_posted_date": "2026-07-21", "last_synced_at": "2026-07-22T12:43:42.473Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT07026929" }, { "nct_id": "NCT05552157", "title": "A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Alzheimers Disease", "Dementia", "Alzheimers Disease, Familial" ], "interventions": [ { "name": "Remternetug (SC)", "type": "DRUG" }, { "name": "Matching Placebo (Remternetug)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 280, "start_date": "2024-11-22", "completion_date": "2034-08-30", "has_results": false, "last_update_posted_date": "2026-02-13", "last_synced_at": "2026-07-22T12:43:42.473Z", "location_count": 12, "location_summary": "Birmingham, Alabama • La Jolla, California • New Haven, Connecticut + 9 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "La Jolla", "state": "California" }, { "city": "New Haven", "state": "Connecticut" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Park Ridge", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT05552157" } ] }