{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=COVID-19+Lower+Respiratory+Infection",
    "query": {
      "condition": "COVID-19 Lower Respiratory Infection"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T08:15:17.701Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05164744",
      "title": "Cardiac Magnetic Resonance Tissue Characterization in COVID-19 Survivors",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "COVID-19 Pneumonia",
        "COVID-19",
        "COVID-19 Respiratory Infection",
        "COVID-19 Acute Respiratory Distress Syndrome",
        "COVID-19 Lower Respiratory Infection",
        "COVID-19 Acute Bronchitis",
        "Coronavirus Disease 2019"
      ],
      "interventions": [
        {
          "name": "Cardiac MRI",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Echocardiogram",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "6-minute walk test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Questionnaire",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 510,
      "start_date": "2021-07-01",
      "completion_date": "2026-07-30",
      "has_results": false,
      "last_update_posted_date": "2026-01-22",
      "last_synced_at": "2026-05-22T08:15:17.701Z",
      "location_count": 3,
      "location_summary": "Brooklyn, New York • New York, New York",
      "locations": [
        {
          "city": "Brooklyn",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05164744"
    },
    {
      "nct_id": "NCT03808922",
      "title": "Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Lower Respiratory Tract Infection",
        "Parainfluenza",
        "Immunocompromised",
        "COVID-19"
      ],
      "interventions": [
        {
          "name": "DAS181",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "DAS181 COVID-19",
          "type": "DRUG"
        },
        {
          "name": "DAS181 OL",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ansun Biopharma, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 274,
      "start_date": "2019-05-23",
      "completion_date": "2028-09-01",
      "has_results": false,
      "last_update_posted_date": "2026-05-18",
      "last_synced_at": "2026-05-22T08:15:17.701Z",
      "location_count": 49,
      "location_summary": "Duarte, California • Los Angeles, California • Sacramento, California + 33 more",
      "locations": [
        {
          "city": "Duarte",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03808922"
    },
    {
      "nct_id": "NCT05074121",
      "title": "NAC for Attenuation of COVID-19 Symptomatology",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Covid19",
        "COVID-19 Pneumonia",
        "COVID-19 Respiratory Infection",
        "COVID-19 Lower Respiratory Infection",
        "SARS-CoV2 Infection",
        "SARS-CoV-2 Acute Respiratory Disease",
        "SARS-Associated Coronavirus as Cause of Disease Classified Elsewhere",
        "Oxidative Stress"
      ],
      "interventions": [
        {
          "name": "N-acetylcysteine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Cambridge Health Alliance",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2024-03-31",
      "completion_date": "2025-02-01",
      "has_results": false,
      "last_update_posted_date": "2023-08-07",
      "last_synced_at": "2026-05-22T08:15:17.701Z",
      "location_count": 1,
      "location_summary": "Everett, Massachusetts",
      "locations": [
        {
          "city": "Everett",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05074121"
    },
    {
      "nct_id": "NCT05112887",
      "title": "Osteopathic Manipulative Therapy Effects on Prolonged Post-COVID Olfactory Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "COVID-19 Lower Respiratory Infection",
        "SARS-CoV2 Infection"
      ],
      "interventions": [
        {
          "name": "Osteopathic Manipulative Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Ohio University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2021-03-31",
      "completion_date": "2021-09-13",
      "has_results": false,
      "last_update_posted_date": "2021-11-09",
      "last_synced_at": "2026-05-22T08:15:17.701Z",
      "location_count": 1,
      "location_summary": "Dublin, Ohio",
      "locations": [
        {
          "city": "Dublin",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05112887"
    },
    {
      "nct_id": "NCT04949230",
      "title": "A Retrospective Study of COVID-19 Treatments",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Covid19",
        "COVID-19 Pneumonia",
        "COVID-19 Respiratory Infection",
        "COVID-19 Acute Bronchitis",
        "COVID-19 Acute Respiratory Distress Syndrome",
        "COVID-19 Lower Respiratory Infection",
        "SARS-CoV2 Infection",
        "SARS-CoV-2 Acute Respiratory Disease"
      ],
      "interventions": [
        {
          "name": "No Intervention Used",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "ProgenaBiome",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Months",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Months and older"
      },
      "enrollment_count": 300,
      "start_date": "2021-02-19",
      "completion_date": "2024-02-15",
      "has_results": false,
      "last_update_posted_date": "2024-02-29",
      "last_synced_at": "2026-05-22T08:15:17.701Z",
      "location_count": 1,
      "location_summary": "Ventura, California",
      "locations": [
        {
          "city": "Ventura",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04949230"
    },
    {
      "nct_id": "NCT04320862",
      "title": "COVID-19 Pandemic Response Network",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "COVID-19",
        "SARS-CoV-2",
        "Coronavirus",
        "Influenza -Like Illness",
        "Lower Resp Tract Infection",
        "Upper Resp Tract Infection"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 9207,
      "start_date": "2020-04-03",
      "completion_date": "2021-04-30",
      "has_results": false,
      "last_update_posted_date": "2021-09-17",
      "last_synced_at": "2026-05-22T08:15:17.701Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04320862"
    },
    {
      "nct_id": "NCT04829188",
      "title": "Comparative Effectiveness of Readmission Reduction Interventions for Individuals with Sepsis or Pneumonia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sepsis",
        "Pneumonia",
        "Lower Resp Tract Infection",
        "Covid19"
      ],
      "interventions": [
        {
          "name": "Structured Telephone Support (STS)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Low-intensity Remote Patient Monitoring (RPM-Low)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "High-intensity Remote Patient Monitoring (RPM-High)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard Response Team",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced Response Team",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 1288,
      "start_date": "2021-03-30",
      "completion_date": "2024-12-15",
      "has_results": false,
      "last_update_posted_date": "2025-01-16",
      "last_synced_at": "2026-05-22T08:15:17.701Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04829188"
    },
    {
      "nct_id": "NCT05035420",
      "title": "A Noninvasive Multimodal Biosensing Device for Screening and Monitoring Response to Treatment of Infectious Respiratory Diseases",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "COVID-19",
        "Upper Respiratory Infection",
        "Lower Respiratory Infection"
      ],
      "interventions": [
        {
          "name": "Fitbit",
          "type": "DEVICE"
        },
        {
          "name": "Douglas Bag",
          "type": "DEVICE"
        },
        {
          "name": "Periflux 6000 EPOS",
          "type": "DEVICE"
        },
        {
          "name": "BIOPAC",
          "type": "DEVICE"
        },
        {
          "name": "Flowmet",
          "type": "DEVICE"
        },
        {
          "name": "NIRS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "78 Years",
        "sex": "ALL",
        "summary": "18 Years to 78 Years"
      },
      "enrollment_count": 40,
      "start_date": "2022-05-26",
      "completion_date": "2025-08-27",
      "has_results": false,
      "last_update_posted_date": "2025-09-05",
      "last_synced_at": "2026-05-22T08:15:17.701Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05035420"
    },
    {
      "nct_id": "NCT05200858",
      "title": "Transcutaneous Electrical Nerve Stimulation (TENS) in Patients With Postacute Sequelae of Sars-CoV-2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postacute Sequelae of Sars-CoV-2",
        "Post-Acute COVID-19 Syndrome",
        "Widespread Chronic Pain",
        "Fatigue Syndrome, Chronic",
        "Gait, Unsteady"
      ],
      "interventions": [
        {
          "name": "TENS - high-dose",
          "type": "DEVICE"
        },
        {
          "name": "TENS - low-dose",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2022-03-01",
      "completion_date": "2023-12-01",
      "has_results": true,
      "last_update_posted_date": "2024-07-16",
      "last_synced_at": "2026-05-22T08:15:17.701Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05200858"
    },
    {
      "nct_id": "NCT04707534",
      "title": "Comparing the Effects of Different Doses of Dexamethasone to Treat Inpatient COVID-19",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Covid19"
      ],
      "interventions": [
        {
          "name": "Dexamethasone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 110,
      "start_date": "2021-01-21",
      "completion_date": "2022-03-04",
      "has_results": true,
      "last_update_posted_date": "2024-03-29",
      "last_synced_at": "2026-05-22T08:15:17.701Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04707534"
    }
  ]
}