{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Caffeine",
    "query": {
      "condition": "Caffeine"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 202,
    "total_pages": 21,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Caffeine&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:23:46.305Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01721473",
      "title": "Brain Nicotine Receptor Density in Veteran Smokers",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Positron Emission Tomography"
      ],
      "interventions": [
        {
          "name": "positron emission tomography scan",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 184,
      "start_date": "2012-01-01",
      "completion_date": "2016-06-30",
      "has_results": true,
      "last_update_posted_date": "2019-10-07",
      "last_synced_at": "2026-05-22T09:23:46.305Z",
      "location_count": 2,
      "location_summary": "San Diego, California • West Los Angeles, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "West Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01721473"
    },
    {
      "nct_id": "NCT05641194",
      "title": "EaseAlert: Tactile Firefighter Alerting System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Rate",
        "Sleep Habit",
        "Sleep"
      ],
      "interventions": [
        {
          "name": "Legacy Alerting System",
          "type": "DEVICE"
        },
        {
          "name": "Intervention 2: EaseAlert Standalone",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Embry-Riddle Aeronautical University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 47,
      "start_date": "2023-08-26",
      "completion_date": "2025-01-31",
      "has_results": false,
      "last_update_posted_date": "2025-03-13",
      "last_synced_at": "2026-05-22T09:23:46.305Z",
      "location_count": 2,
      "location_summary": "Blue Springs, Missouri • Stillwater, Oklahoma",
      "locations": [
        {
          "city": "Blue Springs",
          "state": "Missouri"
        },
        {
          "city": "Stillwater",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05641194"
    },
    {
      "nct_id": "NCT00205166",
      "title": "Does Caffeine Affect the Sensitivity of Adenosine Perfusion Scans?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "Cardiac SPECT imaging Rest and Stress",
          "type": "PROCEDURE"
        },
        {
          "name": "Caffeine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 50,
      "start_date": "1999-06",
      "completion_date": "2004-12",
      "has_results": false,
      "last_update_posted_date": "2012-10-29",
      "last_synced_at": "2026-05-22T09:23:46.305Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00205166"
    },
    {
      "nct_id": "NCT06232551",
      "title": "Alerting Providers at Patient Hospital Discharge to Consider Prescribing Rivaroxaban to Reduce Venous Thromboembolism",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Venous Thromboembolic Disease",
        "Pulmonary Embolism and Thrombosis",
        "Deep Vein Thrombosis",
        "Hospitalism"
      ],
      "interventions": [
        {
          "name": "EHR (electronic health record) alert",
          "type": "OTHER"
        },
        {
          "name": "No EHR (electronic health record) alert",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Scott C. Woller, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "110 Years",
        "sex": "ALL",
        "summary": "18 Years to 110 Years"
      },
      "enrollment_count": 152000,
      "start_date": "2024-06-01",
      "completion_date": "2025-09-30",
      "has_results": false,
      "last_update_posted_date": "2024-07-17",
      "last_synced_at": "2026-05-22T09:23:46.305Z",
      "location_count": 1,
      "location_summary": "Murray, Utah",
      "locations": [
        {
          "city": "Murray",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06232551"
    },
    {
      "nct_id": "NCT00130026",
      "title": "Caffeine in the Prevention of Post-operative Nausea and Vomiting",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Postoperative Nausea and Vomiting"
      ],
      "interventions": [
        {
          "name": "Caffeine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 135,
      "start_date": "2005-03",
      "completion_date": "2005-10",
      "has_results": false,
      "last_update_posted_date": "2017-02-07",
      "last_synced_at": "2026-05-22T09:23:46.305Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00130026"
    },
    {
      "nct_id": "NCT02594358",
      "title": "Caffeine in Amblyopia Study",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Amblyopia"
      ],
      "interventions": [
        {
          "name": "Caffeine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "13 Years",
        "sex": "ALL",
        "summary": "7 Years to 13 Years"
      },
      "enrollment_count": 0,
      "start_date": "2014-10",
      "completion_date": "2018-12",
      "has_results": false,
      "last_update_posted_date": "2017-03-07",
      "last_synced_at": "2026-05-22T09:23:46.305Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02594358"
    },
    {
      "nct_id": "NCT03019523",
      "title": "The Effect of a Caffeine Blend on Reaction Time, Mental Performance and Focus in Athletic Males",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mental Fatigue"
      ],
      "interventions": [
        {
          "name": "Caffeine Blend",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Sugar Pill",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "University of Mary Hardin-Baylor",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "25 Years",
        "sex": "MALE",
        "summary": "18 Years to 25 Years · Male only"
      },
      "enrollment_count": 31,
      "start_date": "2016-08",
      "completion_date": "2016-12",
      "has_results": false,
      "last_update_posted_date": "2017-01-25",
      "last_synced_at": "2026-05-22T09:23:46.305Z",
      "location_count": 1,
      "location_summary": "Belton, Texas",
      "locations": [
        {
          "city": "Belton",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03019523"
    },
    {
      "nct_id": "NCT02180048",
      "title": "\"The Effects of Caffeine on Overactive Bladder Symptoms and Mental Health in Postmenopausal Women\"",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overactive Bladder",
        "Caffeine",
        "Menopause"
      ],
      "interventions": [
        {
          "name": "400 mg of caffeine/day (Two 200mg pills/day)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "200 mg of caffeine/day (One 200mg pill and one placebo pill)",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Two placebo pills/day",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "58 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "58 Years and older · Female only"
      },
      "enrollment_count": 55,
      "start_date": "2014-07",
      "completion_date": "2018-09-20",
      "has_results": false,
      "last_update_posted_date": "2018-10-25",
      "last_synced_at": "2026-05-22T09:23:46.305Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02180048"
    },
    {
      "nct_id": "NCT04730193",
      "title": "Caffeine and Cerebrovascular Reactivity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Caffeine"
      ],
      "interventions": [
        {
          "name": "Caffeine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "21 Years to 85 Years"
      },
      "enrollment_count": 10,
      "start_date": "2021-02-01",
      "completion_date": "2022-08-01",
      "has_results": false,
      "last_update_posted_date": "2022-08-09",
      "last_synced_at": "2026-05-22T09:23:46.305Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04730193"
    },
    {
      "nct_id": "NCT06441695",
      "title": "Acute Effects of PLT Health Solutions zümXR Extended-Release Caffeine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Caffeine",
        "Cognitive Change",
        "Mood",
        "Mood Change"
      ],
      "interventions": [
        {
          "name": "xumXR extended release caffeine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "immediate release caffeine",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Applied Science & Performance Institute",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "35 Years to 50 Years"
      },
      "enrollment_count": 36,
      "start_date": "2024-06-13",
      "completion_date": "2024-10-25",
      "has_results": false,
      "last_update_posted_date": "2025-09-16",
      "last_synced_at": "2026-05-22T09:23:46.305Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06441695"
    }
  ]
}