{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Caffeine+Withdrawal",
    "query": {
      "condition": "Caffeine Withdrawal"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 7,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T12:08:39.210Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06117280",
      "title": "Effect of Different Dosages of Paraxanthine, the Major Caffeine Metabolite, on Energy and Focus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Energy",
        "Focus",
        "Caffeine Withdrawal"
      ],
      "interventions": [
        {
          "name": "Paraxanthine 200 mg",
          "type": "OTHER"
        },
        {
          "name": "Paraxanthine 300 mg",
          "type": "OTHER"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Iovate Health Sciences International Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 45,
      "start_date": "2023-07-18",
      "completion_date": "2023-10-20",
      "has_results": false,
      "last_update_posted_date": "2023-11-07",
      "last_synced_at": "2026-06-26T12:08:39.210Z",
      "location_count": 1,
      "location_summary": "Santa Monica, California",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06117280"
    },
    {
      "nct_id": "NCT02044757",
      "title": "The Potentially Addictive Properties of Soda: A Feasibility Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Withdrawal Symptoms"
      ],
      "interventions": [
        {
          "name": "SSB withdrawal",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Berkeley",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "13 Years to 18 Years"
      },
      "enrollment_count": 28,
      "start_date": "2013-06",
      "completion_date": "2014-08",
      "has_results": false,
      "last_update_posted_date": "2014-12-09",
      "last_synced_at": "2026-06-26T12:08:39.210Z",
      "location_count": 1,
      "location_summary": "Oakland, California",
      "locations": [
        {
          "city": "Oakland",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02044757"
    },
    {
      "nct_id": "NCT01951872",
      "title": "Treatment for Caffeine Dependence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Caffeine Use Disorder (DSM-5 Condition for Further Study)"
      ],
      "interventions": [
        {
          "name": "Manual-based treatment for caffeine dependence",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 82,
      "start_date": "2013-09",
      "completion_date": "2017-03",
      "has_results": false,
      "last_update_posted_date": "2017-08-18",
      "last_synced_at": "2026-06-26T12:08:39.210Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01951872"
    },
    {
      "nct_id": "NCT00338195",
      "title": "Assessment and Treatment of Caffeine Dependence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Self-identified Problematic Caffeine Use",
        "DSM-IV Substance Dependence as Applied to Caffeine"
      ],
      "interventions": [
        {
          "name": "Individualized caffeine cessation instructions",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 94,
      "start_date": "2001-05",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2013-03-07",
      "last_synced_at": "2026-06-26T12:08:39.210Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00338195"
    },
    {
      "nct_id": "NCT06146517",
      "title": "A Single-Arm, Virtual Clinical Trial to Evaluate the Effects of a Sleep Supporting Beverage and Two Coffee Substitute Products",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep",
        "Mood",
        "Caffeine Withdrawal",
        "Anxiety",
        "Productivity"
      ],
      "interventions": [
        {
          "name": "Clevr Sleeptime",
          "type": "OTHER"
        },
        {
          "name": "Clevr Matcha",
          "type": "OTHER"
        },
        {
          "name": "Clevr Chai",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Clevr Blends",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "28 Years",
        "maximum_age": "42 Years",
        "sex": "FEMALE",
        "summary": "28 Years to 42 Years · Female only"
      },
      "enrollment_count": 32,
      "start_date": "2023-08-31",
      "completion_date": "2024-01-22",
      "has_results": false,
      "last_update_posted_date": "2024-08-22",
      "last_synced_at": "2026-06-26T12:08:39.210Z",
      "location_count": 1,
      "location_summary": "Santa Monica, California",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06146517"
    },
    {
      "nct_id": "NCT04560595",
      "title": "Remote Guided Caffeine Reduction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Caffeine Dependence",
        "Anxiety",
        "Sleep Disturbance",
        "Gastrointestinal Dysfunction",
        "Sleep Initiation and Maintenance Disorders",
        "Caffeine; Sleep Disorder",
        "Caffeine",
        "Caffeine-Induced Anxiety Disorder",
        "Caffeine Withdrawal",
        "Caffeine-Induced Sleep Disorder, Without Use Disorder",
        "Caffeine Abuse",
        "Insomnia",
        "Anxiety Disorders",
        "Sleep Disorder",
        "Heartburn",
        "Diarrhea"
      ],
      "interventions": [
        {
          "name": "Caffeine Reduction Manual",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 109,
      "start_date": "2020-09-10",
      "completion_date": "2023-10-01",
      "has_results": true,
      "last_update_posted_date": "2025-01-14",
      "last_synced_at": "2026-06-26T12:08:39.210Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04560595"
    },
    {
      "nct_id": "NCT04025060",
      "title": "Reducing Sugar-sweetened Beverage Consumption Among Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pediatric Obesity",
        "Diet, Food, and Nutrition"
      ],
      "interventions": [
        {
          "name": "Commercially-available caffeine-free soda",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Carbonated water",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Regular soda",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "George Washington University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "11 Years",
        "sex": "ALL",
        "summary": "8 Years to 11 Years"
      },
      "enrollment_count": 29,
      "start_date": "2019-07-10",
      "completion_date": "2021-05-31",
      "has_results": false,
      "last_update_posted_date": "2022-05-12",
      "last_synced_at": "2026-06-26T12:08:39.210Z",
      "location_count": 1,
      "location_summary": "Washington D.C., District of Columbia",
      "locations": [
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04025060"
    }
  ]
}