{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Calcium+Oxalate+Kidney+Stones",
    "query": {
      "condition": "Calcium Oxalate Kidney Stones"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 23,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Calcium+Oxalate+Kidney+Stones&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-11-15T08:14:22.144Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00381849",
      "title": "Use of an Herbal Preparation to Prevent and Dissolve Kidney Stones",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Cystinuria",
        "Nephrolithiasis, Calcium Oxalate"
      ],
      "interventions": [
        {
          "name": "Cystone",
          "type": "DRUG"
        },
        {
          "name": "Sugar Pill (Placebo)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 20,
      "start_date": "2006-04",
      "completion_date": "2010-06",
      "has_results": true,
      "last_update_posted_date": "2016-02-04",
      "last_synced_at": "2026-11-15T08:14:22.144Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00381849"
    },
    {
      "nct_id": "NCT04430426",
      "title": "Heterozygous Individuals for AGXT and Kidney Stones",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Kidney Stone",
        "Urolithiasis, Calcium Oxalate"
      ],
      "interventions": [
        {
          "name": "Controlled Diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2027-07-01",
      "completion_date": "2032-08-01",
      "has_results": false,
      "last_update_posted_date": "2026-08-31",
      "last_synced_at": "2026-11-15T08:14:22.144Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04430426"
    },
    {
      "nct_id": "NCT00169754",
      "title": "Attached Stone Project: Do Calcium Oxalate Renal Calculi Originate From Randall's Plaque?",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Renal Calculi"
      ],
      "interventions": [
        {
          "name": "mapping kidney anatomy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Indiana Kidney Stone Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 32,
      "start_date": "2005-04",
      "completion_date": "2007-10",
      "has_results": false,
      "last_update_posted_date": "2008-09-17",
      "last_synced_at": "2026-11-15T08:14:22.144Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00169754"
    },
    {
      "nct_id": "NCT01127854",
      "title": "Pilot Study to Evaluate the Contribution of Gene Variants to Idiopathic Urolithiasis",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Kidney Stones",
        "Urolithiasis",
        "Calcium Oxalate Urolithiasis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2900,
      "start_date": "2009-12",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-01-23",
      "last_synced_at": "2026-11-15T08:14:22.144Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01127854"
    },
    {
      "nct_id": "NCT04603898",
      "title": "Oxalate Formation From Ascorbic Acid",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Kidney Stone"
      ],
      "interventions": [
        {
          "name": "Low Oxalate Diet",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Carbon-13 Ascorbic Acid Oral Load",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 90,
      "start_date": "2021-11-15",
      "completion_date": "2027-02-01",
      "has_results": false,
      "last_update_posted_date": "2026-06-09",
      "last_synced_at": "2026-11-15T08:14:22.144Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04603898"
    },
    {
      "nct_id": "NCT03752684",
      "title": "Oxalobacter Formigenes Colonization and Urinary Oxalate Excretion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Calcium Oxalate Urolithiasis"
      ],
      "interventions": [
        {
          "name": "Moderately high oxalate/low calcium diet non-colonized",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Oxalobacter formigenes",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Moderately high oxalate/low calcium diet colonized",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "19 Years to 65 Years"
      },
      "enrollment_count": 26,
      "start_date": "2018-04-02",
      "completion_date": "2025-05-22",
      "has_results": true,
      "last_update_posted_date": "2026-01-30",
      "last_synced_at": "2026-11-15T08:14:22.144Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03752684"
    },
    {
      "nct_id": "NCT01077284",
      "title": "Febuxostat Versus Allopurinol or Placebo in Patients With Hyperuricosuria and Calcium Oxalate Stones",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Hyperuricosuria",
        "Kidney Stones"
      ],
      "interventions": [
        {
          "name": "Febuxostat",
          "type": "DRUG"
        },
        {
          "name": "Allopurinol",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Takeda",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 99,
      "start_date": "2010-02",
      "completion_date": "2011-11",
      "has_results": true,
      "last_update_posted_date": "2013-02-15",
      "last_synced_at": "2026-11-15T08:14:22.144Z",
      "location_count": 28,
      "location_summary": "Birmingham, Alabama • Anchorage, Alaska • Tucson, Arizona + 25 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Anchorage",
          "state": "Alaska"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Costa Mesa",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01077284"
    },
    {
      "nct_id": "NCT02096965",
      "title": "Use of Tolvaptan to Reduce Urinary Supersaturation: a Pilot Proof of Principle Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Nephrolithiasis, Calcium Oxalate",
        "Nephrolithiasis, Calcium Phosphate"
      ],
      "interventions": [
        {
          "name": "Tolvaptan",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2014-03",
      "completion_date": "2015-11",
      "has_results": false,
      "last_update_posted_date": "2016-03-30",
      "last_synced_at": "2026-11-15T08:14:22.144Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02096965"
    },
    {
      "nct_id": "NCT06330246",
      "title": "O. Formigenes Colonization in Calcium Oxalate Kidney Stone Disease",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Kidney Stone",
        "Kidney Calculi",
        "Urolithiasis",
        "Urolithiasis, Calcium Oxalate",
        "Nephrolithiasis",
        "Nephrolithiasis, Calcium Oxalate",
        "Oxalate Urolithiasis",
        "Oxaluria"
      ],
      "interventions": [
        {
          "name": "Low oxalate fixed diets pre-colonization",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Moderately high oxalate fixed diets pre-colonization",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Colonization with Oxalobacter formigenes",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Low oxalate fixed diets post-colonization",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Moderately high oxalate fixed diets post-colonization",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 40,
      "start_date": "2024-04-17",
      "completion_date": "2031-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-10-13",
      "last_synced_at": "2026-11-15T08:14:22.144Z",
      "location_count": 2,
      "location_summary": "Birmingham, Alabama • Dallas, Texas",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06330246"
    },
    {
      "nct_id": "NCT04633811",
      "title": "Effect of Weight Loss on Urinary Oxalate Excretion in Obese Calcium Oxalate Kidney Stone Formers",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Kidney Stone"
      ],
      "interventions": [
        {
          "name": "Low Oxalate Diet before Weight Loss",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Oral load of oxalate and sucralose before Weight Loss",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Optifast VLCD Program",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Optifast VLCD Transition Phase",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Low Oxalate Diet after Weight Loss",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Oral load of oxalate and sucralose after Weight Loss",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "19 Years to 65 Years"
      },
      "enrollment_count": 14,
      "start_date": "2021-12-03",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-09-01",
      "last_synced_at": "2026-11-15T08:14:22.144Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04633811"
    }
  ]
}