{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Calorie+Deficiency",
    "query": {
      "condition": "Calorie Deficiency"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T00:23:04.443Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00050791",
      "title": "Effects of Leptin Treatment on Weight Loss",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Leptin",
          "type": "DRUG"
        },
        {
          "name": "Very Low Calorie Diet",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "Rockefeller University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "20 Years to 45 Years · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2001-03",
      "completion_date": "2009-06",
      "has_results": false,
      "last_update_posted_date": "2010-10-19",
      "last_synced_at": "2026-07-23T00:23:04.443Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00050791"
    },
    {
      "nct_id": "NCT06376604",
      "title": "Fasting Mimicking Diet in Chemotherapy of Gynecologic Malignancies",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cancer, Ovarian",
        "Chemotherapy Effect",
        "Calorie Deficiency",
        "Fasting, Intermittent"
      ],
      "interventions": [
        {
          "name": "Fasting Mimicking Diet",
          "type": "OTHER"
        },
        {
          "name": "Chemotherapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "L-Nutra Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "35 Years to 70 Years · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2021-09-08",
      "completion_date": "2025-12-30",
      "has_results": false,
      "last_update_posted_date": "2024-04-19",
      "last_synced_at": "2026-07-23T00:23:04.443Z",
      "location_count": 1,
      "location_summary": "Knoxville, Tennessee",
      "locations": [
        {
          "city": "Knoxville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06376604"
    },
    {
      "nct_id": "NCT00392873",
      "title": "Increased Calorie Intake to Reverse Energy Deficiency in Exercising Women: Impact on Bone and Menstrual Cyclicity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Menstrual Irregularity"
      ],
      "interventions": [
        {
          "name": "EAMD+Calories",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Penn State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 35 Years · Female only"
      },
      "enrollment_count": 233,
      "start_date": "2006-09",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2017-05-08",
      "last_synced_at": "2026-07-23T00:23:04.443Z",
      "location_count": 1,
      "location_summary": "University Park, Pennsylvania",
      "locations": [
        {
          "city": "University Park",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00392873"
    },
    {
      "nct_id": "NCT02858336",
      "title": "CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hormones"
      ],
      "interventions": [
        {
          "name": "NEA",
          "type": "BEHAVIORAL"
        },
        {
          "name": "DEA",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "National Institute of Environmental Health Sciences (NIEHS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "28 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 28 Years · Female only"
      },
      "enrollment_count": 38,
      "start_date": "2017-01-12",
      "completion_date": "2019-06-29",
      "has_results": false,
      "last_update_posted_date": "2026-07-17",
      "last_synced_at": "2026-07-23T00:23:04.443Z",
      "location_count": 1,
      "location_summary": "Research Triangle Park, North Carolina",
      "locations": [
        {
          "city": "Research Triangle Park",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02858336"
    },
    {
      "nct_id": "NCT00983983",
      "title": "High Fat/High Calorie Trial in Amyotrophic Lateral Sclerosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Amyotrophic Lateral Sclerosis"
      ],
      "interventions": [
        {
          "name": "Oxepa",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Jevity 1.5",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Jevity 1.0",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 28,
      "start_date": "2009-10",
      "completion_date": "2013-05",
      "has_results": true,
      "last_update_posted_date": "2015-02-27",
      "last_synced_at": "2026-07-23T00:23:04.443Z",
      "location_count": 13,
      "location_summary": "Phoenix, Arizona • Irvine, California • San Francisco, California + 10 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00983983"
    },
    {
      "nct_id": "NCT01292395",
      "title": "Effects of Dietary Protein on Musculoskeletal Health During Calorie Deficiency",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Weight Loss",
        "Muscle Loss",
        "Bone Loss"
      ],
      "interventions": [
        {
          "name": "Dietary Protein Intake",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "United States Army Research Institute of Environmental Medicine",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "42 Years",
        "sex": "ALL",
        "summary": "18 Years to 42 Years"
      },
      "enrollment_count": 42,
      "start_date": "2010-09",
      "completion_date": "2011-11",
      "has_results": false,
      "last_update_posted_date": "2017-08-14",
      "last_synced_at": "2026-07-23T00:23:04.443Z",
      "location_count": 1,
      "location_summary": "Grand Forks, North Dakota",
      "locations": [
        {
          "city": "Grand Forks",
          "state": "North Dakota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01292395"
    },
    {
      "nct_id": "NCT00000873",
      "title": "A Study on the Effect of High-Calorie Infant Formula on Growth and Nutrition in HIV-Infected Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "Infant Formula",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "17 Days",
        "sex": "ALL",
        "summary": "1 Day to 17 Days"
      },
      "enrollment_count": 2400,
      "start_date": null,
      "completion_date": "2005-09",
      "has_results": false,
      "last_update_posted_date": "2013-10-07",
      "last_synced_at": "2026-07-23T00:23:04.443Z",
      "location_count": 62,
      "location_summary": "Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 46 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Long Beach",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00000873"
    },
    {
      "nct_id": "NCT05290064",
      "title": "Effect of Ultra-processed Versus Unprocessed Diets on Energy Metabolism",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Diet",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Ultra-processed food, high energy density",
          "type": "OTHER"
        },
        {
          "name": "Ultra-processed food, both low",
          "type": "OTHER"
        },
        {
          "name": "Ultra-processed food, both high",
          "type": "OTHER"
        },
        {
          "name": "Unprocessed food diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 66,
      "start_date": "2022-11-04",
      "completion_date": "2025-08-15",
      "has_results": false,
      "last_update_posted_date": "2025-08-28",
      "last_synced_at": "2026-07-23T00:23:04.443Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05290064"
    },
    {
      "nct_id": "NCT04393909",
      "title": "Improving Safety of Diagnosis and Therapy in the Inpatient Setting",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Delirium",
        "Confusion",
        "Mental Status Change",
        "Back Pain",
        "Hip Pain Chronic",
        "Chest Pain",
        "Asthma",
        "COPD",
        "Cellulitis",
        "Soft Tissue Infections",
        "Cough",
        "Deep Vein Thrombosis",
        "Pulmonary Embolism",
        "Venous Thromboembolism",
        "Dyspnea",
        "Electrolyte Metabolism Abnormal",
        "Fever",
        "Failure to Thrive",
        "Weakness",
        "Protein-Calorie Malnutrition",
        "Headache",
        "Neck Pain",
        "Hypoxia",
        "Pneumonia",
        "Sepsis",
        "Syncope",
        "Vomiting",
        "Diarrhea",
        "Leg Pain",
        "Abdominal Pain"
      ],
      "interventions": [
        {
          "name": "Diagnostic Uncertainty Educational Curriculum",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Diagnostic Timeout",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Diagnostic (Dx) Questionnaire",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhancements to Epic-integrated Quality & Safety Dashboard",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 700,
      "start_date": "2019-07-01",
      "completion_date": "2021-12-30",
      "has_results": false,
      "last_update_posted_date": "2022-07-26",
      "last_synced_at": "2026-07-23T00:23:04.443Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04393909"
    },
    {
      "nct_id": "NCT03440593",
      "title": "Indirect Calorimetry Usage and Effect in Ventilator-free Days and Muscle Thickness in Septic Ventilated Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sepsis",
        "Critical Illness",
        "Respiratory Failure",
        "Nutrition Disorders",
        "Calorie Deficiency",
        "Diaphragm Injury",
        "Quadriceps Muscle Atrophy"
      ],
      "interventions": [
        {
          "name": "Caloric delivery will target results of IC measurement.",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Baylor Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2018-09-10",
      "completion_date": "2019-10-03",
      "has_results": false,
      "last_update_posted_date": "2020-10-22",
      "last_synced_at": "2026-07-23T00:23:04.443Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03440593"
    }
  ]
}