{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Carbon+Dioxide+Insufflation",
    "query": {
      "condition": "Carbon Dioxide Insufflation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 15,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Carbon+Dioxide+Insufflation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T00:20:16.419Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00685386",
      "title": "A Randomized Controlled Trial (RCT) of Carbon Dioxide Versus Air Insufflation During Endoscopic Retrograde Cholangiopancreatography (ERCP)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cholestasis"
      ],
      "interventions": [
        {
          "name": "CO2 insufflation",
          "type": "OTHER"
        },
        {
          "name": "Room air insufflation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 74,
      "start_date": "2008-06",
      "completion_date": "2009-02",
      "has_results": false,
      "last_update_posted_date": "2013-01-24",
      "last_synced_at": "2026-07-24T00:20:16.419Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00685386"
    },
    {
      "nct_id": "NCT03811522",
      "title": "Comparison Air Versus Carbon Dioxide Insufflation in Single Balloon Anterograde Enteroscopy",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Carbon Dioxide Insufflation",
        "Anterograde Single Balloon Enteroscopy"
      ],
      "interventions": [
        {
          "name": "carbon dioxide insufflation",
          "type": "OTHER"
        },
        {
          "name": "Air insufflation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "North Eastern Ohio Gastroenterology and Endoscopy center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 50,
      "start_date": "2019-01-01",
      "completion_date": "2020-06-01",
      "has_results": false,
      "last_update_posted_date": "2019-02-15",
      "last_synced_at": "2026-07-24T00:20:16.419Z",
      "location_count": 1,
      "location_summary": "Warren, Ohio",
      "locations": [
        {
          "city": "Warren",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03811522"
    },
    {
      "nct_id": "NCT02409979",
      "title": "Impact of Carbon Dioxide Insufflation and Water Exchange on Post-Colonoscopy Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Abdominal Pain"
      ],
      "interventions": [
        {
          "name": "Carbon dioxide method",
          "type": "OTHER"
        },
        {
          "name": "Water Exchange-CO2",
          "type": "OTHER"
        },
        {
          "name": "Water Exchange-AI",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Presidio Ospedaliero Santa Barbara",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 246,
      "start_date": "2015-04",
      "completion_date": "2015-11",
      "has_results": false,
      "last_update_posted_date": "2015-11-05",
      "last_synced_at": "2026-07-24T00:20:16.419Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02409979"
    },
    {
      "nct_id": "NCT02790359",
      "title": "Carbon Dioxide Insufflation Versus Conventional Air Insufflation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Abdominal Pain"
      ],
      "interventions": [
        {
          "name": "Air",
          "type": "OTHER"
        },
        {
          "name": "Carbon dioxide",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "8 Years to 21 Years"
      },
      "enrollment_count": 100,
      "start_date": "2015-03",
      "completion_date": "2016-03",
      "has_results": false,
      "last_update_posted_date": "2019-12-13",
      "last_synced_at": "2026-07-24T00:20:16.419Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02790359"
    },
    {
      "nct_id": "NCT02654808",
      "title": "AirSeal®Insufflation Trocar/CO2 Absorption Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gynecologic Diseases"
      ],
      "interventions": [
        {
          "name": "AirSeal trocar",
          "type": "DEVICE"
        },
        {
          "name": "Standard trocar",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 132,
      "start_date": "2016-05",
      "completion_date": "2017-05",
      "has_results": true,
      "last_update_posted_date": "2021-09-16",
      "last_synced_at": "2026-07-24T00:20:16.419Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02654808"
    },
    {
      "nct_id": "NCT02619656",
      "title": "A Trial of Supplemental CO2 Versus Room Air in Percutaneous Endoscopic Gastrostomy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pneumoperitoneum"
      ],
      "interventions": [
        {
          "name": "CO2 insufflation",
          "type": "PROCEDURE"
        },
        {
          "name": "Ambient air insufflation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 35,
      "start_date": "2012-04",
      "completion_date": "2015-06",
      "has_results": false,
      "last_update_posted_date": "2015-12-02",
      "last_synced_at": "2026-07-24T00:20:16.419Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02619656"
    },
    {
      "nct_id": "NCT05838300",
      "title": "Lexion AP 50/30 Warmed Humidified Real Time CO2 Insufflation vs Airseal Recirculated CO2/Air Insufflation in Minimally Invasive Bariatric (Gastric Bypass) Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bariatric Surgery"
      ],
      "interventions": [
        {
          "name": "Warm humidified CO2",
          "type": "DEVICE"
        },
        {
          "name": "Dry CO2",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 54,
      "start_date": "2023-05-19",
      "completion_date": "2025-12-30",
      "has_results": false,
      "last_update_posted_date": "2025-06-13",
      "last_synced_at": "2026-07-24T00:20:16.419Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05838300"
    },
    {
      "nct_id": "NCT06918730",
      "title": "U-POEM vs CO2-POEM",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Esophageal Motility Disorders"
      ],
      "interventions": [
        {
          "name": "U-POEM",
          "type": "PROCEDURE"
        },
        {
          "name": "CO2-POEM",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "AdventHealth",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2025-02-11",
      "completion_date": "2026-03-03",
      "has_results": false,
      "last_update_posted_date": "2026-05-15",
      "last_synced_at": "2026-07-24T00:20:16.419Z",
      "location_count": 1,
      "location_summary": "Orlando, Florida",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06918730"
    },
    {
      "nct_id": "NCT04541667",
      "title": "Is End Tidal CO2 Level Elevation During Upper Endoscopy With CO2 Gas Insufflation Physiologically Significant",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Endoscopy"
      ],
      "interventions": [
        {
          "name": "Air",
          "type": "OTHER"
        },
        {
          "name": "Carbon Dioxide",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "19 Years",
        "sex": "ALL",
        "summary": "6 Months to 19 Years"
      },
      "enrollment_count": 200,
      "start_date": "2019-11-18",
      "completion_date": "2022-05-31",
      "has_results": true,
      "last_update_posted_date": "2023-10-10",
      "last_synced_at": "2026-07-24T00:20:16.419Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04541667"
    },
    {
      "nct_id": "NCT02117232",
      "title": "Effectiveness and Safety of the Colonoscopy With \"Visualization\" Balloon",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Colonic Adenomatous Polyps"
      ],
      "interventions": [
        {
          "name": "Visualization balloon",
          "type": "DEVICE"
        },
        {
          "name": "Traditional CO2 insufflation colonoscopy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mercy Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "17 Years to 90 Years"
      },
      "enrollment_count": 216,
      "start_date": "2014-03",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2018-08-21",
      "last_synced_at": "2026-07-24T00:20:16.419Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02117232"
    }
  ]
}