{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cardiac%3B+Dyspnea&page=2",
    "query": {
      "condition": "Cardiac; Dyspnea",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cardiac%3B+Dyspnea&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T16:00:40.114Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04886128",
      "title": "Improving Diagnostic Accuracy for Acute Heart Failure",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Acute Heart Failure",
        "Dyspnea",
        "Dyspnea; Cardiac"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2469,
      "start_date": "2021-08-31",
      "completion_date": "2026-05-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-06",
      "last_synced_at": "2026-07-24T16:00:40.114Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04886128"
    },
    {
      "nct_id": "NCT01193998",
      "title": "Impact of Validated Diagnostic Prediction Model of Acute Heart Failure in the Emergency Department",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dyspnea",
        "Acute Heart Failure",
        "Shortness of Breath"
      ],
      "interventions": [
        {
          "name": "Treatment as per model probability",
          "type": "OTHER"
        },
        {
          "name": "Treatment as per usual care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Unity Health Toronto",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 186,
      "start_date": "2010-09",
      "completion_date": "2014-06",
      "has_results": false,
      "last_update_posted_date": "2014-06-16",
      "last_synced_at": "2026-07-24T16:00:40.114Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01193998"
    },
    {
      "nct_id": "NCT04433546",
      "title": "Pemziviptadil (PB1046), a Long-acting, Sustained Release Human VIP Analogue, Intended to Provide Clinical Improvement to Hospitalized COVID-19 Patients at High Risk for Rapid Clinical Deterioration and Acute Respiratory Distress Syndrome (ARDS).",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Respiratory Distress Syndrome",
        "Coronavirus",
        "Hypoxic Respiratory Failure",
        "Hypoxemic Respiratory Failure",
        "Respiratory Complication",
        "Respiratory Insufficiency",
        "Cardiac Dysfunction",
        "Pneumonia",
        "Pulmonary Edema",
        "Pulmonary Inflammation",
        "Respiratory Failure",
        "Cytokine Storm",
        "COVID 19",
        "SARS-CoV-2",
        "Cardiac Event",
        "Cardiac Complication",
        "Cardiac Failure",
        "Cardiac Infarct"
      ],
      "interventions": [
        {
          "name": "Pemziviptadil (PB1046)",
          "type": "DRUG"
        },
        {
          "name": "Low Dose (10 mg) Control",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "PhaseBio Pharmaceuticals Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 54,
      "start_date": "2020-07-15",
      "completion_date": "2020-12-02",
      "has_results": false,
      "last_update_posted_date": "2020-12-11",
      "last_synced_at": "2026-07-24T16:00:40.114Z",
      "location_count": 4,
      "location_summary": "Jacksonville, Florida • Sarasota, Florida • Kansas City, Kansas + 1 more",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        },
        {
          "city": "Kansas City",
          "state": "Kansas"
        },
        {
          "city": "Silver Spring",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04433546"
    },
    {
      "nct_id": "NCT02291237",
      "title": "Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Hypertrophic Cardiomyopathy"
      ],
      "interventions": [
        {
          "name": "Eleclazine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Gilead Sciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 172,
      "start_date": "2015-02-05",
      "completion_date": "2017-02-17",
      "has_results": true,
      "last_update_posted_date": "2018-09-24",
      "last_synced_at": "2026-07-24T16:00:40.114Z",
      "location_count": 26,
      "location_summary": "Los Angeles, California • Stanford, California • New Haven, Connecticut + 16 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Athens",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02291237"
    },
    {
      "nct_id": "NCT01132846",
      "title": "Renal Optimization Strategies Evaluation in Acute Heart Failure and Reliable Evaluation of Dyspnea in the Heart Failure Network (ROSE) Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Acute Heart Failure"
      ],
      "interventions": [
        {
          "name": "Placebo",
          "type": "OTHER"
        },
        {
          "name": "Nesiritide",
          "type": "DRUG"
        },
        {
          "name": "Dopamine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 360,
      "start_date": "2010-08",
      "completion_date": "2013-06",
      "has_results": true,
      "last_update_posted_date": "2014-08-21",
      "last_synced_at": "2026-07-24T16:00:40.114Z",
      "location_count": 7,
      "location_summary": "Boston, Massachusetts • Minneapolis, Minnesota • Rochester, Minnesota + 4 more",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01132846"
    },
    {
      "nct_id": "NCT05723679",
      "title": "Targeting Breathing Limitations to Improve Functional Outcomes in HFpEF",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Failure With Preserved Ejection Fraction",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "HeO2 gas mixture",
          "type": "OTHER"
        },
        {
          "name": "Room air gas mixture",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "55 Years to 90 Years"
      },
      "enrollment_count": 78,
      "start_date": "2023-07-01",
      "completion_date": "2029-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-07",
      "last_synced_at": "2026-07-24T16:00:40.114Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05723679"
    },
    {
      "nct_id": "NCT00475852",
      "title": "A Study Testing the Effectiveness of Nesiritide in Patients With Acute Decompensated Heart Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Heart Decompensation"
      ],
      "interventions": [
        {
          "name": "Nesiritide",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Scios, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 7141,
      "start_date": "2007-05",
      "completion_date": "2011-03",
      "has_results": true,
      "last_update_posted_date": "2013-03-08",
      "last_synced_at": "2026-07-24T16:00:40.114Z",
      "location_count": 171,
      "location_summary": "Huntsville, Alabama • Mobile, Alabama • Anchorage, Alaska + 168 more",
      "locations": [
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Anchorage",
          "state": "Alaska"
        },
        {
          "city": "Gilbert",
          "state": "Arizona"
        },
        {
          "city": "Scottsdale",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00475852"
    },
    {
      "nct_id": "NCT02248831",
      "title": "Evaluation of Cardiopulmonary Diseases by Ultrasound",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dyspnea",
        "Acute Decompensated Heart Failure"
      ],
      "interventions": [
        {
          "name": "Recording Doppler ultrasound signals noninvasively",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Echosense Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 600,
      "start_date": "2014-09",
      "completion_date": "2018-12",
      "has_results": false,
      "last_update_posted_date": "2019-02-08",
      "last_synced_at": "2026-07-24T16:00:40.114Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02248831"
    },
    {
      "nct_id": "NCT01747785",
      "title": "Myocardial Performance at Rest and During Exercise in Heart Failure With Preserved Ejection Fraction",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "Cardiac rehabilitation",
          "type": "OTHER"
        },
        {
          "name": "Myocardial deformation imaging",
          "type": "OTHER"
        },
        {
          "name": "Cardiopulmonary exercise test",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2012-06",
      "completion_date": "2015-07",
      "has_results": false,
      "last_update_posted_date": "2016-05-17",
      "last_synced_at": "2026-07-24T16:00:40.114Z",
      "location_count": 1,
      "location_summary": "La Crosse, Wisconsin",
      "locations": [
        {
          "city": "La Crosse",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01747785"
    },
    {
      "nct_id": "NCT06172699",
      "title": "Assert-IQ Implantable Cardiac Monitor (ICM) Post Market Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Atrial Fibrillation Paroxysmal",
        "Atrial Fibrillation, Persistent",
        "Cardiac Arrhythmia",
        "Ablation"
      ],
      "interventions": [
        {
          "name": "Holter monitoring in patients who have been successfully implanted with an Abbott Assert-IQ ICM device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 151,
      "start_date": "2024-01-01",
      "completion_date": "2025-11-10",
      "has_results": false,
      "last_update_posted_date": "2026-05-13",
      "last_synced_at": "2026-07-24T16:00:40.114Z",
      "location_count": 11,
      "location_summary": "San Diego, California • Orlando, Florida • Overland Park, Kansas + 8 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Overland Park",
          "state": "Kansas"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Albany",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06172699"
    }
  ]
}