{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cardiac+Defect",
    "query": {
      "condition": "Cardiac Defect"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 101,
    "total_pages": 11,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cardiac+Defect&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T19:18:43.931Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01993264",
      "title": "Fetal Cardiac Strain Imaging Research",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Myocardial Deformation"
      ],
      "interventions": [
        {
          "name": "Fetal Echocardiogram",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 64 Years · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2013-10",
      "completion_date": "2020-11-03",
      "has_results": false,
      "last_update_posted_date": "2022-03-02",
      "last_synced_at": "2026-06-26T19:18:43.931Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01993264"
    },
    {
      "nct_id": "NCT06529575",
      "title": "Evaluating the Relationship Between Skin Color and Pulse Oximeter Accuracy in Children",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pediatric ALL",
        "Cardiac Defect"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Weeks",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "4 Weeks to 18 Years"
      },
      "enrollment_count": 650,
      "start_date": "2024-08-14",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2025-09-12",
      "last_synced_at": "2026-06-26T19:18:43.931Z",
      "location_count": 3,
      "location_summary": "New York, New York • Philadelphia, Pennsylvania • Houston, Texas",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06529575"
    },
    {
      "nct_id": "NCT03373929",
      "title": "Stitch Closure of PFO and Septal Repair",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Foramen Ovale, Patent",
        "Septal Defect, Atrial",
        "Septal Defect, Heart"
      ],
      "interventions": [
        {
          "name": "PFO Closure Rate",
          "type": "DEVICE"
        },
        {
          "name": "Published PFO Device Closure",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "HeartStitch.Com",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 250,
      "start_date": "2017-11-20",
      "completion_date": "2022-11-20",
      "has_results": false,
      "last_update_posted_date": "2017-12-14",
      "last_synced_at": "2026-06-26T19:18:43.931Z",
      "location_count": 1,
      "location_summary": "Falls Church, Virginia",
      "locations": [
        {
          "city": "Falls Church",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03373929"
    },
    {
      "nct_id": "NCT06699056",
      "title": "AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ventricular Ejection Fraction",
        "LVF",
        "LV Dysfunction",
        "Atrial Enlargement",
        "Conduction Defect",
        "Heart Failure",
        "Valvular Heart Disease",
        "Ischemic Heart Disease",
        "Cardiotoxicity",
        "Myocardial Infarction",
        "Dilated Cardiomyopathy",
        "HFrEF - Heart Failure With Reduced Ejection Fraction",
        "HFpEF - Heart Failure With Preserved Ejection Fraction",
        "Syncope",
        "Remodeling, Cardiac"
      ],
      "interventions": [
        {
          "name": "15-minutes of sitting during COR ECG Acquistion",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Peerbridge Health, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2000,
      "start_date": "2024-11-21",
      "completion_date": "2027-11-15",
      "has_results": false,
      "last_update_posted_date": "2026-06-01",
      "last_synced_at": "2026-06-26T19:18:43.931Z",
      "location_count": 8,
      "location_summary": "Orange, California • Pasadena, California • Detroit, Michigan + 5 more",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Pasadena",
          "state": "California"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Hackensack",
          "state": "New Jersey"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06699056"
    },
    {
      "nct_id": "NCT01120964",
      "title": "Intravenous L-Citrulline to Treat Children Undergoing Heart Bypass Surgery : Revised Protocol",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Atrial Septal Defect",
        "Ventricular Septal Defect",
        "Atrioventricular Septal Defect"
      ],
      "interventions": [
        {
          "name": "Intravenous L-Citrulline",
          "type": "DRUG"
        },
        {
          "name": "Placebo of Intravenous L-Citrulline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Asklepion Pharmaceuticals, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Years",
        "sex": "ALL",
        "summary": "Up to 6 Years"
      },
      "enrollment_count": 22,
      "start_date": "2010-09",
      "completion_date": "2012-04",
      "has_results": true,
      "last_update_posted_date": "2022-07-27",
      "last_synced_at": "2026-06-26T19:18:43.931Z",
      "location_count": 2,
      "location_summary": "St Louis, Missouri • Cincinnati, Ohio",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01120964"
    },
    {
      "nct_id": "NCT04452201",
      "title": "Parent Communication for Feeding an Infant With a Heart Defect",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Communication",
        "Heart Defects, Congenital",
        "Infant Conditions"
      ],
      "interventions": [
        {
          "name": "Guided Participation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 35,
      "start_date": "2015-02-25",
      "completion_date": "2019-06-24",
      "has_results": false,
      "last_update_posted_date": "2020-07-01",
      "last_synced_at": "2026-06-26T19:18:43.931Z",
      "location_count": 2,
      "location_summary": "Madison, Wisconsin • Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04452201"
    },
    {
      "nct_id": "NCT00581308",
      "title": "Long-term Safety Study of the GORE® HELEX® Septal Occluder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Septal Defect, Atrial"
      ],
      "interventions": [
        {
          "name": "GORE® HELEX® Septal Occluder",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "W.L.Gore & Associates",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 215,
      "start_date": "2006-08",
      "completion_date": "2014-10",
      "has_results": true,
      "last_update_posted_date": "2018-02-19",
      "last_synced_at": "2026-06-26T19:18:43.931Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00581308"
    },
    {
      "nct_id": "NCT03023644",
      "title": "Improving Neurodevelopmental Outcomes in Children With Congenital Heart Disease: An Intervention Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Congenital Heart Defect",
        "Executive Function",
        "Children",
        "Neurodevelopmental Disorders",
        "Working Memory",
        "Infant Open Heart Surgery"
      ],
      "interventions": [
        {
          "name": "Cogmed Working Memory Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "7 Years to 12 Years"
      },
      "enrollment_count": 106,
      "start_date": "2017-02-21",
      "completion_date": "2020-09-30",
      "has_results": false,
      "last_update_posted_date": "2021-02-01",
      "last_synced_at": "2026-06-26T19:18:43.931Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03023644"
    },
    {
      "nct_id": "NCT02968264",
      "title": "Tetralogy of Fallot for Life",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Tetralogy of Fallot",
        "Congenital Heart Disease",
        "Congenital Heart Defect"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Population Health Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1108,
      "start_date": "2015-06-08",
      "completion_date": "2022-07-01",
      "has_results": false,
      "last_update_posted_date": "2022-12-21",
      "last_synced_at": "2026-06-26T19:18:43.931Z",
      "location_count": 2,
      "location_summary": "Orlando, Florida • New York, New York",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02968264"
    },
    {
      "nct_id": "NCT01773252",
      "title": "Right to Left Cardiac Shunt Detection",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Right to Left Shunt",
        "Patent Foramen Ovale",
        "Atrial Septal Defect"
      ],
      "interventions": [
        {
          "name": "Flow Detection System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Cardiox Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 141,
      "start_date": "2012-11",
      "completion_date": "2015-11",
      "has_results": false,
      "last_update_posted_date": "2015-11-13",
      "last_synced_at": "2026-06-26T19:18:43.931Z",
      "location_count": 8,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • Aurora, Colorado + 5 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01773252"
    }
  ]
}