{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cardiac+Failure&page=13", "query": { "condition": "Cardiac Failure", "page": 13 }, "page_size": 10 }, "pagination": { "page": 13, "page_size": 10, "total_count": 2565, "total_pages": 257, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cardiac+Failure&page=14&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cardiac+Failure&page=12&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-22T00:31:12.816Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT07830758", "title": "Resmetirom in Patients With MASH and HFpEF", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "MASH - Metabolic Dysfunction-Associated Steatohepatitis", "Heart Failure With Preserved Ejection Fraction (HFPEF)" ], "interventions": [ { "name": "Resmetirom", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Madrigal Pharmaceuticals, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 90, "start_date": "2026-09", "completion_date": "2027-12", "has_results": false, "last_update_posted_date": "2026-10-16", "last_synced_at": "2026-10-22T00:31:12.816Z", "location_count": 5, "location_summary": "Peoria, Arizona • Oxnard, California • Fort Myers, Florida + 2 more", "locations": [ { "city": "Peoria", "state": "Arizona" }, { "city": "Oxnard", "state": "California" }, { "city": "Fort Myers", "state": "Florida" }, { "city": "Riverview", "state": "Florida" }, { "city": "University Park", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07830758" }, { "nct_id": "NCT01520714", "title": "Effect of Posture on Left Ventricular (LV) Transvenous Lead Capture Thresholds (EXPECT)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Congestive Heart Failure" ], "interventions": [ { "name": "Medtronic 4195 active fixation LV lead and Medtronic passive fixation LV lead", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Baylor Research Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 11, "start_date": "2009-12", "completion_date": "2011-12", "has_results": true, "last_update_posted_date": "2014-05-26", "last_synced_at": "2026-10-22T00:31:12.816Z", "location_count": 1, "location_summary": "Plano, Texas", "locations": [ { "city": "Plano", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01520714" }, { "nct_id": "NCT01431326", "title": "Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Adenovirus", "Anesthesia", "Anxiety", "Anxiolysis", "Autism", "Autistic Disorder", "Bacterial Meningitis", "Bacterial Septicemia", "Benzodiazepine", "Bipolar Disorder", "Bone and Joint Infections", "Central Nervous System Infections", "Convulsions", "Cytomegalovirus Retinitis", "Early-onset Schizophrenia Spectrum Disorders", "Epilepsy", "General Anesthesia", "Gynecologic Infections", "Herpes Simplex Virus", "Infantile Hemangioma", "Infection", "Inflammation", "Inflammatory Conditions", "Intra-abdominal Infections", "Lower Respiratory Tract Infections", "Migraines", "Pain", "Pneumonia", "Schizophrenia", "Sedation", "Seizures", "Skeletal Muscle Spasms", "Skin and Skin-structure Infections", "Treatment-resistant Schizophrenia", "Urinary Tract Infections", "Withdrawal", "Sepsis", "Gram-negative Infection", "Bradycardia", "Cardiac Arrest", "Cardiac Arrhythmia", "Staphylococcal Infections", "Nosocomial Pneumonia", "Neuromuscular Blockade", "Methicillin Resistant Staphylococcus Aureus", "Endocarditis", "Neutropenia", "Headache", "Fibrinolytic Bleeding", "Pulmonary Arterial Hypertension", "CMV Retinitis", "Hypertension", "Chronic Kidney Diseases", "Hyperaldosteronism", "Hypokalemia", "Heart Failure", "Hemophilia", "Heavy Menstrual Bleeding", "Insomnia" ], "interventions": [ { "name": "The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daniel Benjamin", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "21 Years", "sex": "ALL", "summary": "Up to 21 Years" }, "enrollment_count": 3520, "start_date": "2011-11", "completion_date": "2019-11", "has_results": false, "last_update_posted_date": "2023-09-06", "last_synced_at": "2026-10-22T00:31:12.816Z", "location_count": 43, "location_summary": "Anchorage, Alaska • Little Rock, Arkansas • La Jolla, California + 37 more", "locations": [ { "city": "Anchorage", "state": "Alaska" }, { "city": "Little Rock", "state": "Arkansas" }, { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01431326" }, { "nct_id": "NCT07172971", "title": "Sodium/Glucose Cotransporter-2 Inhibitors (SGLT2i) Therapy in Duchenne Cardiomyopathy", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Duchenne Muscular Dystrophy (DMD)" ], "interventions": [ { "name": "SGLT-2 inhibitor", "type": "DRUG" }, { "name": "SGLT2 inhibitor", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "8 Years", "maximum_age": "18 Years", "sex": "MALE", "summary": "8 Years to 18 Years · Male only" }, "enrollment_count": 10, "start_date": "2026-07-01", "completion_date": "2028-02-01", "has_results": false, "last_update_posted_date": "2026-08-24", "last_synced_at": "2026-10-22T00:31:12.816Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT07172971" }, { "nct_id": "NCT02596087", "title": "Improving Quality by Maintaining Accurate Problems in the EHR", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Asthma", "Atrial Fibrillation", "Chronic Obstructive Pulmonary Disease", "Coronary Artery Disease", "Congestive Heart Failure", "Hyperlipidemia", "Hypertension", "Myocardial Infarction", "Sickle Cell Disease", "Sleep Apnea", "Smoking", "Stroke", "Tuberculosis" ], "interventions": [ { "name": "Problem List Suggestion", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 2386, "start_date": "2016-04", "completion_date": null, "has_results": false, "last_update_posted_date": "2023-02-08", "last_synced_at": "2026-10-22T00:31:12.816Z", "location_count": 4, "location_summary": "Boston, Massachusetts • Portland, Oregon • Camp Hill, Pennsylvania + 1 more", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "Portland", "state": "Oregon" }, { "city": "Camp Hill", "state": "Pennsylvania" }, { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT02596087" }, { "nct_id": "NCT03173157", "title": "Effect of Targeted Interventions to Improve Value Based Health Care for Inpatient Cardiology Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Heart Failure", "Heart Diseases" ], "interventions": [ { "name": "Value Feedback Email", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 183, "start_date": "2017-02-27", "completion_date": "2017-12-31", "has_results": false, "last_update_posted_date": "2018-08-10", "last_synced_at": "2026-10-22T00:31:12.816Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT03173157" }, { "nct_id": "NCT03310099", "title": "Unsaturated Fatty Acids Enriched-diet to Improve Cardiorespiratory Fitness, Metabolic Flexibility and Glucose Tolerance in Obese Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Heart Failure With Normal Ejection Fraction", "Obesity" ], "interventions": [ { "name": "Increasing daily unsaturated fatty acid consumption", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Virginia Commonwealth University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 16, "start_date": "2017-10-23", "completion_date": "2018-10-04", "has_results": false, "last_update_posted_date": "2019-04-18", "last_synced_at": "2026-10-22T00:31:12.816Z", "location_count": 1, "location_summary": "Richmond, Virginia", "locations": [ { "city": "Richmond", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT03310099" }, { "nct_id": "NCT07141914", "title": "A Master Protocol for Semaglutide Effects on Cardiovascular and Obesity-related Outcomes in People With Overweight or Obesity in the Real World", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Overweight", "Obesity", "Heart Failure (HF)", "Atherosclerotic Cardiovascular Disease (ASCVD)", "Primary Prevention" ], "interventions": [ { "name": "No treatment given", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Novo Nordisk A/S", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "45 Years", "maximum_age": null, "sex": "ALL", "summary": "45 Years and older" }, "enrollment_count": 285327, "start_date": "2025-08-29", "completion_date": "2025-12-19", "has_results": false, "last_update_posted_date": "2026-01-23", "last_synced_at": "2026-10-22T00:31:12.816Z", "location_count": 1, "location_summary": "Plainsboro, New Jersey", "locations": [ { "city": "Plainsboro", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT07141914" }, { "nct_id": "NCT04766892", "title": "A Study of Mavacamten in Participants With HFpEF and Elevation of NT-proBNP With or Without Elevation of cTnT", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Heart Failure With Preserved Ejection Fraction" ], "interventions": [ { "name": "mavacamten", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 30, "start_date": "2021-03-30", "completion_date": "2024-02-26", "has_results": true, "last_update_posted_date": "2025-03-20", "last_synced_at": "2026-10-22T00:31:12.816Z", "location_count": 20, "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 16 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04766892" }, { "nct_id": "NCT05879887", "title": "An Optimization Pilot to Optimize An Early Palliative Care Intervention for Advanced Heart Failure", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Chronic Illness", "Heart Failure - NYHA II - IV" ], "interventions": [ { "name": "UPHOLDS (Utilizing Palliative Care for Heart Failure Optimized using Lay Navigators to Decrease Suffering)", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Alabama at Birmingham", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 32, "start_date": "2024-08-15", "completion_date": "2026-08-01", "has_results": false, "last_update_posted_date": "2026-09-22", "last_synced_at": "2026-10-22T00:31:12.816Z", "location_count": 1, "location_summary": "Birmingham, Alabama", "locations": [ { "city": "Birmingham", "state": "Alabama" } ], "official_url": "https://clinicaltrials.gov/study/NCT05879887" } ] }