{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cardiac+Output%2C+Low",
    "query": {
      "condition": "Cardiac Output, Low"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 21,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cardiac+Output%2C+Low&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:07:31.942Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05905536",
      "title": "Perioperative Monitoring of Cardiac Surgery Patients With the Vitalstream Physiological Monitor",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiac Output, Low",
        "Stroke Volume"
      ],
      "interventions": [
        {
          "name": "Vitalstream",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 58,
      "start_date": "2023-08-15",
      "completion_date": "2024-07-30",
      "has_results": false,
      "last_update_posted_date": "2025-08-12",
      "last_synced_at": "2026-05-22T05:07:31.942Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05905536"
    },
    {
      "nct_id": "NCT02767024",
      "title": "Intravenous Vasodilator vs. Inotropic Therapy in Patients With Heart Failure",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Acute Heart Failure"
      ],
      "interventions": [
        {
          "name": "Sodium nitroprusside",
          "type": "DRUG"
        },
        {
          "name": "Dobutamine",
          "type": "DRUG"
        },
        {
          "name": "Furosemide",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2018-05-01",
      "completion_date": "2018-06-01",
      "has_results": false,
      "last_update_posted_date": "2018-10-31",
      "last_synced_at": "2026-05-22T05:07:31.942Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02767024"
    },
    {
      "nct_id": "NCT00027157",
      "title": "Determination of Variances in Exhaled Nitric Oxide Output in Normal Healthy Male Volunteers Consuming High and Low Nitrate/Nitrite Diets",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Healthy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "MALE",
        "summary": "Male only"
      },
      "enrollment_count": 18,
      "start_date": "2000-04",
      "completion_date": "2003-04",
      "has_results": false,
      "last_update_posted_date": "2008-03-04",
      "last_synced_at": "2026-05-22T05:07:31.942Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00027157"
    },
    {
      "nct_id": "NCT00590018",
      "title": "Corticosteroids in Postoperative Critically Ill Neonates With Low Cardiac Output Syndrome With Congenital Heart Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cardiac Output, Low"
      ],
      "interventions": [
        {
          "name": "Hydrocortisone",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Month",
        "sex": "ALL",
        "summary": "Up to 1 Month"
      },
      "enrollment_count": 18,
      "start_date": "2003-02",
      "completion_date": "2009-12",
      "has_results": true,
      "last_update_posted_date": "2016-05-26",
      "last_synced_at": "2026-05-22T05:07:31.942Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00590018"
    },
    {
      "nct_id": "NCT02511457",
      "title": "Comparison of Cardiac Output With LiDCO Rapid and TEE Against Thermodilution Technique in Cardiac Surgery",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Low Cardiac Output"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "30 Years to 90 Years"
      },
      "enrollment_count": 110,
      "start_date": "2012-10",
      "completion_date": "2015-08",
      "has_results": false,
      "last_update_posted_date": "2016-10-25",
      "last_synced_at": "2026-05-22T05:07:31.942Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02511457"
    },
    {
      "nct_id": "NCT06763549",
      "title": "COR-INSIGHT: Optimizing Cardiovascular and Cardiopulmonary Outcomes with AI-Driven Multiplexed Indications Using COR ECG Wearable",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiopulmonary Failure",
        "Myocardial Infarction (MI)",
        "Heart Decompensation",
        "Heart Failure",
        "HFrEF - Heart Failure with Reduced Ejection Fraction",
        "HFpEF - Heart Failure with Preserved Ejection Fraction",
        "Syncopation",
        "Syncope",
        "Ischemic Cardiovascular Disease",
        "STEMI",
        "STEMI (ST Elevation MI)",
        "Atrial Fibrillation (AF)",
        "Atrial Enlargement",
        "LVF",
        "Conduction Defect",
        "Conduction Abnormalities",
        "Heart Block",
        "Valvular Diseases",
        "Cardiac Output, Low",
        "Stroke Volume",
        "Stroke Volume Variation",
        "Hyperkalemia",
        "Hypercalcemia",
        "Hypocalcemia",
        "LV Dysfunction",
        "QT Prolongation",
        "Sudden Cardiac Death Due to Cardiac Arrhythmia",
        "Ventricular Arrhythmia",
        "Pacing",
        "Pacing Induced Dyssynchrony",
        "Silent Ischemia",
        "Pericarditis",
        "Sleep Related Breathing Disorder",
        "RSA",
        "Apnea, Obstructive",
        "Cardiac Output Measurement",
        "Respiratory Impedance",
        "CRT And/or ICD",
        "Infarction",
        "Cardiomyopathies, Primary",
        "Hypertrophy"
      ],
      "interventions": [
        {
          "name": "SUBPROTOCOL A",
          "type": "DEVICE"
        },
        {
          "name": "SUBPROTOCOL B",
          "type": "DEVICE"
        },
        {
          "name": "SUBPROTOCOL C",
          "type": "DEVICE"
        },
        {
          "name": "SUBPROTOCOL D",
          "type": "DEVICE"
        },
        {
          "name": "SUBPROTOCOL E",
          "type": "DEVICE"
        },
        {
          "name": "SUBPROTOCOL F",
          "type": "DEVICE"
        },
        {
          "name": "SUBPROTOCOL G",
          "type": "DEVICE"
        },
        {
          "name": "SUBPROTOCOL H",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Peerbridge Health, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15000,
      "start_date": "2024-11-16",
      "completion_date": "2026-04-15",
      "has_results": false,
      "last_update_posted_date": "2025-01-08",
      "last_synced_at": "2026-05-22T05:07:31.942Z",
      "location_count": 1,
      "location_summary": "Melbourne, Florida",
      "locations": [
        {
          "city": "Melbourne",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06763549"
    },
    {
      "nct_id": "NCT03016754",
      "title": "Heart Failure Optimization Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sudden Cardiac Death",
        "Sudden Cardiac Arrest",
        "Heart Failure",
        "Heart Failure Low Output"
      ],
      "interventions": [
        {
          "name": "Wearable Cardioverter Defibrillator",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zoll Medical Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 602,
      "start_date": "2017-03-01",
      "completion_date": "2022-06-01",
      "has_results": true,
      "last_update_posted_date": "2025-03-24",
      "last_synced_at": "2026-05-22T05:07:31.942Z",
      "location_count": 39,
      "location_summary": "Birmingham, Alabama • West Hills, California • Fernandina Beach, Florida + 34 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "West Hills",
          "state": "California"
        },
        {
          "city": "Fernandina Beach",
          "state": "Florida"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Jacksonville Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03016754"
    },
    {
      "nct_id": "NCT03869606",
      "title": "Non-Invasive Cardiac Output Monitor in Children",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiac Output, Low",
        "Pediatric"
      ],
      "interventions": [
        {
          "name": "NICOM by Cheetah Medical",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "11 Years to 17 Years"
      },
      "enrollment_count": 50,
      "start_date": "2019-04-01",
      "completion_date": "2020-04-01",
      "has_results": false,
      "last_update_posted_date": "2020-07-30",
      "last_synced_at": "2026-05-22T05:07:31.942Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03869606"
    },
    {
      "nct_id": "NCT02404597",
      "title": "Cardiac Output Monitoring in Burn Patients",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Burns"
      ],
      "interventions": [
        {
          "name": "NICOM (non-invasive cardiac output monitor)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2018-01",
      "completion_date": "2018-03",
      "has_results": false,
      "last_update_posted_date": "2018-02-28",
      "last_synced_at": "2026-05-22T05:07:31.942Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02404597"
    },
    {
      "nct_id": "NCT02025621",
      "title": "Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery On Cardiopulmonary Bypass",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Coronary Artery Bypass Grafting",
        "Mitral Valve Surgery",
        "Low Cardiac Output Syndrome"
      ],
      "interventions": [
        {
          "name": "Levosimendan",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tenax Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 882,
      "start_date": "2014-07",
      "completion_date": "2016-11",
      "has_results": true,
      "last_update_posted_date": "2018-06-21",
      "last_synced_at": "2026-05-22T05:07:31.942Z",
      "location_count": 49,
      "location_summary": "Burlington, Alabama • Huntsville, Alabama • Sacramento, California + 41 more",
      "locations": [
        {
          "city": "Burlington",
          "state": "Alabama"
        },
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02025621"
    }
  ]
}