{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cardiac+Valve+Annuloplasty",
    "query": {
      "condition": "Cardiac Valve Annuloplasty"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 16,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cardiac+Valve+Annuloplasty&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T04:42:20.914Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03016975",
      "title": "Edwards Cardioband System ACTIVE Pivotal Clinical Trial (ACTIVE)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Functional Mitral Regurgitation",
        "Mitral Regurgitation",
        "Mitral Insufficiency"
      ],
      "interventions": [
        {
          "name": "Edwards Cardioband System",
          "type": "DEVICE"
        },
        {
          "name": "Guideline Directed Medical Therapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Edwards Lifesciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2017-06-01",
      "completion_date": "2022-09-20",
      "has_results": true,
      "last_update_posted_date": "2023-11-30",
      "last_synced_at": "2026-07-24T04:42:20.914Z",
      "location_count": 24,
      "location_summary": "Los Angeles, California • Palo Alto, California • Aurora, Colorado + 18 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03016975"
    },
    {
      "nct_id": "NCT06951672",
      "title": "AMEND TS Early Feasibility Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Symptomatic Functional MR 3 or Greater"
      ],
      "interventions": [
        {
          "name": "This study will evaluate the safety and functionality of the AMEND™ Trans-Septal System for annuloplasty as a therapy for mitral regurgitation.",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Valcare Medical Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2025-09-11",
      "completion_date": "2027-04",
      "has_results": false,
      "last_update_posted_date": "2026-01-07",
      "last_synced_at": "2026-07-24T04:42:20.914Z",
      "location_count": 11,
      "location_summary": "Phoenix, Arizona • La Jolla, California • Atlanta, Georgia + 8 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06951672"
    },
    {
      "nct_id": "NCT04067635",
      "title": "Primary Mitral Regurgitation Repair",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mitral Valve Insufficiency",
        "Mitral Valve Prolapse",
        "Chronic Mitral Disease",
        "Mitral Regurgitation",
        "Mitral Valve Disease",
        "Degenerative Mitral Valve Disease",
        "Myxomatous Mitral Valve Degeneration",
        "Ventricular Remodeling"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Eric Y. Yang, MD PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 116,
      "start_date": "2018-05-25",
      "completion_date": "2021-06",
      "has_results": false,
      "last_update_posted_date": "2019-08-28",
      "last_synced_at": "2026-07-24T04:42:20.914Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04067635"
    },
    {
      "nct_id": "NCT01585779",
      "title": "Contour 3D®/TriAd® Tricuspid Annuloplasty Ring Post-Market Clinical Trial",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Tricuspid Valve Regurgitation",
        "Tricuspid Valve Insufficiency"
      ],
      "interventions": [
        {
          "name": "Contour 3D® implant for tricuspid valve repair",
          "type": "DEVICE"
        },
        {
          "name": "Tri-Ad® implant for tricuspid valve repair",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic Cardiovascular",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 64,
      "start_date": "2012-05",
      "completion_date": "2016-06",
      "has_results": true,
      "last_update_posted_date": "2017-05-10",
      "last_synced_at": "2026-07-24T04:42:20.914Z",
      "location_count": 3,
      "location_summary": "Aventura, Florida • Ann Arbor, Michigan • Asheville, North Carolina",
      "locations": [
        {
          "city": "Aventura",
          "state": "Florida"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Asheville",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01585779"
    },
    {
      "nct_id": "NCT06479824",
      "title": "NHLBI and Cook Trans-Atrial Intra-Pericardial Tricuspid Annuloplasty (TRAIPTA) Early Feasibility Study",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tricuspid Valve Insufficiency"
      ],
      "interventions": [
        {
          "name": "TRAIPTA (Trans-Atrial Intra-Pericardial Tricuspid Annuloplasty)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "21 Years to 100 Years"
      },
      "enrollment_count": 60,
      "start_date": "2025-08-19",
      "completion_date": "2030-09-01",
      "has_results": false,
      "last_update_posted_date": "2026-06-17",
      "last_synced_at": "2026-07-24T04:42:20.914Z",
      "location_count": 2,
      "location_summary": "Atlanta, Georgia • Roslyn, New York",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Roslyn",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06479824"
    },
    {
      "nct_id": "NCT04785885",
      "title": "Assessment of Clinical Onset of IV Heparin in Interventional Cardiology and Cardiac Surgery",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Transcatheter Aortic Valve Replacement",
        "Cardiac Valve Annuloplasty"
      ],
      "interventions": [
        {
          "name": "iStat Handheld Blood Analyzer",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Hemochron",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Rhode Island Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 40,
      "start_date": "2021-03-09",
      "completion_date": "2022-04-30",
      "has_results": false,
      "last_update_posted_date": "2021-09-29",
      "last_synced_at": "2026-07-24T04:42:20.914Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04785885"
    },
    {
      "nct_id": "NCT01246947",
      "title": "Tricuspid Annuloplasty for Moderate Tricuspid Regurgitation Associated With Miral Operation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiac Surgery",
        "Tricuspid Valve Regurgitation"
      ],
      "interventions": [
        {
          "name": "Tricuspid valve repair",
          "type": "PROCEDURE"
        },
        {
          "name": "Mitral surgery alone",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 57,
      "start_date": "2010-09",
      "completion_date": "2017-02",
      "has_results": false,
      "last_update_posted_date": "2023-05-08",
      "last_synced_at": "2026-07-24T04:42:20.914Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01246947"
    },
    {
      "nct_id": "NCT06965725",
      "title": "Paired-Ring Mitral Annuloplasty Ring Sizing Device",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Valve Diseases"
      ],
      "interventions": [
        {
          "name": "Annuloplasy ring sizing device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Endeavor Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2025-07-03",
      "completion_date": "2026-11",
      "has_results": false,
      "last_update_posted_date": "2025-07-15",
      "last_synced_at": "2026-07-24T04:42:20.914Z",
      "location_count": 1,
      "location_summary": "Glenview, Illinois",
      "locations": [
        {
          "city": "Glenview",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06965725"
    },
    {
      "nct_id": "NCT00428103",
      "title": "Effects of Mitral Valve Repair With the Geoform Ring on Cardiomyopathy",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mitral Valve Regurgitation",
        "Congestive Heart Failure",
        "Cardiomyopathy"
      ],
      "interventions": [
        {
          "name": "3 dimensional echocardiography",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Juan Crestanello, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2006-10",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2013-02-28",
      "last_synced_at": "2026-07-24T04:42:20.914Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00428103"
    },
    {
      "nct_id": "NCT00567853",
      "title": "Safety and Efficacy Study of the Sorin 3D Annuloplasty Ring For Mitral Repair",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Mitral Valve Regurgitation"
      ],
      "interventions": [
        {
          "name": "Implantation of the MEMO 3D Annuloplasty Ring",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sorin Group USA, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 278,
      "start_date": "2007-08",
      "completion_date": "2013-06",
      "has_results": false,
      "last_update_posted_date": "2015-01-26",
      "last_synced_at": "2026-07-24T04:42:20.914Z",
      "location_count": 4,
      "location_summary": "Minneapolis, Minnesota • St Louis, Missouri • Philadelphia, Pennsylvania + 1 more",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Plano",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00567853"
    }
  ]
}