{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cardiac+Valve+Surgery&page=2",
    "query": {
      "condition": "Cardiac Valve Surgery",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cardiac+Valve+Surgery&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T10:10:40.981Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02025621",
      "title": "Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing Cardiac Surgery On Cardiopulmonary Bypass",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Coronary Artery Bypass Grafting",
        "Mitral Valve Surgery",
        "Low Cardiac Output Syndrome"
      ],
      "interventions": [
        {
          "name": "Levosimendan",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tenax Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 882,
      "start_date": "2014-07",
      "completion_date": "2016-11",
      "has_results": true,
      "last_update_posted_date": "2018-06-21",
      "last_synced_at": "2026-07-23T10:10:40.981Z",
      "location_count": 49,
      "location_summary": "Burlington, Alabama • Huntsville, Alabama • Sacramento, California + 41 more",
      "locations": [
        {
          "city": "Burlington",
          "state": "Alabama"
        },
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02025621"
    },
    {
      "nct_id": "NCT03635424",
      "title": "Medtronic Transcatheter Aortic Valve Replacement (TAVR) Low Risk Bicuspid Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bicuspid Aortic Valve"
      ],
      "interventions": [
        {
          "name": "Medtronic TAVR Systems",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic Cardiovascular",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2018-10-30",
      "completion_date": "2030-12",
      "has_results": true,
      "last_update_posted_date": "2026-05-05",
      "last_synced_at": "2026-07-23T10:10:40.981Z",
      "location_count": 25,
      "location_summary": "Phoenix, Arizona • La Jolla, California • Thousand Oaks, California + 21 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Thousand Oaks",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Clearwater",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03635424"
    },
    {
      "nct_id": "NCT05206929",
      "title": "Prescribed Sternal Precautions vs. Self-Guided Restrictive Care (PEEERC)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Surgery",
        "Heart Diseases",
        "Heart Failure",
        "Cardiac Valve Disease"
      ],
      "interventions": [
        {
          "name": "Self Managed Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 10,
      "start_date": "2021-06-01",
      "completion_date": "2025-10-30",
      "has_results": false,
      "last_update_posted_date": "2025-11-10",
      "last_synced_at": "2026-07-23T10:10:40.981Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05206929"
    },
    {
      "nct_id": "NCT01187329",
      "title": "The Effect of the Hyperinsulinemic Normoglycemic Clamp on Myocardial Function and Utilization of Glucose",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hyperglycemia",
        "Aortic Valve Replacement",
        "Aortic Stenosis",
        "Cardiac Surgery"
      ],
      "interventions": [
        {
          "name": "hyperinsulinemic normoglycemic clamp (HNC)",
          "type": "OTHER"
        },
        {
          "name": "control group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "40 Years to 84 Years"
      },
      "enrollment_count": 100,
      "start_date": "2010-10",
      "completion_date": "2013-12",
      "has_results": true,
      "last_update_posted_date": "2018-11-20",
      "last_synced_at": "2026-07-23T10:10:40.981Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01187329"
    },
    {
      "nct_id": "NCT07466745",
      "title": "Autus Valve Continued Access Study (CAS)",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Congenital Heart Disease"
      ],
      "interventions": [
        {
          "name": "Pulmonary Valve Replacement Surgery",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Edwards Lifesciences",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Months",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "18 Months to 16 Years"
      },
      "enrollment_count": 36,
      "start_date": "2026-07-30",
      "completion_date": "2036-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-07-17",
      "last_synced_at": "2026-07-23T10:10:40.981Z",
      "location_count": 10,
      "location_summary": "Los Angeles, California • Aurora, Colorado • Atlanta, Georgia + 7 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07466745"
    },
    {
      "nct_id": "NCT00226265",
      "title": "The Short Form-36: Pre- Versus Post-Surgical Administration in Cardiac Surgery Patients",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Coronary Artery Bypass Grafting",
        "Heart Diseases",
        "Heart Valve Diseases"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 50,
      "start_date": "1999-01",
      "completion_date": "2007-09",
      "has_results": false,
      "last_update_posted_date": "2017-02-23",
      "last_synced_at": "2026-07-23T10:10:40.981Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00226265"
    },
    {
      "nct_id": "NCT06030115",
      "title": "Effects of a Hybrid Model of Cardiac Rehabilitation on Patient Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiac Surgery",
        "Coronary Artery Bypass Graft CABG",
        "Stent",
        "Valve Replacement"
      ],
      "interventions": [
        {
          "name": "Exercise Component Of Cardiac Rehabilitation (Hybrid Model) Intensity Recovery Progression Protocol (IRPP)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Good Shepherd Integrated Healthcare Systems",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 100,
      "start_date": "2019-07-01",
      "completion_date": "2021-07-31",
      "has_results": false,
      "last_update_posted_date": "2023-09-08",
      "last_synced_at": "2026-07-23T10:10:40.981Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06030115"
    },
    {
      "nct_id": "NCT02701283",
      "title": "Medtronic Evolut Transcatheter Aortic Valve Replacement in Low Risk Patients",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Valve Stenosis"
      ],
      "interventions": [
        {
          "name": "Medtronic Transcatheter Aortic Valve Replacement Systems",
          "type": "DEVICE"
        },
        {
          "name": "Surgical Aortic Valve Replacement (SAVR)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic Cardiovascular",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 2223,
      "start_date": "2016-03",
      "completion_date": "2029-06",
      "has_results": true,
      "last_update_posted_date": "2026-05-07",
      "last_synced_at": "2026-07-23T10:10:40.981Z",
      "location_count": 61,
      "location_summary": "Phoenix, Arizona • La Jolla, California • Los Angeles, California + 53 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Mountain View",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02701283"
    },
    {
      "nct_id": "NCT00567853",
      "title": "Safety and Efficacy Study of the Sorin 3D Annuloplasty Ring For Mitral Repair",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Mitral Valve Regurgitation"
      ],
      "interventions": [
        {
          "name": "Implantation of the MEMO 3D Annuloplasty Ring",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sorin Group USA, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 278,
      "start_date": "2007-08",
      "completion_date": "2013-06",
      "has_results": false,
      "last_update_posted_date": "2015-01-26",
      "last_synced_at": "2026-07-23T10:10:40.981Z",
      "location_count": 4,
      "location_summary": "Minneapolis, Minnesota • St Louis, Missouri • Philadelphia, Pennsylvania + 1 more",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Plano",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00567853"
    },
    {
      "nct_id": "NCT02675244",
      "title": "Evaluating the Benefit of Concurrent Tricuspid Valve Repair During Mitral Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mild Tricuspid Regurgitation",
        "Moderate Tricuspid Regurgitation",
        "Tricuspid Regurgitation"
      ],
      "interventions": [
        {
          "name": "TV Annuloplasty",
          "type": "PROCEDURE"
        },
        {
          "name": "MVS",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 401,
      "start_date": "2016-05-26",
      "completion_date": "2021-04-19",
      "has_results": true,
      "last_update_posted_date": "2024-06-18",
      "last_synced_at": "2026-07-23T10:10:40.981Z",
      "location_count": 24,
      "location_summary": "Los Angeles, California • Stanford, California • New Haven, Connecticut + 20 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02675244"
    }
  ]
}