{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Caries%2CDental",
    "query": {
      "condition": "Caries,Dental"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 210,
    "total_pages": 21,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Caries%2CDental&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T13:13:17.712Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03716349",
      "title": "Esthetics of Dental Composite and Adhesive System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cavities of Teeth"
      ],
      "interventions": [
        {
          "name": "Pulp vitality testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Photos",
          "type": "OTHER"
        },
        {
          "name": "local and/or topical anesthetic",
          "type": "DRUG"
        },
        {
          "name": "rubber dam",
          "type": "DEVICE"
        },
        {
          "name": "tooth surface cleaned",
          "type": "OTHER"
        },
        {
          "name": "enamel margins",
          "type": "PROCEDURE"
        },
        {
          "name": "Adhesive Systems",
          "type": "PROCEDURE"
        },
        {
          "name": "cavity preparation",
          "type": "PROCEDURE"
        },
        {
          "name": "Shade selection using Easy Shade 5",
          "type": "OTHER"
        },
        {
          "name": "Light Curing",
          "type": "PROCEDURE"
        },
        {
          "name": "Contoured and polished",
          "type": "PROCEDURE"
        },
        {
          "name": "Consent",
          "type": "OTHER"
        },
        {
          "name": "Health Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "xray",
          "type": "RADIATION"
        },
        {
          "name": "Release of medical information signed",
          "type": "OTHER"
        },
        {
          "name": "Oral Exam",
          "type": "OTHER"
        },
        {
          "name": "Teeth Assessment",
          "type": "OTHER"
        },
        {
          "name": "Clinical Assessment",
          "type": "OTHER"
        },
        {
          "name": "Tokuyama Universal Bond",
          "type": "DEVICE"
        },
        {
          "name": "ScotchBond",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "OTHER",
        "DRUG",
        "DEVICE",
        "PROCEDURE",
        "RADIATION"
      ],
      "sponsor": "Erica Teixeira",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2019-01-01",
      "completion_date": "2025-11-20",
      "has_results": true,
      "last_update_posted_date": "2026-05-01",
      "last_synced_at": "2026-06-10T13:13:17.712Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03716349"
    },
    {
      "nct_id": "NCT00490165",
      "title": "Periodontal and Periapical Inflammation and Pregnancy",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Periodontal Disease",
        "Periapical Disease",
        "Pregnancy",
        "Diabetes",
        "Cardiovascular Disease",
        "Dental Caries"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Roger Johnson",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "10 Years and older · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2007-03",
      "completion_date": "2011-12",
      "has_results": false,
      "last_update_posted_date": "2012-04-06",
      "last_synced_at": "2026-06-10T13:13:17.712Z",
      "location_count": 1,
      "location_summary": "Jackson, Mississippi",
      "locations": [
        {
          "city": "Jackson",
          "state": "Mississippi"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00490165"
    },
    {
      "nct_id": "NCT02635867",
      "title": "Clinical Comparison of Vital Pulp Capping Restorative Protocols",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Deep Dental Caries"
      ],
      "interventions": [
        {
          "name": "Indirect Pulp capping-Resin-modified calcium silicate - TheraCal",
          "type": "PROCEDURE"
        },
        {
          "name": "Indirect Pulp capping-Calcium hydroxide - Dycal",
          "type": "PROCEDURE"
        },
        {
          "name": "Indirect Pulp capping-Resin-based dentin bonding agent",
          "type": "PROCEDURE"
        },
        {
          "name": "Direct Pulp capping-Resin-modified calcium silicate - TheraCal",
          "type": "PROCEDURE"
        },
        {
          "name": "Direct Pulp capping-Calcium hydroxide - Dycal",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 109,
      "start_date": "2015-06",
      "completion_date": "2019-08",
      "has_results": true,
      "last_update_posted_date": "2023-10-12",
      "last_synced_at": "2026-06-10T13:13:17.712Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02635867"
    },
    {
      "nct_id": "NCT00393055",
      "title": "Xylitol Adult Caries Trial (X-ACT)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "xylitol",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "inactive lozenge",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "25 Years to 80 Years"
      },
      "enrollment_count": 709,
      "start_date": "2007-01",
      "completion_date": "2011-06",
      "has_results": false,
      "last_update_posted_date": "2011-09-12",
      "last_synced_at": "2026-06-10T13:13:17.712Z",
      "location_count": 3,
      "location_summary": "Birmingham, Alabama • Chapel Hill, North Carolina • San Antonio, Texas",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00393055"
    },
    {
      "nct_id": "NCT03916926",
      "title": "Older Adult Effectiveness of 2 Treatments",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "A \"simple medical strategy\" consisting of silver diamine fluoride (SDF)",
          "type": "DEVICE"
        },
        {
          "name": "B \"typical dental strategy\" consisting of atraumatic restorative treatment (ART) with glass ionomer cement + Fluoride varnish (FV)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Case Western Reserve University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "62 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "62 Years and older"
      },
      "enrollment_count": 568,
      "start_date": "2019-09-18",
      "completion_date": "2024-06-07",
      "has_results": true,
      "last_update_posted_date": "2025-08-13",
      "last_synced_at": "2026-06-10T13:13:17.712Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03916926"
    },
    {
      "nct_id": "NCT01286259",
      "title": "Short-term Disulfiram Administration to Accelerate the Decay of the HIV Reservoir in Antiretroviral-treated HIV Infected Individuals",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV-1 Infection"
      ],
      "interventions": [
        {
          "name": "Disulfiram",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 16,
      "start_date": "2011-01",
      "completion_date": "2014-05",
      "has_results": true,
      "last_update_posted_date": "2020-06-30",
      "last_synced_at": "2026-06-10T13:13:17.712Z",
      "location_count": 2,
      "location_summary": "San Francisco, California • Baltimore, Maryland",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01286259"
    },
    {
      "nct_id": "NCT06714929",
      "title": "Advancing Water Security: A Community Participatory School-Based Hydration Intervention",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries",
        "Obesity Prevention"
      ],
      "interventions": [
        {
          "name": "Hydration",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "4 Years and older"
      },
      "enrollment_count": 7200,
      "start_date": "2024-08-14",
      "completion_date": "2028-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-06-11",
      "last_synced_at": "2026-06-10T13:13:17.712Z",
      "location_count": 1,
      "location_summary": "Henrico, Virginia",
      "locations": [
        {
          "city": "Henrico",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06714929"
    },
    {
      "nct_id": "NCT06182267",
      "title": "Maximal Use Study to Determine the Pharmacokinetics of L-arginine After Exaggerated Oral Use of COL101",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Caries,Dental"
      ],
      "interventions": [
        {
          "name": "L Arginine",
          "type": "DRUG"
        },
        {
          "name": "Sodium Fluoride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Colgate Palmolive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 29,
      "start_date": "2023-11-27",
      "completion_date": "2023-12-22",
      "has_results": false,
      "last_update_posted_date": "2024-01-02",
      "last_synced_at": "2026-06-10T13:13:17.712Z",
      "location_count": 1,
      "location_summary": "Fair Lawn, New Jersey",
      "locations": [
        {
          "city": "Fair Lawn",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06182267"
    },
    {
      "nct_id": "NCT04822233",
      "title": "A Comparative Study of Hall Technique, Modified Hall Technique and Conventional Stainless-Steel Crown Restorations in the Treatment of Primary Molars With Proximal Caries Lesions.",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Hall Technique (HT)",
          "type": "DEVICE"
        },
        {
          "name": "Modified Hall Technique (MHT)",
          "type": "DEVICE"
        },
        {
          "name": "Conventional Technique (CT)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "8 Years",
        "sex": "ALL",
        "summary": "5 Years to 8 Years"
      },
      "enrollment_count": 132,
      "start_date": "2023-06-01",
      "completion_date": "2025-12-01",
      "has_results": false,
      "last_update_posted_date": "2023-05-19",
      "last_synced_at": "2026-06-10T13:13:17.712Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04822233"
    },
    {
      "nct_id": "NCT03032705",
      "title": "Clinical Evaluation of Kerr SonicFill™ 2 vs 3M ESPE Filtek™ Supreme Ultra Universal Restorative",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "SonicFill™ 2",
          "type": "DEVICE"
        },
        {
          "name": "Filtek™ Supreme",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 51,
      "start_date": "2017-06-19",
      "completion_date": "2020-02-05",
      "has_results": true,
      "last_update_posted_date": "2021-12-13",
      "last_synced_at": "2026-06-10T13:13:17.712Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03032705"
    }
  ]
}