{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cartilage+Injury",
    "query": {
      "condition": "Cartilage Injury"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 49,
    "total_pages": 5,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Cartilage+Injury&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T00:07:00.006Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06916728",
      "title": "A Post Approval Multicenter 10 Year Follow-up Observational Trial of Marketed Product - MP01 vs. Surgical Standard of Care (SSOC) Used for the Treatment of Joint Surface Lesions of the Knee",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Knee Injuries",
        "Joint Surface Knee Lesions"
      ],
      "interventions": [
        {
          "name": "Marketed Product - MP01",
          "type": "DEVICE"
        },
        {
          "name": "Surgical Standard of Care",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Smith & Nephew, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 170,
      "start_date": "2025-05-05",
      "completion_date": "2030-02-04",
      "has_results": false,
      "last_update_posted_date": "2026-07-16",
      "last_synced_at": "2026-07-22T00:07:00.006Z",
      "location_count": 1,
      "location_summary": "La Mesa, California",
      "locations": [
        {
          "city": "La Mesa",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06916728"
    },
    {
      "nct_id": "NCT02648971",
      "title": "Controlled Trial to Compare Single Versus Two Portal Knee Arthroscopy Techniques",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Injuries, Knee"
      ],
      "interventions": [
        {
          "name": "Single Portal Knee Arthroscopy",
          "type": "PROCEDURE"
        },
        {
          "name": "Two Portal Knee Arthroscopy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 36,
      "start_date": "2016-01",
      "completion_date": "2018-05-31",
      "has_results": true,
      "last_update_posted_date": "2020-12-30",
      "last_synced_at": "2026-07-22T00:07:00.006Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02648971"
    },
    {
      "nct_id": "NCT06792539",
      "title": "Evaluate the Safety and Effectiveness of the Polymotion Hip Resurfacing (PHR) System Compared to Total Hip Arthroplasty",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis of the Hip",
        "Degenerative Joint Disease of Hip",
        "Dysplasia; Hip"
      ],
      "interventions": [
        {
          "name": "Polymotion Hip Resurfacing (PHR) System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "JointMedica Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 238,
      "start_date": "2025-01-22",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2026-05-01",
      "last_synced_at": "2026-07-22T00:07:00.006Z",
      "location_count": 8,
      "location_summary": "Tampa, Florida • Chicago, Illinois • Baltimore, Maryland + 5 more",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New Albany",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06792539"
    },
    {
      "nct_id": "NCT04118023",
      "title": "7T MRI to Evaluate Cartilage Defects in the Knee",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cartilage Injury",
        "Knee Injuries",
        "Arthropathy of Knee",
        "Cartilage Damage",
        "Knee Pain Swelling"
      ],
      "interventions": [
        {
          "name": "7 Tesla Magnetic Resonance Imaging Test",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "The Methodist Hospital Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 112,
      "start_date": "2019-10-07",
      "completion_date": "2022-09-07",
      "has_results": false,
      "last_update_posted_date": "2025-02-07",
      "last_synced_at": "2026-07-22T00:07:00.006Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04118023"
    },
    {
      "nct_id": "NCT04739930",
      "title": "Autologous Bone Marrow Concentrate in Knee Osteochondral Allograft Transplantation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cartilage Injury"
      ],
      "interventions": [
        {
          "name": "Autologous bone marrow aspirate will be harvested and concentrated to a bone marrow aspirate concentrate (BMAC) containing bone marrow derived mesenchymal stem cells and delivered to site of operation",
          "type": "PROCEDURE"
        },
        {
          "name": "Control group incision",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 33,
      "start_date": "2018-03-02",
      "completion_date": "2023-01-12",
      "has_results": false,
      "last_update_posted_date": "2023-01-13",
      "last_synced_at": "2026-07-22T00:07:00.006Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04739930"
    },
    {
      "nct_id": "NCT03101163",
      "title": "Efficacy and Safety Study of Intra-Articular Injections of Autologous Peripheral Blood Stem Cells Following Subchondral Drilling Surgery for the Treatment of Articular Cartilage Injury in the Knee",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Articular Cartilage Disorder of Knee",
        "Articular Cartilage; Degeneration"
      ],
      "interventions": [
        {
          "name": "Autologous peripheral blood stem cells and hyaluronic acid",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Hyaluronic acid",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "KLSMC Stem Cells, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 120,
      "start_date": "2015-12",
      "completion_date": "2022-07",
      "has_results": false,
      "last_update_posted_date": "2022-08-16",
      "last_synced_at": "2026-07-22T00:07:00.006Z",
      "location_count": 1,
      "location_summary": "Gulf Breeze, Florida",
      "locations": [
        {
          "city": "Gulf Breeze",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03101163"
    },
    {
      "nct_id": "NCT04135950",
      "title": "Prospective Registry of Anterior Cruciate Ligament Reconstructions",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Anterior Cruciate Ligament Tear",
        "Meniscal Tear",
        "Cartilage Injury",
        "Bone Bruising"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "State University of New York at Buffalo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1646,
      "start_date": "2005-01",
      "completion_date": "2025-10-28",
      "has_results": false,
      "last_update_posted_date": "2025-11-20",
      "last_synced_at": "2026-07-22T00:07:00.006Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04135950"
    },
    {
      "nct_id": "NCT00821873",
      "title": "Evaluation of the CR Plug for Repair of Defects Created at the Harvest Site From an Autograft in the Knee.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Knee Injury"
      ],
      "interventions": [
        {
          "name": "CR Plug",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "RTI Surgical",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 9,
      "start_date": "2008-12",
      "completion_date": "2012-07",
      "has_results": true,
      "last_update_posted_date": "2013-11-28",
      "last_synced_at": "2026-07-22T00:07:00.006Z",
      "location_count": 4,
      "location_summary": "Birmingham, Alabama • Phoenix, Arizona • Englewood, Colorado + 1 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Englewood",
          "state": "Colorado"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00821873"
    },
    {
      "nct_id": "NCT05007366",
      "title": "Optimizing Gait Biomechanics for Posttraumatic Osteoarthritis Prevention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Injuries",
        "Post-traumatic Osteoarthritis",
        "Knee Osteoarthritis",
        "Knee Injuries",
        "Cartilage, Articular",
        "Gait"
      ],
      "interventions": [
        {
          "name": "Real-time gait biofeedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham real-time gait biofeedback",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 24,
      "start_date": "2021-08-05",
      "completion_date": "2022-12-02",
      "has_results": false,
      "last_update_posted_date": "2023-04-18",
      "last_synced_at": "2026-07-22T00:07:00.006Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05007366"
    },
    {
      "nct_id": "NCT04906499",
      "title": "Preventing Posttraumatic Osteoarthritis With Physical Activity Promotion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Injuries",
        "Exercise",
        "Cartilage, Articular",
        "Knee Injuries",
        "Osteoarthritis",
        "Osteoarthritis, Knee",
        "Arthritis",
        "Joint Diseases"
      ],
      "interventions": [
        {
          "name": "Physical Activity Promotion",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 7,
      "start_date": "2021-08-01",
      "completion_date": "2022-09-09",
      "has_results": true,
      "last_update_posted_date": "2024-01-29",
      "last_synced_at": "2026-07-22T00:07:00.006Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04906499"
    }
  ]
}