{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Castleman%27s+Disease+%28CD%29", "query": { "condition": "Castleman's Disease (CD)" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 6, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-05-22T01:45:24.750Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02871050", "title": "Castleman Disease Collaborative Network Biobank", "overall_status": "WITHDRAWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Castleman Disease", "Castleman's Disease", "Giant Lymph Node Hyperplasia", "Angiofollicular Lymph Hyperplasia", "Angiofollicular Lymph Node Hyperplasia", "Angiofollicular Lymphoid Hyperplasia", "GLNH", "Hyperplasia", "Giant Lymph Node" ], "interventions": [ { "name": "Sample Collection", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Castleman Disease Collaborative Network", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 0, "start_date": "2016-06", "completion_date": "2018-06", "has_results": false, "last_update_posted_date": "2018-07-31", "last_synced_at": "2026-05-22T01:45:24.750Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02871050" }, { "nct_id": "NCT02853968", "title": "Unlock the Cell: Castleman's Disease Flow Cytometry Study", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Castleman Disease", "Angiofollicular Lymphoid Hyperplasia", "GLNH", "Hyperplasia", "Castleman's Disease", "Angiofollicular Lymph Hyperplasia", "Giant Lymph Node Hyperplasia" ], "interventions": [ { "name": "Blood draw/buccal swab", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 130, "start_date": "2016-02", "completion_date": "2019-03-30", "has_results": false, "last_update_posted_date": "2020-03-26", "last_synced_at": "2026-05-22T01:45:24.750Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02853968" }, { "nct_id": "NCT07085039", "title": "Ruxolitinib in Previously Treated Idiopathic Multicentric Castleman Disease", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Castleman's Disease (CD)", "Idiopathic Multicentric Castleman's Disease" ], "interventions": [ { "name": "Ruxolitinib", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 14, "start_date": "2025-12-18", "completion_date": "2028-12-31", "has_results": false, "last_update_posted_date": "2026-04-22", "last_synced_at": "2026-05-22T01:45:24.750Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT07085039" }, { "nct_id": "NCT05028621", "title": "Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms and Castleman Disease", "overall_status": "SUSPENDED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Castleman's Disease (CD)", "Langerhans Cell Histiocytosis (LCH)", "Non-Langerhans-Cell Histiocytosis" ], "interventions": [ { "name": "Genetic testing", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Case Comprehensive Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 135, "start_date": "2021-06-18", "completion_date": "2026-09", "has_results": false, "last_update_posted_date": "2026-05-07", "last_synced_at": "2026-05-22T01:45:24.750Z", "location_count": 1, "location_summary": "Cleveland, Ohio", "locations": [ { "city": "Cleveland", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT05028621" }, { "nct_id": "NCT03933904", "title": "Sirolimus in Previously Treated Idiopathic Multicentric Castleman Disease", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Castleman Disease", "Castleman's Disease, Multicentric" ], "interventions": [ { "name": "Sirolimus", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "2 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "2 Years to 80 Years" }, "enrollment_count": 7, "start_date": "2019-09-25", "completion_date": "2026-06-30", "has_results": true, "last_update_posted_date": "2026-03-03", "last_synced_at": "2026-05-22T01:45:24.750Z", "location_count": 2, "location_summary": "Little Rock, Arkansas • Philadelphia, Pennsylvania", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT03933904" }, { "nct_id": "NCT02817997", "title": "International Registry for Patients With Castleman Disease", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Castleman Disease", "Castleman's Disease", "Giant Lymph Node Hyperplasia", "Angiofollicular Lymph Hyperplasia", "Angiofollicular Lymph Node Hyperplasia", "Angiofollicular Lymphoid Hyperplasia", "GLNH", "Hyperplasia, Giant Lymph Node", "Lymph Node Hyperplasia, Giant" ], "interventions": [], "intervention_types": [], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 1000, "start_date": "2016-10", "completion_date": "2027-09", "has_results": false, "last_update_posted_date": "2026-03-03", "last_synced_at": "2026-05-22T01:45:24.750Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02817997" } ] }