{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Central+Line+Infection&page=2",
    "query": {
      "condition": "Central Line Infection",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Central+Line+Infection&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T01:34:21.780Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02227329",
      "title": "Prophylactic Ethanol Lock Therapy (ELT) in Patients on Home Parenteral Nutrition",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Catheter-related Bloodstream Infection (CRBSI) Nos",
        "Bloodstream Infection Due to Central Venous Catheter",
        "Bloodstream Infection Due to Hickman Catheter"
      ],
      "interventions": [
        {
          "name": "Ethanol",
          "type": "DRUG"
        },
        {
          "name": "Heparin Lock",
          "type": "DRUG"
        },
        {
          "name": "Normal Saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 39,
      "start_date": "2014-07",
      "completion_date": "2016-10",
      "has_results": true,
      "last_update_posted_date": "2017-12-12",
      "last_synced_at": "2026-06-11T01:34:21.780Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02227329"
    },
    {
      "nct_id": "NCT01817075",
      "title": "Chlorhexidine Gluconate Cleansing in Preventing Central Line Associated Bloodstream Infection and Acquisition of Multi-drug Resistant Organisms in Younger Patients With Cancer or Undergoing Donor Stem Cell Transplant",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Bacterial Infection",
        "Benign Neoplasm",
        "Malignant Neoplasm",
        "Methicillin-Resistant Staphylococcus Aureus Infection",
        "Myeloid Neoplasm",
        "Recurrent Childhood Acute Lymphoblastic Leukemia",
        "Recurrent Childhood Acute Myeloid Leukemia"
      ],
      "interventions": [
        {
          "name": "Chlorhexidine Gluconate Skin Cleanser",
          "type": "PROCEDURE"
        },
        {
          "name": "Laboratory Biomarker Analysis",
          "type": "OTHER"
        },
        {
          "name": "Mild Soap Skin Cleanser",
          "type": "PROCEDURE"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Children's Oncology Group",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Months",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "2 Months to 21 Years"
      },
      "enrollment_count": 177,
      "start_date": "2013-11-04",
      "completion_date": "2020-03-31",
      "has_results": true,
      "last_update_posted_date": "2021-06-22",
      "last_synced_at": "2026-06-11T01:34:21.780Z",
      "location_count": 53,
      "location_summary": "Duarte, California • Long Beach, California • Los Angeles, California + 44 more",
      "locations": [
        {
          "city": "Duarte",
          "state": "California"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Madera",
          "state": "California"
        },
        {
          "city": "Oakland",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01817075"
    },
    {
      "nct_id": "NCT01893060",
      "title": "Umbilical Cord Care for the Prevention of Colonization",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Line Insertion Site",
        "Central Line-associated Bloodstream Infection (CLABSI)"
      ],
      "interventions": [
        {
          "name": "Povidone-Iodine",
          "type": "DRUG"
        },
        {
          "name": "Chlorhexidine gluconate",
          "type": "DRUG"
        },
        {
          "name": "Pluronic Cream",
          "type": "DRUG"
        },
        {
          "name": "control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "7 Days",
        "sex": "ALL",
        "summary": "Up to 7 Days"
      },
      "enrollment_count": 100,
      "start_date": "2013-07",
      "completion_date": "2014-07",
      "has_results": false,
      "last_update_posted_date": "2013-08-02",
      "last_synced_at": "2026-06-11T01:34:21.780Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01893060"
    },
    {
      "nct_id": "NCT01165411",
      "title": "Developing and Maintaining a Central Venous Catheter Registry",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Infection"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Lehigh Valley Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 4530,
      "start_date": "2008-08",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2016-10-14",
      "last_synced_at": "2026-06-11T01:34:21.780Z",
      "location_count": 1,
      "location_summary": "Allentown, Pennsylvania",
      "locations": [
        {
          "city": "Allentown",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01165411"
    },
    {
      "nct_id": "NCT02890875",
      "title": "Efficacy and Safety of Ethanol Lock Therapy for the Prevention of Central Line-associated Bloodstream Infections",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Catheter-Related Infections"
      ],
      "interventions": [
        {
          "name": "Ethanol lock",
          "type": "OTHER"
        },
        {
          "name": "Heparin lock",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 3,
      "start_date": "2016-08",
      "completion_date": "2017-03",
      "has_results": false,
      "last_update_posted_date": "2019-05-02",
      "last_synced_at": "2026-06-11T01:34:21.780Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02890875"
    },
    {
      "nct_id": "NCT05228132",
      "title": "The Pristine Post-Market Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Kidney Failure, Chronic",
        "Hemodialysis Complication",
        "Hemodialysis Catheter Infection",
        "Hemodialysis Access Failure",
        "Central Venous Catheter Related Bloodstream Infection",
        "End Stage Renal Disease"
      ],
      "interventions": [
        {
          "name": "Pristine™ Long-Term Hemodialysis Catheter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "C. R. Bard",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 142,
      "start_date": "2022-05-16",
      "completion_date": "2022-09-21",
      "has_results": true,
      "last_update_posted_date": "2024-04-11",
      "last_synced_at": "2026-06-11T01:34:21.780Z",
      "location_count": 6,
      "location_summary": "Dothan, Alabama • New Haven, Connecticut • Shreveport, Louisiana + 3 more",
      "locations": [
        {
          "city": "Dothan",
          "state": "Alabama"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Shreveport",
          "state": "Louisiana"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Raleigh",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05228132"
    },
    {
      "nct_id": "NCT02351258",
      "title": "Community Central Line Infection Prevention Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infection"
      ],
      "interventions": [
        {
          "name": "70% Isopropyl alcohol embedded caps",
          "type": "DEVICE"
        },
        {
          "name": "Usual Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Day",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "1 Day to 35 Years"
      },
      "enrollment_count": 16,
      "start_date": "2015-11",
      "completion_date": "2019-09-09",
      "has_results": true,
      "last_update_posted_date": "2020-05-20",
      "last_synced_at": "2026-06-11T01:34:21.780Z",
      "location_count": 16,
      "location_summary": "Birmingham, Alabama • Little Rock, Arkansas • Aurora, Colorado + 12 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Wilmington",
          "state": "Delaware"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02351258"
    },
    {
      "nct_id": "NCT03672006",
      "title": "t-PA Prophylaxis to Prevent Catheter-associated Thrombosis and Infection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Central Venous Catheter Thrombosis",
        "Central Venous Catheter Associated Bloodstream Infection"
      ],
      "interventions": [
        {
          "name": "alteplase (recombinant t-PA)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Heparin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "Medical College of Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": 20,
      "start_date": "2019-04-22",
      "completion_date": "2019-12-15",
      "has_results": true,
      "last_update_posted_date": "2021-07-13",
      "last_synced_at": "2026-06-11T01:34:21.780Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03672006"
    },
    {
      "nct_id": "NCT02969343",
      "title": "Patient Safety Learning Laboratory: Making Acute Care More Patient-Centered",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Central Line-Associated Bloodstream Infection (CLABSI)",
        "Venous Thromboembolism",
        "Patient Fall",
        "Catheter-Associated Infection",
        "Severe Hypoglycemia",
        "Opioid-Related Severe Adverse Drug Event",
        "Hospital Acquired Pressure Ulcer",
        "Adverse Drug Event",
        "Severe Hospital Acquired Delerium",
        "Rapid Response Related to Arrhythmia"
      ],
      "interventions": [
        {
          "name": "Patient Safety health information technology",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 21000,
      "start_date": "2015-04",
      "completion_date": "2018-12",
      "has_results": false,
      "last_update_posted_date": "2019-07-10",
      "last_synced_at": "2026-06-11T01:34:21.780Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02969343"
    },
    {
      "nct_id": "NCT03898115",
      "title": "Implementation Program to Improve CHG Bathing Compliance",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Central Line-associated Bloodstream Infection (CLABSI)"
      ],
      "interventions": [
        {
          "name": "CHG Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 14,
      "start_date": "2019-05-01",
      "completion_date": "2020-09-30",
      "has_results": false,
      "last_update_posted_date": "2022-07-20",
      "last_synced_at": "2026-06-11T01:34:21.780Z",
      "location_count": 2,
      "location_summary": "Durham, North Carolina • Raleigh, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Raleigh",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03898115"
    }
  ]
}