{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Central+Line+Sepsis",
    "query": {
      "condition": "Central Line Sepsis"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 39,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Central+Line+Sepsis&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:44:16.094Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04756427",
      "title": "Sodium Citrate 4% Locking Solution for Children Requiring Home Parenteral Nutrition",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "CLABSI - Central Line Associated Bloodstream Infection"
      ],
      "interventions": [
        {
          "name": "Sodium Citrate 4% Inj Syringe 3Ml",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": 1,
      "start_date": "2022-03-28",
      "completion_date": "2023-11-28",
      "has_results": true,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-05-22T09:44:16.094Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04756427"
    },
    {
      "nct_id": "NCT00680459",
      "title": "Ethanol Locks for the Treatment of Central Venous Line Infections",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Bloodstream Infection"
      ],
      "interventions": [
        {
          "name": "70% ethanol",
          "type": "DRUG"
        },
        {
          "name": "heparin flush solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Baystate Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "23 Years",
        "sex": "ALL",
        "summary": "6 Months to 23 Years"
      },
      "enrollment_count": 13,
      "start_date": "2008-05",
      "completion_date": "2011-06",
      "has_results": true,
      "last_update_posted_date": "2014-03-12",
      "last_synced_at": "2026-05-22T09:44:16.094Z",
      "location_count": 1,
      "location_summary": "Springfield, Massachusetts",
      "locations": [
        {
          "city": "Springfield",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00680459"
    },
    {
      "nct_id": "NCT05228132",
      "title": "The Pristine Post-Market Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Kidney Failure, Chronic",
        "Hemodialysis Complication",
        "Hemodialysis Catheter Infection",
        "Hemodialysis Access Failure",
        "Central Venous Catheter Related Bloodstream Infection",
        "End Stage Renal Disease"
      ],
      "interventions": [
        {
          "name": "Pristine™ Long-Term Hemodialysis Catheter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "C. R. Bard",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 142,
      "start_date": "2022-05-16",
      "completion_date": "2022-09-21",
      "has_results": true,
      "last_update_posted_date": "2024-04-11",
      "last_synced_at": "2026-05-22T09:44:16.094Z",
      "location_count": 6,
      "location_summary": "Dothan, Alabama • New Haven, Connecticut • Shreveport, Louisiana + 3 more",
      "locations": [
        {
          "city": "Dothan",
          "state": "Alabama"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Shreveport",
          "state": "Louisiana"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Raleigh",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05228132"
    },
    {
      "nct_id": "NCT00027248",
      "title": "Safety and Efficacy of MBI 226 for the Prevention of Central Venous Catheter-Related Bloodstream Infections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Sepsis",
        "Bacteremia",
        "Fungemia"
      ],
      "interventions": [
        {
          "name": "MBI 226",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "BioWest Therapeutics Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 1400,
      "start_date": "2000-09",
      "completion_date": "2003-07",
      "has_results": false,
      "last_update_posted_date": "2005-09-14",
      "last_synced_at": "2026-05-22T09:44:16.094Z",
      "location_count": 1,
      "location_summary": "Lake Bluff, Illinois",
      "locations": [
        {
          "city": "Lake Bluff",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00027248"
    },
    {
      "nct_id": "NCT06884176",
      "title": "CVCs Versus Midline Catheters",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Central Venous Catheter",
        "Midline Catheter",
        "Complication of Catheter"
      ],
      "interventions": [
        {
          "name": "Ultrasound Guided Central Venous Catheter",
          "type": "DEVICE"
        },
        {
          "name": "Ultrasound Guided Midline Catheter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Albert Einstein College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2026-06",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-04-02",
      "last_synced_at": "2026-05-22T09:44:16.094Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06884176"
    },
    {
      "nct_id": "NCT00516360",
      "title": "Study of Chlorhexidine as the Hub Antiseptic to Prevent Catheter Related Infections in Newborn Infants",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Catheterization"
      ],
      "interventions": [
        {
          "name": "3.15% chlorhexidine as daily antiseptic on needleless access port",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "6 Months",
        "sex": "ALL",
        "summary": "Up to 6 Months"
      },
      "enrollment_count": 150,
      "start_date": "2007-07",
      "completion_date": "2008-08",
      "has_results": false,
      "last_update_posted_date": "2008-05-30",
      "last_synced_at": "2026-05-22T09:44:16.094Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00516360"
    },
    {
      "nct_id": "NCT04559334",
      "title": "Compassionate-Use of 4% T-EDTA Lock Solution for Central Venous Lines of Pediatric PN Patients",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Central Line Complication",
        "Central Line-associated Bloodstream Infection (CLABSI)"
      ],
      "interventions": [
        {
          "name": "Tetrasodium EDTA Catheter Lock Solution",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "3 Months to 18 Years"
      },
      "enrollment_count": 15,
      "start_date": "2020-12-21",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-15",
      "last_synced_at": "2026-05-22T09:44:16.094Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04559334"
    },
    {
      "nct_id": "NCT00975923",
      "title": "Safe Critical Care: Testing Improvement Strategies",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Central Line-associated Bloodstream Infection (CLABSI)",
        "Ventilator Associated Pneumonia"
      ],
      "interventions": [
        {
          "name": "Collaborative Group",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Tool Kit",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "1 Year and older"
      },
      "enrollment_count": 59,
      "start_date": "2006-02",
      "completion_date": "2008-04",
      "has_results": true,
      "last_update_posted_date": "2016-01-12",
      "last_synced_at": "2026-05-22T09:44:16.094Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00975923"
    },
    {
      "nct_id": "NCT01365312",
      "title": "Safety and Efficacy Study of Ethanol Locking to Prevent Central Line Infection in Premature Neonates",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Infection Associated With Catheter",
        "Bacteremia",
        "Sepsis"
      ],
      "interventions": [
        {
          "name": "Ethanol lock",
          "type": "DRUG"
        },
        {
          "name": "Heparinized saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "East Carolina University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "32 Weeks",
        "sex": "ALL",
        "summary": "Up to 32 Weeks"
      },
      "enrollment_count": 10,
      "start_date": "2010-02",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2014-10-03",
      "last_synced_at": "2026-05-22T09:44:16.094Z",
      "location_count": 1,
      "location_summary": "Greenville, North Carolina",
      "locations": [
        {
          "city": "Greenville",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01365312"
    },
    {
      "nct_id": "NCT02402257",
      "title": "Central Venous Catheter Insertion Train the Trainer",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "CVC Train the Trainer",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 226,
      "start_date": "2014-01",
      "completion_date": "2018-12",
      "has_results": false,
      "last_update_posted_date": "2019-09-06",
      "last_synced_at": "2026-05-22T09:44:16.094Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02402257"
    }
  ]
}